Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Kristi M Porter"'
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Akademický článek
Chronic hypoxia promotes pulmonary artery endothelial cell proliferation through H2O2-induced 5-lipoxygenase.
Autor: Kristi M Porter, Bum-Yong Kang, Sherry E Adesina, Tamara C Murphy, C Michael Hart, Roy L Sutliff
Publikováno v: PLoS ONE, Vol 9, Iss 6, p e98532 (2014)
Pulmonary Hypertension (PH) is a progressive disorder characterized by endothelial dysfunction and proliferation. Hypoxia induces PH by increasing vascular remodeling. A potential mediator in hypoxia-induced PH development is arachidonate 5-Lipoxygen
Externí odkaz: https://doaj.org/article/f4f73e9c4b3e4203b5716e1eca2d66cf
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2
HIV X4 Variants Increase Arachidonate 5-Lipoxygenase in the Pulmonary Microenvironment and are associated with Pulmonary Arterial Hypertension
Autor: Deborah Molehin, Bum-Yong Kang, Justin M. Smith, Sonia C. Flores, Laurence Huang, Roy L. Sutliff, Cari F. Kessing, Kevin Pruitt, Edgar G. Martinez, Edu B Suárez-Martínez, Bryan McNair, Kaiser M. Bijli, Sushma K. Cribbs, Laura Pumarejo-Gomez, Priscilla Y. Hsue, Brandy E. Wade, Sharilyn Almodovar, David M. Guidot, Kristi M. Porter, William R. Tyor, Ethan A. Salazar, Robert Alexis Lopez-Astacio, Jaritza Perez Hernandez
Publikováno v: Scientific Reports
Scientific reports, vol 10, iss 1
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Pulmonary Arterial Hypertension (PAH) is overrepresented in People Living with Human Immunodeficiency Virus (PLWH). HIV protein gp120 plays a key role in the pathogenesis of HIV-PAH. Genetic changes in HIV gp120 determine viral interactions with chem
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0448f27e10d19cf7422129d34401b7e8
http://europepmc.org/articles/PMC7366722
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3
Human Immunodeficiency Virus‐1 Transgene Expression Increases Pulmonary Vascular Resistance and Exacerbates Hypoxia‐Induced Pulmonary Hypertension Development
Autor: David M. Guidot, Erik R. Walp, Robert L. Raynor, Kristi M. Porter, Shawn Elms, Patrick O. Mitchell, Roy L. Sutliff
Publikováno v: Pulmonary Circulation
Pulmonary arterial hypertension (PAH) is a progressive disease characterized by increased pulmonary arterial resistance and vessel remodeling. Patients living with human immunodeficiency virus-1 (HIV-1) have an increased susceptibility to develop sev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa04c4645c55a0562f72f86b7202beb2
https://doi.org/10.4103/2045-8932.109915
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4
Cathepsin Protease Inhibition Reduces Endometriosis Lesion Establishment
Autor: Manu O. Platt, Neil Sidell, Friedrich Wieser, Catera L. Wilder, Kristi M. Porter
Publikováno v: Reproductive sciences (Thousand Oaks, Calif.). 23(5)
Endometriosis is a gynecologic disease characterized by the ectopic presence of endometrial tissue on organs within the peritoneal cavity, causing debilitating abdominal pain and infertility. Current treatments alleviate moderate pain symptoms associ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7157f9fee85dbc519209b61a234674d1
https://pubmed.ncbi.nlm.nih.gov/26482207
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5
HIV-1, Reactive Oxygen Species and Vascular Complications
Autor: Roy L. Sutliff, Kristi M. Porter
Over 1 million people in the United States and 33 million individuals worldwide suffer from HIV/AIDS. Since its discovery, HIV/AIDS has been associated with an increased susceptibility to opportunistic infection due to immune dysfunction. Highly acti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d4f81127f154501d1127e04db997a5
https://europepmc.org/articles/PMC3377788/
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10
HIV-1-induced pulmonary oxidative and nitrosative stress: exacerbated response to endotoxin administration in HIV-1 transgenic mouse model
Autor: Po-Yung Cheng, Dean P. Jones, Barbara A. Jacob, Shawn Elms, Kristi M. Porter, Roy L. Sutliff
Publikováno v: American journal of physiology. Lung cellular and molecular physiology. 291(4)
Human immunodeficiency virus (HIV)-1 causes lung disease by increasing the host's susceptibility to pathogens. HIV-1 also causes an increase in systemic oxidative/nitrosative stress, perhaps enhancing the deleterious effects of secondary infections.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa0c8e84f682a61575d81ea58a01f5e3
https://pubmed.ncbi.nlm.nih.gov/16728526
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