Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Kristi L. Neufeld"'
Autor:
Kristi L. Neufeld
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 3, Pp 799-800 (2023)
Externí odkaz:
https://doaj.org/article/814f92dab5e54779bf7096092217f982
Autor:
Lan Lan, Hao Liu, Amber R. Smith, Carl Appelman, Jia Yu, Sarah Larsen, Rebecca T. Marquez, Xiaoqing Wu, Frank Y. Liu, Philip Gao, Ragul Gowthaman, John Karanicolas, Roberto N. De Guzman, Steven Rogers, Jeffrey Aubé, Kristi L. Neufeld, Liang Xu
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-14 (2018)
Abstract Background The Musashi (MSI) family of RNA-binding proteins is best known for the role in post-transcriptional regulation of target mRNAs. Elevated MSI1 levels in a variety of human cancer are associated with up-regulation of Notch/Wnt signa
Externí odkaz:
https://doaj.org/article/467b8685db114a03a77638f0b45279ce
Autor:
Lan Lan, Carl Appelman, Amber R. Smith, Jia Yu, Sarah Larsen, Rebecca T. Marquez, Hao Liu, Xiaoqing Wu, Philip Gao, Anuradha Roy, Asokan Anbanandam, Ragul Gowthaman, John Karanicolas, Roberto N. De Guzman, Steven Rogers, Jeffrey Aubé, Min Ji, Robert S. Cohen, Kristi L. Neufeld, Liang Xu
Publikováno v:
Molecular Oncology, Vol 9, Iss 7, Pp 1406-1420 (2015)
Musashi‐1 (MSI1) is an RNA‐binding protein that acts as a translation activator or repressor of target mRNAs. The best‐characterized MSI1 target is Numb mRNA, whose encoded protein negatively regulates Notch signaling. Additional MSI1 targets i
Externí odkaz:
https://doaj.org/article/d4dfefcc31d849b3b8af1661a9c48642
Autor:
Kristi L. Neufeld, Thelma T. Chiremba
Publikováno v:
Molecular Biology of the Cell
Evolutionarily conserved RNA-binding protein Musashi1 (Msi1) can regulate developmentally relevant genes. Here we report the generation and characterization of a mouse model that allows inducible Msi1 overexpression in a temporal and tissue-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1ed01a6abb4c484e96697ba00b0f5d
https://doi.org/10.1091/mbc.e20-03-0206
https://doi.org/10.1091/mbc.e20-03-0206
Autor:
Minli Xing, Kristi L. Neufeld, Audrey L. Lamb, Justin T. Douglas, Aaron J. Rudeen, W. Hayes McDonald
Publikováno v:
Biochemistry
The tumor suppressor Adenomatous polyposis coli (APC) is a large, multidomain protein with many identified cellular functions. The best characterized role of APC is to scaffold a protein complex that negatively regulates Wnt signaling via β-catenin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94adb8b72ae5df4769bf60c437bac768
https://pubmed.ncbi.nlm.nih.gov/32941008
https://pubmed.ncbi.nlm.nih.gov/32941008
Autor:
Anuradha Roy, Lan Lan, Liang Xu, Minli Xing, Xiaoqing Wu, Kristi L. Neufeld, John Karanicolas, Carl Appelman, Ke Li, Roberto N. De Guzman, Ragul Gowthaman, Jinan Wang, Amber D. Somoza, Clay C. C. Wang, Jiajun Liu, Amber R. Smith, Berl R. Oakley, Yinglong Miao
Publikováno v:
Cancers
Volume 12
Issue 8
Cancers, Vol 12, Iss 2221, p 2221 (2020)
Volume 12
Issue 8
Cancers, Vol 12, Iss 2221, p 2221 (2020)
RNA-binding protein Musashi-1 (MSI1) is a key regulator of several stem cell populations. MSI1 is involved in tumor proliferation and maintenance, and it regulates target mRNAs at the translational level. The known mRNA targets of MSI1 include Numb,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e7e0795e4148eaee3bef3e022c99c8
Autor:
Christian L. Gomez, Kristi L. Neufeld
Publikováno v:
Experimental physiologyREFERENCES. 105(12)
New findings What is the central question of this study? What is the localization and distribution pattern of adenomatous polyposis coli (APC) in intestinal epithelial cells? Does this distribution change in different regions of the colon or in the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a917c2e63cf0d6d18798938cdf87722e
https://pubmed.ncbi.nlm.nih.gov/33150708
https://pubmed.ncbi.nlm.nih.gov/33150708
Publikováno v:
Cancers, Vol 12, Iss 2114, p 2114 (2020)
Cancers
Volume 12
Issue 8
Cancers
Volume 12
Issue 8
The Wnt/&beta
catenin signaling pathway is deregulated in nearly all colorectal cancers (CRCs), predominantly through mutation of the tumor suppressor Adenomatous Polyposis Coli (APC). APC mutation is thought to allow a &ldquo
just-right&rd
catenin signaling pathway is deregulated in nearly all colorectal cancers (CRCs), predominantly through mutation of the tumor suppressor Adenomatous Polyposis Coli (APC). APC mutation is thought to allow a &ldquo
just-right&rd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::401994d4b8288d2b56d6a8e44d0bd2f1
https://www.mdpi.com/2072-6694/12/8/2114
https://www.mdpi.com/2072-6694/12/8/2114
Autor:
Lan, Lan, Jiajun, Liu, Minli, Xing, Amber R, Smith, Jinan, Wang, Xiaoqing, Wu, Carl, Appelman, Ke, Li, Anuradha, Roy, Ragul, Gowthaman, John, Karanicolas, Amber D, Somoza, Clay C C, Wang, Yinglong, Miao, Roberto, De Guzman, Berl R, Oakley, Kristi L, Neufeld, Liang, Xu
Publikováno v:
Cancers
RNA-binding protein Musashi-1 (MSI1) is a key regulator of several stem cell populations. MSI1 is involved in tumor proliferation and maintenance, and it regulates target mRNAs at the translational level. The known mRNA targets of MSI1 include Numb,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0eb8ef974a06014a7fe6c6989c67a83a
https://pubmed.ncbi.nlm.nih.gov/32784494
https://pubmed.ncbi.nlm.nih.gov/32784494
Autor:
Ning Li, Jonathan X. Chia, Tatyana Svitkina, Kristi L. Neufeld, Nadia Efimova, Christopher J. Lengner, Changsong Yang
Publikováno v:
The Journal of Cell Biology
Efimova et al. show that adenomatous polyposis coli (APC) at microtubule tips triggers assembly of a branched actin network when the microtubule hits the plasma membrane in neuronal growth cones. These findings uncover a new mechanism of microtubule-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b36a670c64abda56fa972b6e32a579d3
https://pubmed.ncbi.nlm.nih.gov/32597939
https://pubmed.ncbi.nlm.nih.gov/32597939