Výsledky vyhledávání - "Kristi Bemis"

Establishment of an ex vivo model of monocytes-derived macrophages differentiated from peripheral blood mononuclear cells (PBMCs) from HIV-1 transgenic rats

Autor: Frank Denaro, Agostino Riva, Kristi Bemis, Davide Zella, Sabrina Curreli, Marialaura Amadio, Renata Mazzucchelli, William Reid, Joseph Bryant, Massimo Galli

Publikováno v: Molecular Immunology. 41:979-984

It has been developed an HIV type 1 transgenic rat model (HIV-1 Tg Rat) which contains a gag-pol-deleted HIV-1 provirus regulated by the viral LTR promoter. Although it harbors a non infectious provirus, efficient viral expression occurs in different

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cceff15f51d056902c68406bd9b5803c
https://doi.org/10.1016/j.molimm.2004.06.023

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Human Primary CD4+T Cells Activated in the Presence of IFN-α2b Express Functional Indoleamine 2,3-Dioxygenase

Autor: Fabio Romerio, Sabrina Curreli, Prisco Mirandola, Paola Barion, Davide Zella, Kristi Bemis

Publikováno v: Journal of Interferon & Cytokine Research. 21:431-437

Indoleamine 2,3-dioxygenase (IDO) is the rate-limiting enzyme in the catabolism of tryptophan. By creating a local microenvironment in which levels of tryptophan are low, IDO-expressing antigen-presenting cells (APC) could regulate T cell activation.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938d5073528d52cf4efc19705d46aa32
https://doi.org/10.1089/107999001750277916

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Enforced expression of humanbcl‐2in CD4+T cells enhances human herpesvirus 7 replication and induction of cytopathic effects

Autor: Paola Secchiero, Lucia Bertolaso, Kristi Bemis, Robert C. Gallo, Giorgio Zauli, Davide Gibellini, Silvano Capitani, Daniele Ricci

Publikováno v: European Journal of Immunology. 28:1587-1596

The cytopathic effects (CPE) resulting from the infection of CD4+ T cells by human herpes-virus 7 (HHV-7) comprises two major mechanisms: generation of large polyploid cells, which eventually undergo necrotic lysis, and apoptosis, predominantly occur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3a988e68b8e16569ab511596836743ce
https://doi.org/10.1002/(sici)1521-4141(199805)28:05<1587::aid-immu1587>3.0.co

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The mRNA Binding Proteins HuR and Tristetraprolin Regulate Cyclooxygenase 2 Expression During Colon Carcinogenesis

Autor: Robert L. Price, Edsel A. Peña, Kristi Bemis–Standoli, Sandhya Sanduja, Lisa E. Young, Dan A. Dixon

Background & Aims During tumorigenesis, loss of rapid messenger RNA (mRNA) decay allows for overexpression of cancer-associated genes. The RNA-binding proteins Hu antigen R (HuR) and tristetraprolin (TTP) bind AU-rich elements in the 3′ untranslate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d134d3c3744594b89f826842fa43c1
https://europepmc.org/articles/PMC3742387/

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Expression of COX-2 in platelet-monocyte interactions occurs via combinatorial regulation involving adhesion and cytokine signaling

Autor: Stephen M. Prescott, Dan A. Dixon, Neal D. Tolley, Jason D. Morrow, Guy A. Zimmerman, Andrew S. Weyrich, Mark L. Martinez, Kristi Bemis-Standoli

Publikováno v: The Journal of clinical investigation. 116(10)

Tight regulation of COX-2 expression is a key feature controlling eicosanoid production in atherosclerosis and other inflammatory syndromes. Adhesive interactions between platelets and monocytes occur in these conditions and deliver specific signals

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337f990bb3e4c1960357cd5e2716812c
https://pubmed.ncbi.nlm.nih.gov/16998585

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Ionizing radiation sensitizes erythroleukemic cells but not normal erythroblasts to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated cytotoxicity by selective up-regulation of TRAIL-R1

Autor: Giorgio Zauli, Davide Gibellini, Kristi Bemis, Sebastiano Miscia, Loris Zamai, Giuseppe Visani, Paola Secchiero, Roberta Di Pietro, R. Rana

Cytotoxic activity of tumor necrosis factor–related apoptosis-inducing ligand (TRAIL/Apo-2 ligand), used alone or in different combinations with either a low (1.5 Gy) or a high (15 Gy) single dose of ionizing radiation (IR), was investigated on ery

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490e1720339fee73861e7f867860e6a7
http://hdl.handle.net/11392/1208711

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Human herpesvirus 7 infection induces profound cell cycle perturbations coupled to disregulation of cdc2 and cyclin B and polyploidization of CD4(+) T cells

Autor: Lucia Bertolaso, Davide Gibellini, Giorgio Zauli, Kristi Bemis, Marco Vitale, Arrigo Aleotti, Paola Secchiero, Genoveffa Franchini, Robert C. Gallo, Luca Casareto, Silvano Capitani

Publikováno v: Scopus-Elsevier
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Human herpesvirus 7 (HHV-7) infection of both primary CD4+ T lymphocytes and SupT1 lymphoblastoid T-cell line induced a progressive accumulation of cells exibiting a gap 2/mitosis (G2/M) and polyploid content coupled to an increased cell size. The ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ee1a963d8d1dd811920a0bf216a0a2
https://pubmed.ncbi.nlm.nih.gov/9716597

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