Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Krister Karlsson"'
Publikováno v:
Harmful Algae. 4:163-166
Cyanobacterial bloom samples from the Gulf of Finland (northern Baltic Sea) were collected in July 2003 and analyzed for microcystins and nodularins, cyanobacterial peptide hepatotoxins, by ELISA, HPLC-UV and LC-MS. The blooms consisted mainly of the
Publikováno v:
Environmental Toxicology. 20:381-389
The matrix effects and signal response in LC-MS analysis of six microcystins and nodularin-R were studied in mussels and liver samples from the common eider and rainbow trout. The instrumentation used in the study was a triple quadrupole MS with elec
Publikováno v:
Environmental Science & Technology. 38:6025-6031
Cyanobacteria are known producers of cytotoxins, hepatotoxins, and neurotoxins. The main toxins are microcystins, cyclic heptapeptide hepatotoxins, produced by strains of several cyanobacterial genera frequently found in eutrophied freshwaters. Due t
Publikováno v:
Environmental Toxicology. 18:284-288
Livers of flounders caught during August 1995 from the western Gulf of Finland and the Archipelago Sea were analyzed for nodularin-R (NODLN) by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and liquid chromatography-ele
Autor:
Anne Kiuru, Zhurong Liu, Madeleine Le Grevès, Qin Zhou, Krister Karlsson, Pia Johansson, Fred Nyberg
Publikováno v:
Karolinska Institutet
In this study the level of a substance P endopeptidase (SPE)-like activity was measured in different regions of the rat central nervous system (CNS) after chronic administration of morphine. Male rats (200–220 g) were randomly divided into four gro
Publikováno v:
Neuroscience Research. 27:185-189
The levels of β-endorphin and Met-enkephalin-Arg-Phe (MEAP) immunoreactivity in various brain regions (including amygdala, cortex, hippocampus, hypothalmus, nucleus accumbens, pituitary and ventral tegmental area) were studied in male rats subjected
Publikováno v:
Preparative Biochemistry and Biotechnology. 27:59-78
Two enzymes with substance P degrading activity were purified from the membrane bound fraction of the rat spinal cord. The purified enzymes were characterized with regard to biochemical and kinetic properties. One of the enzymes exhibited close simil
Autor:
Krister Karlsson, Sergei M. Gryaznov, Katarina Nordfjäll, Ylva Paulsson-Karlsson, Xuping Wu, Shirin Smavadati, Michael Bergqvist, Simon Ekman, Fredrik Qvarnström, Martin Simonsson
Publikováno v:
Biochimica et biophysica acta. 1823(12)
Telomerase is mainly active in human tumor cells, which provides an opportunity for a therapeutic window on telomerase targeting. We sought to evaluate the potential of the thio-phosphoramidate oligonucleotide inhibitor of telomerase, imetelstat, as
Autor:
Vesa O. Sipiä, Harri Kankaanpää, Laura Sneitz, Maija Huttunen, Kirsi Hyvärinen, Krister Karlsson, Jussi Meriluoto, Olli Sjövall, Janne Härkönen, Miikka Olin
Publikováno v:
Environmental pollution (Barking, Essex : 1987). 157(4)
This seven-year survey was primarily targeted to quantification of production of nodularin-R (NOD-R), a cyclic pentapeptide hepatotoxin, in Baltic Sea cyanobacteria waterblooms. Additionally, NOD-R and microcystin-LR (MC-LR; a cyclic heptapeptide tox
Autor:
Jussi Meriluoto, Orla Allis, Vesa O. Sipiä, Ambrose Furey, Pekka J. Vuorinen, Marja Keinänen, Kevin J. James, Eija Rimaila-Pärnänen, Krister Karlsson, Ulla Perttilä
Publikováno v:
Archives of environmental contamination and toxicology. 57(1)
Nodularin (NODLN) is a cyclic pentapeptide hepatotoxin produced by the cyanobacterium Nodularia spumigena, which occurs regularly in the Baltic Sea during the summer season. In this study flounder (Platichthys flesus L.) was orally exposed to NODLN e