Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Krister Henriksson"'
Autor:
Anna Ollerstam, Krister Henriksson, Patrick Stephen Johnson, Martin A. Carnerup, Martin Stahlhut, Dack Kevin Neil, Stefan Eirefelt
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 30:127402
Steroidal glucocorticoids (GR agonists) have been widely used for the topical treatment of skin disorders, including atopic dermatitis. They are a very effective therapy, but they are associated with both unwanted local effects in the skin (skin thin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e52eddab6e415d6398be335db12327fd
https://doi.org/10.1016/j.bmcl.2020.127402
https://doi.org/10.1016/j.bmcl.2020.127402
Autor:
Markus Berger, Ramon Hendrickx, Martin Lindsjö, Stinabritt Nilsson, Tina Jellesmark Jensen, Tomas Klingstedt, Wayne Russell, Hartmut Rehwinkel, Martin Hemmerling, Thomas Hansson, Nafizal Hossain, Stefan Eirefelt, Balint Gabos, Henrik Johansson, Grigorios Nikitidis, Svetlana Ivanova, John Steele, Matti Lepistö, Eskil Johnsson, Anne-Helene Jansson, Anna Abrahamsson, Carina Kärrman Mårdh, Krister Henriksson, Jan Dahmén, Karl Edman, Anders Eriksson, Ulrika Tehler, Anders Jerre, Irene Mile, Lisa Wissler
Publikováno v:
Journal of medicinal chemistry. 60(20)
A class of potent, nonsteroidal, selective indazole ether-based glucocorticoid receptor modulators (SGRMs) was developed for the inhaled treatment of respiratory diseases. Starting from an orally available compound with demonstrated anti-inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f24c66ce17b946cd661fe6628c9bfcc
https://pubmed.ncbi.nlm.nih.gov/28937774
https://pubmed.ncbi.nlm.nih.gov/28937774
Autor:
Anders Jerre, Håkan Bladh, Stefan Bäckström, Karl Edman, Matti Lepistö, Amir Smailagic, Ann Tjörnebo, Jan Dahmén, John D. Taylor, Liz Kinchin, Stinabritt Nilsson, Krister Henriksson, Per Hillertz, Vijakumar Hulikal, Charlotte Kåse, Ragnhild Ahlgren, Malena Bengtsson, Irene Mile, Thomas Hansson, Lisa Wissler
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:2571-2577
We report the discovery of highly potent and selective non-steroidal glucocorticoid receptor modulators with PK properties suitable for inhalation. A high throughput screen of the AstraZeneca compound collection identified sulfonamide 3 as a potent n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32428237e19d1fdb048c6e811be7a095
https://doi.org/10.1016/j.bmcl.2014.03.070
https://doi.org/10.1016/j.bmcl.2014.03.070
Autor:
B. R. Srinivasa, Johan Broddefalk, Kristina Stenvall, Jan Dahmén, Hans Roland Lonn, Krister Henriksson, Jan Kihlberg, Marita Bengtsson
Publikováno v:
Glycoconjugate Journal. 15:223-231
The 2-bromoethyl β-glycosides of the disaccharide galabiose [Gal(α1-4)Gal] and the trisaccharides globotriose [Gal(α1-4)Gal(β1-4)Glc] and 3′-sialyllactose [Neu5Ac(α2-3)Gal(β1-4)Glc] have been prepared by improved routes. The 2-bromoethyl glyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ad6759acce3251ad1ee6990c5968d4b
https://doi.org/10.1023/a:1006988810800
https://doi.org/10.1023/a:1006988810800