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Human sperm cells can form paracetamol metabolite AM404 that directly interferes with sperm calcium signalling and function through a CatSper-dependent mechanism.

Autor: Rehfeld, A, Frederiksen, H, Rasmussen, R H, David, A, Chaker, J, Nielsen, B S, Nielsen, J E, Juul, A, Skakkebæk, N E, Kristensen, D M

Publikováno v: Human Reproduction; May2022, Vol. 37 Issue 5, p922-935, 14p

Ibuprofen is deleterious for the development of first trimester human fetal ovary ex vivo

Autor: Leverrier-Penna, S., Mitchell, R. T., Becker, E., Lecante, L., Ben Maamar, M., Homer, N., Lavoue, V., Kristensen, D. M., Dejucq-Rainsford, N., Jegou, B., Mazaud-Guittot, S.

Publikováno v: Human Reproduction
Human Reproduction, Oxford University Press (OUP), 2018, 33 (3), pp.482-493. ⟨10.1093/humrep/dex383⟩
Human Reproduction, 2018, 33 (3), pp.482-493. ⟨10.1093/humrep/dex383⟩
Leverrier-Penna, S, Mitchell, R, Becker, E B E, Lecante, L, Ben Maamar, M, Homer, N, Lavoué, V, Kristensen, D M, Dejucq-Rainsford, N, Jégou, B & Mazaud-guittot, S 2018, ' Ibuprofen is deleterious for the development of first trimester human fetal ovary ex vivo ', Human Reproduction . https://doi.org/10.1093/humrep/dex383
Leverrier-Penna, S, Mitchell, R T, Becker, E, Lecante, L, Ben Maamar, M, Homer, N, Lavoue, V, Kristensen, D M, Dejucq-Rainsford, N, Jegou, B & Mazaud-Guittot, S 2018, ' Ibuprofen is deleterious for the development of first trimester human fetal ovary ex vivo ', Human Reproduction, vol. 33, no. 3, pp. 482-493 . https://doi.org/10.1093/humrep/dex383

International audience; STUDY QUESTION Does ibuprofen use during the first trimester of pregnancy interfere with the development of the human fetal ovary? SUMMARY ANSWER In human fetuses, ibuprofen exposure is deleterious for ovarian germ cells. WHAT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ab73175ee48b06363417980ee3845888
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01739999/file/dex383.pdf

A novel double staining strategy for improved detection of testicular carcinoma in situ cells in human semen samples.

Autor: Nielsen, J. E.¹, Kristensen, D. M.¹, Almstrup, K.¹, Jørgensen, A.¹, Olesen, I. A.¹, Jacobsen, G. K.², Horn, T.³, Skakkebæk, N. E.¹, Leffers, H.¹, Rajpert-De Meyts, E.¹

Publikováno v: Andrologia. Apr2012, Vol. 44 Issue 2, p78-85. 8p. 2 Color Photographs, 1 Diagram, 1 Chart.