Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kristen Zhang"'
Autor:
Kristen Zhang, Jerick Sanchez, Duy Nguyen, Barbra Sasu, Elvin J Lauron, Vidhya Ramanathan, George Nguyen, Cesar Sommer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/5d4b61874df0479a8030ae4c5125f6ec
Autor:
Matthew Walters, Stephen Young, Michael Cecchini, Houston Gilbert, Akshata Udyavar, Daniel DiRenzo, Sean Cho, Lisa Seitz, Kristen Zhang, Amy Anderson, Kimberline Gerrick, Olivia Gardner, Cheng Quah, Juan Jaen, William Grossman
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/4bb49219c48a4df9a64820fd1d9aed2c
Autor:
Matthew J. Walters, Kelsey E. Sivick, Uli Schindler, Jay P. Powers, Stephen W. Young, Jaroslaw Kalisiak, Nikki Kimura, Timothy W. Park, Bhamini Purandare, Susan L. Paprcka, Fangfang Yin, Akshata R. Udyavar, Elaine Ginn, Ada Chen, Kristen Zhang, Daniel DiRenzo, Nell Narasappa, Jesus Banuelos, Annette Becker, Joanne B.L. Tan, Dana Piovesan
Supplementary Data from Targeting CD73 with AB680 (Quemliclustat), a Novel and Potent Small-Molecule CD73 Inhibitor, Restores Immune Functionality and Facilitates Antitumor Immunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb5b5a4e6987b75f7ac46778faa4a20
https://doi.org/10.1158/1535-7163.22522347
https://doi.org/10.1158/1535-7163.22522347
Autor:
Matthew J. Walters, Kelsey E. Sivick, Uli Schindler, Jay P. Powers, Stephen W. Young, Jaroslaw Kalisiak, Nikki Kimura, Timothy W. Park, Bhamini Purandare, Susan L. Paprcka, Fangfang Yin, Akshata R. Udyavar, Elaine Ginn, Ada Chen, Kristen Zhang, Daniel DiRenzo, Nell Narasappa, Jesus Banuelos, Annette Becker, Joanne B.L. Tan, Dana Piovesan
Supplementary Figure from Targeting CD73 with AB680 (Quemliclustat), a Novel and Potent Small-Molecule CD73 Inhibitor, Restores Immune Functionality and Facilitates Antitumor Immunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35adf1efc1bd618059ec8b92f7b406e6
https://doi.org/10.1158/1535-7163.22522341
https://doi.org/10.1158/1535-7163.22522341
Autor:
Matthew J. Walters, Kelsey E. Sivick, Uli Schindler, Jay P. Powers, Stephen W. Young, Jaroslaw Kalisiak, Nikki Kimura, Timothy W. Park, Bhamini Purandare, Susan L. Paprcka, Fangfang Yin, Akshata R. Udyavar, Elaine Ginn, Ada Chen, Kristen Zhang, Daniel DiRenzo, Nell Narasappa, Jesus Banuelos, Annette Becker, Joanne B.L. Tan, Dana Piovesan
T cells play a critical role in the control of cancer. The development of immune checkpoint blockers (ICB) aimed at enhancing antitumor T-cell responses has revolutionized cancer treatment. However, durable clinical benefit is observed in only a subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db083be516cf4170981d0503a34a58b
https://doi.org/10.1158/1535-7163.c.6543339.v1
https://doi.org/10.1158/1535-7163.c.6543339.v1
Autor:
Dana Piovesan, Joanne B.L. Tan, Annette Becker, Jesus Banuelos, Nell Narasappa, Daniel DiRenzo, Kristen Zhang, Ada Chen, Elaine Ginn, Akshata R. Udyavar, Fangfang Yin, Susan L. Paprcka, Bhamini Purandare, Timothy W. Park, Nikki Kimura, Jaroslaw Kalisiak, Stephen W. Young, Jay P. Powers, Uli Schindler, Kelsey E. Sivick, Matthew J. Walters
Publikováno v:
Molecular Cancer Therapeutics. 21:948-959
T cells play a critical role in the control of cancer. The development of immune checkpoint blockers (ICB) aimed at enhancing antitumor T-cell responses has revolutionized cancer treatment. However, durable clinical benefit is observed in only a subs
Autor:
Hsinyuan Cheng, Michael Yi, Michael Bethune, Eric Gschweng, Melinda Au, Duy Nguyen, Kristen Zhang, Tanu Shenoy, Barbra Sasu, Thomas Van Blarcom, Cesar Sommer
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Kristen Zhang, Michael Cecchini, Kimberline Gerrick, Juan C. Jaen, Olivia Gardner, Amy E. Anderson, Lisa Seitz, Akshata Udyavar, Matthew Walters, William Grossman, Daniel DiRenzo, Sean Cho, Stephen P. Young, Houston Gilbert, Cheng Quah
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background The release of ATP from dying cancer cells in response to platinum-based chemotherapy increases extracellular adenosine, which binds to and activates A2aR and A2bR receptors to generate an immunosuppressive microenvironment. This is mediat
Autor:
Daniel DiRenzo, Devika Ashok, Amy E. Anderson, Akshata Udyavar, Joanne B. Tan, Irene M. Luu, Kristen Zhang, Jenna L. Jeffrey, Lisa Seitz, Manmohan R. Leleti, Stephen W. Young, Jay P. Powers, Matthew J. Walters
Publikováno v:
Cancer Research. 79:3168-3168
BACKGROUND: The tumor microenvironment (TME) contains high levels of immunosuppressive adenosine (ADO), which activates the A2aR and A2bR receptors on immune cells, leading to an ineffective anti-tumor response. Ecto-5’-nucleotidase (CD73) and tiss
Autor:
Matthew J. Walters, Tim Park, Kristen Zhang, Devika Ashok, Manmohan Reddy Leleti, Amber Pham, Kenneth V. Lawson, Ada Chen, Joanne B.L. Tan, Elaine Ginn, Xiaoning Zhao, Anderson Amy Elizabeth, Jarek Kalisiak, Jesus Banuelos, Jie Chen, Jay P. Powers, Jenna Jeffreys
Publikováno v:
Cancer Immunology Research. 7:A157-A157
Introduction: Extracellular adenosine (ADO), present at high concentrations in the tumor microenvironment (TME), suppresses immune function via inhibition of T-cell, natural killer (NK) cell, and dendritic cell (DC) activation. Intratumoral generatio