Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kristen T. Thomas"'
Autor:
Mary H. Patton, Kristen T. Thomas, Ildar T. Bayazitov, Kyle D. Newman, Nathaniel B. Kurtz, Camenzind G. Robinson, Cody A. Ramirez, Alexandra J. Trevisan, Jay B. Bikoff, Samuel T. Peters, Shondra M. Pruett-Miller, Yanbo Jiang, Andrew B. Schild, Anjana Nityanandam, Stanislav S. Zakharenko
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114503- (2024)
Summary: Synaptic plasticities, such as long-term potentiation (LTP) and depression (LTD), tune synaptic efficacy and are essential for learning and memory. Current studies of synaptic plasticity in humans are limited by a lack of adequate human mode
Externí odkaz:
https://doaj.org/article/0879bdaf39594d3bb0c97326e7c2bfec
Autor:
Kristen T. Thomas, Anaïs Vermare, Suzannah O. Egleston, Yong-Dong Wang, Ashutosh Mishra, Tong Lin, Junmin Peng, Stanislav S. Zakharenko
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
MicroRNA (miRNA) dysregulation is well-documented in psychiatric disease, but miRNA dynamics remain poorly understood during adolescent and early adult brain maturation, when symptoms often first appear. Here, we use RNA sequencing to examine miRNAs
Externí odkaz:
https://doaj.org/article/839e3032ec8a483ea347018fe1f1cac8
Publikováno v:
Cells, Vol 10, Iss 10, p 2679 (2021)
Mounting evidence implicates microRNAs (miRNAs) in the pathology of schizophrenia. These small noncoding RNAs bind to mRNAs containing complementary sequences and promote their degradation and/or inhibit protein synthesis. A single miRNA may have hun
Externí odkaz:
https://doaj.org/article/e6eb22009bc9491c9472dbc41a4e527c
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Since the discovery of the first microRNA 25 years ago, microRNAs (miRNAs) have emerged as critical regulators of gene expression within the mammalian brain. miRNAs are small non-coding RNAs that direct the RNA induced silencing complex to complement
Externí odkaz:
https://doaj.org/article/57ab2cbe04394d9f962ec1e004ad1937
Autor:
Christina Gross, Xiaodi Yao, Tobias Engel, Durgesh Tiwari, Lei Xing, Shane Rowley, Scott W. Danielson, Kristen T. Thomas, Eva M. Jimenez-Mateos, Lindsay M. Schroeder, Raymund Y.K. Pun, Steve C. Danzer, David C. Henshall, Gary J. Bassell
Publikováno v:
Cell Reports, Vol 17, Iss 1, Pp 37-45 (2016)
Seizures are bursts of excessive synchronized neuronal activity, suggesting that mechanisms controlling brain excitability are compromised. The voltage-gated potassium channel Kv4.2, a major mediator of hyperpolarizing A-type currents in the brain, i
Externí odkaz:
https://doaj.org/article/1115fba5355d4bb8aa6621fd1f487c00
Publikováno v:
Journal of neuroimmunology. 223(1-2)
Background While the effects of a proatherogenic diet have been widely studied in the context of systemic inflammation, much less is known about its effects on central or brain inflammation and its modulation with age. In this study, we examined the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1777639747c68a67aae232523d7b1bd3
https://pubmed.ncbi.nlm.nih.gov/20435353
https://pubmed.ncbi.nlm.nih.gov/20435353
Age-related severity of focal ischemia in female rats is associated with impaired astrocyte function
Publikováno v:
Neurobiology of Aging. 33:1123.e1-1123.e16
In middle-aged female rats, focal ischemia leads to a larger cortical infarction as compared with younger females. To determine if stroke-induced cytotoxicity in middle-aged females was associated with impaired astrocyte function, astrocytes were har
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3d301e69f4b8be7f07c8ac494eb7b9
https://doi.org/10.1016/j.neurobiolaging.2011.11.007
https://doi.org/10.1016/j.neurobiolaging.2011.11.007