Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Kristen Spencer"'
Autor:
Ann W. Silk, Biren Saraiya, Roman Groisberg, Nancy Chan, Kristen Spencer, Eugenia Girda, Weichung Shih, Marisa Palmeri, Tracie Saunders, Robert M. Berman, Vlad Coric, Suzie Chen, Andrew Zloza, Joshua Vieth, Janice M. Mehnert, Jyoti Malhotra
Publikováno v:
European Journal of Medical Research, Vol 27, Iss 1, Pp 1-7 (2022)
Abstract Background Glutamate signaling activates MAPK and PI3K/AKT pathways in tumor cells. Treatment with riluzole, a glutamate release inhibitor, has been previously shown to be safe in melanoma patients and produced biologic effects, but did not
Externí odkaz:
https://doaj.org/article/016991f14f514560b82ba32849371847
Autor:
Rebecca Kristeleit, Juan Martin-Liberal, Kristen Spencer, Janice M Mehnert, Maria Vieito, Elizabeth J Davis, Angela Orcurto, Thomas Condamine, Daniel C Cho, Jennifer Pulini, Rowan E Miller, Sarah P Blagden, Dominik Berthold, Dana B Cardin, Prashanth Hari Dass, John E Janik, Jason Clark, Xuejun Chen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 10 (2022)
Background OX40 is a costimulatory receptor upregulated on antigen-activated T cells and constitutively expressed on regulatory T cells (Tregs). INCAGN01949, a fully human immunoglobulin G1κ anti-OX40 agonist monoclonal antibody, was designed to pro
Externí odkaz:
https://doaj.org/article/ac1ed19fc2ac410aa1aabfc845b35fef
Autor:
Maitri Kalra, Elizabeth Henry, Kelly McCann, Meghan S Karuturi, Jean G Bustamante Alvarez, Amanda Parkes, Robert Wesolowski, Mei Wei, Sarah S Mougalian, Gregory Durm, Angel Qin, Caitlin Schonewolf, Meghna Trivedi, Avan J Armaghani, Frederick H Wilson, Wade T Iams, Anita A Turk, Praveen Vikas, Michael Cecchini, Sam Lubner, Priyadarshini Pathak, Kristen Spencer, Vadim S Koshkin, Matthew K Labriola, Catherine H Marshall, Katy E Beckermann, Marina N Sharifi, Anthony C Bejjani, Varsha Hotchandani, Samir Housri, Nadine Housri
Publikováno v:
JMIR Cancer, Vol 8, Iss 2, p e33859 (2022)
BackgroundExpert knowledge is often shared among multidisciplinary academic teams at tumor boards (TBs) across the country, but these conversations exist in silos and do not reach the wider oncology community. ObjectiveUsing an oncologist-only quest
Externí odkaz:
https://doaj.org/article/b5128dc2db1f4f718a05df5e4722645d
Autor:
Rebecca Kristeleit, Howard Burris, Kristen Spencer, Sarina Piha-Paul, Hans Prenen, Tara Mitchell, David Pinato, Solmaz Sahebjam, Donna Graham, Nuria Kotecki, Eric Van Cutsem, Brant Delafontaine, Thomas Karasic, Jeannie Daniel, Kevin O’Hayer, Ryan Geschwindt
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/7ed5aa6600e64e098a5e3fe1502b2f72
Autor:
Vivek Subbiah, Capucine Baldini, Kristen Spencer, Luis Manso, Armando Santoro, Sandip Patel, Joaquina Baranda, Ira Winer, Akhila Wimalasingham, Linda Duska, Polina Khrizman, Griet Van Lancker, Lana Andrianova, Sumandeep Atwal, Keerti Sharma
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/ac09e478413646eb8f4ebcda129483b0
Autor:
Joshua Cinicola, Swati Mamidanna, Nikhil Yegya-Raman, Kristen Spencer, Matthew P. Deek, Salma K. Jabbour
Publikováno v:
Surgical Oncology Clinics of North America. 32:433-459
Publikováno v:
Drugs. 82:1629-1647
Biliary tract cancers (BTCs) are rare and aggressive tumors that typically present at an advanced stage when surgical resection is no longer considered a therapeutic option. While gemcitabine and cisplatin have been the mainstay of treatment, unique
Autor:
Kristen Spencer, Leontios Pappas, Islam Baiev, Jordan Maurer, Andrea Grace Bocobo, Karen Zhang, Apurva Jain, Anaemy Danner De Armas, Stephanie Reyes, Tri Minh Le, Osama E Rahma, Jennifer Stanton, Thomas T DeLeon, Marc Roth, Mary Linton B Peters, Andrew X Zhu, Jochen K Lennerz, A John Iafrate, Kylie Boyhen, Christine VanCott, Lewis R Roberts, Stacie Lindsey, Nora Horick, Laura Williams Goff, Kabir Mody, Mitesh J Borad, Rachna T Shroff, Robin Kate Kelley, Milind M Javle, Lipika Goyal
Publikováno v:
JNCI: Journal of the National Cancer Institute.
Background Treatment patterns for intrahepatic cholangiocarcinoma (ICC) and extrahepatic cholangiocarcinoma (ECC) differ, but limited studies exist comparing them. This study examines differences in molecular profiling rates and treatment patterns in
Autor:
Kristen Spencer, Howard S. Hochster, Anupama Chundury, H. Richard Alexander, Prateek Gulhati, L.D. Berim, David A. August, Timothy J. Kennedy, Swati Mamidanna, Salma K. Jabbour, Russell C. Langan, Matthew P. Deek, Mutlay Sayan, Patrick McKay Boland, Shane S. Neibart, Miral S. Grandhi
Publikováno v:
J Gastrointest Oncol
BACKGROUND: Neoadjuvant chemoradiotherapy can provide downstaging and improve margin negativity for borderline resectable and resectable pancreatic adenocarcinoma [(B)RPC]. Little is known about the relative efficacy of capecitabine (CAPE)-based vs.
Publikováno v:
Immunotherapy
Aim: Cytokine release syndrome (CRS) is an infrequently described immune-related adverse event of checkpoint inhibitors (CPI). CPI-induced CRS typically presents with fevers, hemodynamic instability and organ dysfunction within 2 weeks of the last tr