Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Kristen S. Purrington"'
Autor:
Kristen S. Purrington, Theresa A. Hastert, K. C. Madhav, Mrudula Nair, Natalie Snider, Julie J. Ruterbusch, Ann G. Schwartz, Elena M. Stoffel, Edward S. Peters, Laura S. Rozek
Publikováno v:
Cancer Medicine, Vol 12, Iss 13, Pp 14623-14635 (2023)
Abstract Background Neighborhood deprivation is associated with both race and cancer incidence, but there is a need to better understand the effect of structural inequities on racial cancer disparities. The goal of this analysis was to evaluate the r
Externí odkaz:
https://doaj.org/article/3d5a3737da8c43d68b2fc91884180570
Publikováno v:
Cancer Medicine, Vol 11, Iss 17, Pp 3304-3311 (2022)
Abstract Background The study was conducted to evaluate racial differences in referral and uptake of genetic counseling (GC) in a clinic‐based population of women with breast cancer. Methods Medical records of 150 breast cancer patients at the Karm
Externí odkaz:
https://doaj.org/article/07aef398f2854706ae59dae40f6c210b
Autor:
Sushma Tatineni, Meri Tarockoff, Nadine Abdallah, Kristen S. Purrington, Hadeel Assad, Rachel Reagle, Nancie Petrucelli, Michael S. Simon
Publikováno v:
Cancer Medicine, Vol 11, Iss 6, Pp 1465-1473 (2022)
Abstract Background There is sparse clinical information on the racial and ethnic distribution of results of multigene panel testing among individuals at high risk for hereditary cancer. Methods We evaluated the results of multigene panel testing acr
Externí odkaz:
https://doaj.org/article/6304b3415d524ce2991599ef57b97df2
Autor:
Emily A. Teslow, Cristina Mitrea, Bin Bao, Ramzi M. Mohammad, Lisa A. Polin, Greg Dyson, Kristen S. Purrington, Aliccia Bollig‐Fischer
Publikováno v:
Molecular Oncology, Vol 13, Iss 4, Pp 894-908 (2019)
Obesity is a risk factor for triple‐negative breast cancer (TNBC) incidence and poor outcomes, but the underlying molecular biology remains unknown. We previously identified in TNBC cell cultures that expression of epigenetic reader methyl‐CpG‐
Externí odkaz:
https://doaj.org/article/a36e2f85375b49759d6f837da7629d52
Autor:
Neb Duric, Mark Sak, Shaoqi Fan, Ruth M. Pfeiffer, Peter J. Littrup, Michael S. Simon, David H. Gorski, Haythem Ali, Kristen S. Purrington, Rachel F. Brem, Mark E. Sherman, Gretchen L. Gierach
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 2, p 367 (2020)
Mammographic percent density (MPD) is an independent risk factor for developing breast cancer, but its inclusion in clinical risk models provides only modest improvements in individualized risk prediction, and MPD is not typically assessed in younger
Externí odkaz:
https://doaj.org/article/91ea4ed5b192485ea5e0d1024a716263
Autor:
Natalie G. Snider, Theresa A. Hastert, Mrudula Nair, Madhav KC, Julie J. Ruterbusch, Ann G. Schwartz, Edward S. Peters, Elena M. Stoffel, Laura S. Rozek, Kristen S. Purrington
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 32:387-397
Background:Racial segregation is linked to poorer neighborhood quality and adverse health conditions among minorities, including worse cancer outcomes. We evaluated relationships between race, neighborhood social disadvantage, and cancer survival.Met
Autor:
Nadine Abdallah, Kristen S. Purrington, Sushma Tatineni, Hadeel Assad, Nancie Petrucelli, Michael S. Simon
Purpose: The prevalence of pathogenic variants in BRCA1 and BRCA2 in populations other than Ashkenazi Jewish (AJ) is not well defined. We describe the racial and ethnic-specific prevalence of BRCA1/2 pathogenic variants and variants of uncertain sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d44864c1c307122cc8b1c7f896f79788
https://doi.org/10.21203/rs.3.rs-1768808/v1
https://doi.org/10.21203/rs.3.rs-1768808/v1
Autor:
Manohar Ratnam, Ann G. Schwartz, Seongho Kim, Kristen S. Purrington, Michael S. Simon, Rayna Rosati, David H. Gorski, Theresa A. Hastert
Publikováno v:
Breast Cancer Res Treat
BACKGROUND: African American women (AAW) die more frequently from estrogen receptor (ER) positive breast cancer than European American women (EAW). We investigated the relationship between race, percent ER staining, treatment, and clinical outcomes.
Autor:
Seongho Kim, Rayna Rosati, Kristen S. Purrington, Manohar Ratnam, David H. Gorski, Michael S. Simon, Ann G. Schwartz
Publikováno v:
Cancer Research. 80:P2-10
Background: African American women (AAW) are more likely to die from hormone receptor positive, HER2-negative breast cancer than European American women (EAW), even when accounting for factors including tumor stage and other clinical characteristics,
Autor:
Sandra M. Swain, Joanne Xiu, Isabel Hart, Paula R. Pohlmann, Michael S. Simon, Kristen S. Purrington, Hadeel Assad, Gregory A. Vidal
Publikováno v:
Cancer Research. 80:P4-09
Background: Among women with invasive breast cancer, the clinical significance of BRCA1 and BRCA2 variants of unknown significance (VUS) remain uncertain. A closer analysis of the somatic mutational profiles of women with invasive breast cancer and B