Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Kristen R. Maynard"'
Autor:
Sean K. Maden, Sang Ho Kwon, Louise A. Huuki-Myers, Leonardo Collado-Torres, Stephanie C. Hicks, Kristen R. Maynard
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-26 (2023)
Abstract Deconvolution of cell mixtures in “bulk” transcriptomic samples from homogenate human tissue is important for understanding disease pathologies. However, several experimental and computational challenges impede transcriptomics-based deco
Externí odkaz:
https://doaj.org/article/934d17d7f4b148708efb8c0435e4ba59
Autor:
Louise A. Huuki-Myers, Kelsey D. Montgomery, Sang Ho Kwon, Stephanie C. Page, Stephanie C. Hicks, Kristen R. Maynard, Leonardo Collado-Torres
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-21 (2023)
Abstract We define and identify a new class of control genes for next-generation sequencing called total RNA expression genes (TREGs), which correlate with total RNA abundance in cell types of different sizes and transcriptional activity. We provide
Externí odkaz:
https://doaj.org/article/461899ba8b9642eaaa65922cbc7e25e9
Autor:
Vijay Sadashivaiah, Madhavi Tippani, Stephanie C. Page, Sang Ho Kwon, Svitlana V. Bach, Rahul A. Bharadwaj, Thomas M. Hyde, Joel E. Kleinman, Andrew E. Jaffe, Kristen R. Maynard
Publikováno v:
BMC Neuroscience, Vol 24, Iss 1, Pp 1-20 (2023)
Abstract Background Multispectral fluorescence imaging coupled with linear unmixing is a form of image data collection and analysis that allows for measuring multiple molecular signals in a single biological sample. Multiple fluorescent dyes, each me
Externí odkaz:
https://doaj.org/article/0dfa134e9c79402a844b850026892a27
Autor:
Brenda Pardo, Abby Spangler, Lukas M. Weber, Stephanie C. Page, Stephanie C. Hicks, Andrew E. Jaffe, Keri Martinowich, Kristen R. Maynard, Leonardo Collado-Torres
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-5 (2022)
Abstract Background Spatially-resolved transcriptomics has now enabled the quantification of high-throughput and transcriptome-wide gene expression in intact tissue while also retaining the spatial coordinates. Incorporating the precise spatial mappi
Externí odkaz:
https://doaj.org/article/fd7c7cc7b496491490ee36657df60094
Autor:
Anthony D. Ramnauth, Kristen R. Maynard, Alisha S. Kardian, BaDoi N. Phan, Madhavi Tippani, Sumita Rajpurohit, John W. Hobbs, Stephanie Cerceo Page, Andrew E. Jaffe, Keri Martinowich
Publikováno v:
Brain Stimulation, Vol 15, Iss 2, Pp 427-433 (2022)
Background: Electroconvulsive therapy (ECT) efficacy is hypothesized to depend on induction of molecular and cellular events that trigger neuronal plasticity. Investigating how electroconvulsive seizures (ECS) impact plasticity in animal models can h
Externí odkaz:
https://doaj.org/article/14f862501964433caa632d20a3251f9d
Autor:
Madhavi Tippani, Heena R. Divecha, Joseph L. Catallini, Sang H. Kwon, Lukas M. Weber, Abby Spangler, Andrew E. Jaffe, Thomas M. Hyde, Joel E. Kleinman, Stephanie C. Hicks, Keri Martinowich, Leonardo Collado-Torres, Stephanie C. Page, Kristen R. Maynard
Publikováno v:
Biological Imaging, Vol 3 (2023)
Spatially resolved transcriptomics (SRT) is a growing field that links gene expression to anatomical context. SRT approaches that use next-generation sequencing (NGS) combine RNA sequencing with histological or fluorescent imaging to generate spatial
Externí odkaz:
https://doaj.org/article/7340b1102c004b1bb09838cdf6156fe8
Autor:
Chaichontat Sriworarat, Annie Nguyen, Nicholas J. Eagles, Leonardo Collado-Torres, Keri Martinowich, Kristen R. Maynard, Stephanie C. Hicks
Publikováno v:
Biological Imaging, Vol 3 (2023)
High-resolution and multiplexed imaging techniques are giving us an increasingly detailed observation of a biological system. However, sharing, exploring, and customizing the visualization of large multidimensional images can be a challenge. Here, we
Externí odkaz:
https://doaj.org/article/eae8bdc7fb7b49d9b405ab84a0327b5c
Autor:
Nicola Micali, Suel-Kee Kim, Marcelo Diaz-Bustamante, Genevieve Stein-O’Brien, Seungmae Seo, Joo-Heon Shin, Brian G. Rash, Shaojie Ma, Yanhong Wang, Nicolas A. Olivares, Jon I. Arellano, Kristen R. Maynard, Elana J. Fertig, Alan J. Cross, Roland W. Bürli, Nicholas J. Brandon, Daniel R. Weinberger, Joshua G. Chenoweth, Daniel J. Hoeppner, Nenad Sestan, Pasko Rakic, Carlo Colantuoni, Ronald D. McKay
Publikováno v:
Cell Reports, Vol 31, Iss 5, Pp - (2020)
Summary: Better understanding of the progression of neural stem cells (NSCs) in the developing cerebral cortex is important for modeling neurogenesis and defining the pathogenesis of neuropsychiatric disorders. Here, we use RNA sequencing, cell imagi
Externí odkaz:
https://doaj.org/article/09028c601a8b4575b9d6ec90dadc6fb0
The basolateral amygdala to lateral septum circuit is critical for regulating social novelty in mice
Autor:
Lionel A. Rodriguez, Sun-Hong Kim, Stephanie C. Page, Claudia V. Nguyen, Elizabeth A. Pattie, Henry L. Hallock, Jessica Valerino, Kristen R. Maynard, Andrew E. Jaffe, Keri Martinowich
Publikováno v:
Neuropsychopharmacology. 48:529-539
Autor:
Erik D. Nelson, Kristen R. Maynard, Kyndall R. Nicholas, Matthew N. Tran, Heena R. Divecha, Leonardo Collado‐Torres, Stephanie C. Hicks, Keri Martinowich
Publikováno v:
Hippocampus.