Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kristen R Trexler"'
Autor:
Rayetta G. Henderson, Timothy W. Lefever, Melissa M. Heintz, Kristen R. Trexler, Susan J. Borghoff, Marcel O. Bonn-Miller
Publikováno v:
Food and Chemical Toxicology. 176:113778
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0afc1aa6239d18e078ba461c4fd185b
https://doi.org/10.1016/j.fct.2023.113778
https://doi.org/10.1016/j.fct.2023.113778
Autor:
Rayetta G. Henderson, Brian T. Welsh, John M. Rogers, Susan J. Borghoff, Kristen R. Trexler, Marcel O. Bonn-Miller, Timothy W. Lefever
Publikováno v:
Food and Chemical Toxicology. 176:113786
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44658cd7694861a170d44b240720043e
https://doi.org/10.1016/j.fct.2023.113786
https://doi.org/10.1016/j.fct.2023.113786
Autor:
Joshua D Gross, Kristen R Trexler, Vincent Setola, William C. Wetsel, Shane W Kaski, Allison N White, Kim Wix, Steven G. Kinsey, David P. Siderovski
Publikováno v:
J Psychopharmacol
Background:Regulator of G protein Signaling (RGS) proteins inhibit G protein-coupled receptor (GPCR) signaling, including the signals that arise from neurotransmitter release. We have shown that RGS12 loss diminishes locomotor responses of C57BL/6J m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c844739f06b5003b570f46e74ac023b2
https://doi.org/10.1177/0269881120944160
https://doi.org/10.1177/0269881120944160
Autor:
Aubrie A Harland, Steven G. Kinsey, Kim Wix, Shane W Kaski, Allison N White, Kristen R Trexler, Vincent Setola, Jeffrey Aubé, Terry P. Kenakin, David P. Siderovski, Joshua D Gross, Thomas E. Prisinzano
Publikováno v:
J Pharmacol Exp Ther
Mu opioid receptor (MOR)-targeting analgesics are efficacious pain treatments, but notorious for their abuse potential. In preclinical animal models, coadministration of traditional kappa opioid receptor (KOR)-targeting agonists with MOR-targeting an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590e1e6e2c01d88146faf230eeecacf0
https://doi.org/10.1124/jpet.118.255661
https://doi.org/10.1124/jpet.118.255661
Publikováno v:
Pharmacology Biochemistry and Behavior. 177:27-33
Recently, multiple compounds have been synthesized that target the allosteric binding site(s) of CB(1). These CB(1) positive allosteric modulators, may capture the benefits of cannabinoid receptor activation without unwanted psychoactive effects, suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698e62d3e2bacc20d67c853b6c0dd394
https://doi.org/10.1016/j.pbb.2018.12.009
https://doi.org/10.1016/j.pbb.2018.12.009
Publikováno v:
Pharmacol Biochem Behav
Withdrawal from Δ9-tetrahyrocannibidol (THC) is associated with a host of dysphoric symptoms that increase probability of relapse. To date, many animal models of THC withdrawal rely on withdrawal-induced somatic withdrawal signs leaving withdrawal-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0aa2e378742cac3bba618e19470ae4
https://europepmc.org/articles/PMC7415667/
https://europepmc.org/articles/PMC7415667/
Publikováno v:
Drug and alcohol dependence
Background Recent years have seen a rise in the diversity and use of synthetic cannabinoids. The present study evaluated the behavioral effects of the third-generation indazole-3-carboxamide-type synthetic cannabinoid, AB-FUBINACA. Methods Adult male
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3574fe1ce1c167a54951b59c3c52146
https://doi.org/10.1016/j.drugalcdep.2020.108179
https://doi.org/10.1016/j.drugalcdep.2020.108179
Autor:
Margaret S. Jones, Kristen R Trexler, Steven G. Kinsey, Joshua D Gross, Austin W. McKitrick, Molly S. Crowe, David P. Siderovski, Sara R. Nass
Background A subset of cannabis users develop some degree of Cannabis Use Disorder (CUD). Although behavioral therapy has some success in treating CUD, many users relapse, often citing altered sleep, mood, and irritability. Preclinical animal tests o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3698d7e4ac44f8100bd002ded70e593e
https://europepmc.org/articles/PMC6404969/
https://europepmc.org/articles/PMC6404969/