Zobrazeno 1 - 3
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pro vyhledávání: '"Kristen Przekop"'
Autor:
Timur I. Gaynutdinov, Joseph M. Backer, Mohamed Arab, Inna Gorshkova, Marina V. Backer, Tao Hu, Robert J. Crouch, Renee Aloise, Kristen Przekop
Publikováno v:
Journal of Controlled Release. 89:499-511
Targeted drug delivery requires ‘loading’ drugs onto targeting proteins. Traditional technologies for loading drugs rely on chemical conjugation of drugs or drug carriers to targeting proteins. An alternative approach might rely on assembly of ta
Publikováno v:
Protein Expression and Purification. 26:455-461
High affinity interaction between S-protein and S-peptide fragments of bovine pancreatic RNase A has been recently used for construction of molecular vehicles for targeted drug delivery. The vehicle is assembled as a complex of drug carrier conjugate
Publikováno v:
Bioconjugate Chemistry. 13:462-467
Targeted drug delivery by cell-specific cytokines and antibodies promises greater drug efficacy and reduced side effects. We describe a novel strategy for assembly of drug delivery vehicles that does not require chemical modification of targeting pro