Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Kristen O. Arseneau"'
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 1, Pp 19-32 (2017)
Crohnâs disease and ulcerative colitis, together known as inflammatory bowel disease, are debilitating chronic disorders of unknown cause and cure. Our evolving understanding of these pathologies is enhanced greatly by the use of animal models of in
Externí odkaz:
https://doaj.org/article/4c1673d185d1479d851ebb282c586605
Autor:
Fabio Cominelli, Theresa T. Pizarro, Kristen O. Arseneau, Wei Xin, Paola Menghini, Maneesh Dave, Luca Di Martino
This supplementary figure describes the effects of DSS administration in TWEAK deficient mice compared to wild type littermates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c33cdf061b1fbbf2a42c0b7f16817c5
https://doi.org/10.1158/0008-5472.22413072
https://doi.org/10.1158/0008-5472.22413072
Autor:
Fabio Cominelli, Theresa T. Pizarro, Kristen O. Arseneau, Wei Xin, Paola Menghini, Maneesh Dave, Luca Di Martino
Inflammatory bowel disease causes chronic, relapsing intestinal inflammation that can lead to the development of colorectal cancer. Members of the TNF superfamily are key regulators of intestinal inflammation. In particular, TNF-like weak inducer of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6bfe818d5395ab24afaec78b121e125
https://doi.org/10.1158/0008-5472.c.6508608.v1
https://doi.org/10.1158/0008-5472.c.6508608.v1
Autor:
Fabio Cominelli, Theresa T. Pizarro, Kristen O. Arseneau, Wei Xin, Paola Menghini, Maneesh Dave, Luca Di Martino
This supplementary figure describes the effects of Fn14 antibody neutralization in C57/BL6 mice following induction of DSS colitis..
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3096d43d9463c027b4e935a69e63221
https://doi.org/10.1158/0008-5472.22413069.v1
https://doi.org/10.1158/0008-5472.22413069.v1
Autor:
Daniele Corridoni, Luca Pastorelli, Benedetta Mattioli, Silviu Locovei, Dai Ishikawa, Kristen O Arseneau, Marcello Chieppa, Fabio Cominelli, Theresa T Pizarro
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42067 (2012)
We previously showed that the probiotic mixture, VSL#3, prevents the onset of ileitis in SAMP/YitFc (SAMP) mice, and this effect was associated with stimulation of epithelial-derived TNF. The aim of this study was to determine the mechanism(s) of VSL
Externí odkaz:
https://doaj.org/article/c6ac8cd501764245bb1be4bb7c853594
Autor:
Hiroshi Tamagawa, Alexander Rodriguez-Palacios, Carlo De Salvo, Fabio Cominelli, Li Guo Jia, Zhaodong Li, Kristen O. Arseneau, Theresa T. Pizarro, Ludovica F. Buttó, Giorgos Bamias
Publikováno v:
Inflammatory Bowel Diseases. 25:14-26
BACKGROUND: TNF-like cytokine 1A (TL1A) and its functional receptor, death-domain-receptor-3 (DR3), are multifunctional mediators of effector and regulatory immunity. We aimed to evaluate the functional role and therapeutic potential of TL1A/DR3 sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7121a2b325e5aea8c0c8f28bbb5f33e
https://doi.org/10.1093/ibd/izy305
https://doi.org/10.1093/ibd/izy305
Publikováno v:
Current Opinion in Gastroenterology. 33:411-416
Currently several mouse models are considered representative of inflammatory bowel disease (IBD). This review presents recent developments regarding the role of animal models of intestinal inflammation as research tools in IBD.Preclinical studies in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3cbdea3da18e3c55cd3e121a72531c7
https://doi.org/10.1097/mog.0000000000000402
https://doi.org/10.1097/mog.0000000000000402
Publikováno v:
Expert Opinion on Biological Therapy. :1-6
Amongst the available therapies for moderate to severe Crohn's disease (CD) patients who are refractory to conventional therapy, anti-TNF blockers are the most effective biological treatment option. However, many patients experience a primary or seco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bfc32c8ed560d22d84e68b03d2b31df
https://doi.org/10.1080/14712598.2017.1366444
https://doi.org/10.1080/14712598.2017.1366444
Autor:
Fabio Cominelli, Maneesh Dave, Wei Xin, Paola Menghini, Kristen O. Arseneau, Theresa T. Pizarro, Luca Di Martino
Publikováno v:
Cancer Research. 76:6533-6542
Inflammatory bowel disease causes chronic, relapsing intestinal inflammation that can lead to the development of colorectal cancer. Members of the TNF superfamily are key regulators of intestinal inflammation. In particular, TNF-like weak inducer of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c42c107a80a679382b1e3c3ec45a29
https://doi.org/10.1158/0008-5472.can-16-0400
https://doi.org/10.1158/0008-5472.can-16-0400
Autor:
Fabio Cominelli, Kristen O. Arseneau
Publikováno v:
Inflammatory bowel diseases. 23(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bbfbf0e4cf93c4546375ef6deaf5743
https://pubmed.ncbi.nlm.nih.gov/29135693
https://pubmed.ncbi.nlm.nih.gov/29135693