Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kristen O'Halloran Cardinal"'
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0217709 (2019)
ObjectiveIntravascular stents are commonly used to treat occluded arteries during coronary heart disease. After coronary stent implantation, endothelial cells grow over the stent, which is referred to as re-endothelialization. Re-endothelialization p
Externí odkaz:
https://doaj.org/article/f24af3ec9da2477abc8bff5cb16cd7c6
Autor:
Ryan Murphy, Leo Banuelos, Ashley Turcott, Evan Dowey, Benjamin Goodwin, Kristen O'Halloran Cardinal
Publikováno v:
Tissue Engineering. Part C, Methods
Quantifying fiber diameter is important for characterizing electrospun polymer scaffolds. Many researchers use manual measurement methods, which can be time-consuming and variable. Semi-automated tools exist, but there is room for improvement. The cu
Autor:
Gabriella Graham, Alyssa McCulloch, Ashley Turcott, Kristen O'Halloran Cardinal, Sergey Frenklakh
Publikováno v:
Journal of Neurointerventional Surgery
ObjectiveThe goal of this work was to endothelialize silicone aneurysm tubes for use as in vitro models for evaluating endothelial cell interactions with neurovascular devices. The first objective was to establish consistent and confluent endothelial
Autor:
Ramanathan Kadirvel, Yong Hong Ding, David F. Kallmes, Yang Liu, Daying Dai, Kristen Temnyk, Tiffany W. Shen, Kristen O'Halloran Cardinal, Wenjing Liu
Publikováno v:
J Neurointerv Surg
BackgroundNotwithstanding the widespread implementation of flow diverters (FDs) in the treatment of intracranial aneurysms, the exact mechanism of action of these devices remains elusive. We aimed to advance the understanding of cellular responses to
Autor:
Benjamin Dennis, Brandon Puccini, Camille Villadolid, Tessa Gunnin, Kristen O'Halloran Cardinal, Conor Hedigan
Publikováno v:
Journal of Materials Science. Materials in Medicine
Endovascular techniques for treating cerebral aneurysms are rapidly advancing and require testing to optimize device configurations. The purpose of this work was to customize tissue-engineered aneurysm “blood vessel mimics” (aBVMs) for early stag
Publikováno v:
Neuroradiology. 61(6)
Preclinical testing of neurovascular devices is crucial for successful device design and is commonly performed using in vivo organisms such as the rabbit elastase-induced aneurysm model; however, simple in vitro models may help further refine this te
Autor:
Duncan J. Maitland, Thomas S. Wilson, Todd L. Landsman, Sarah Ur, Landon D. Nash, Mark A. Wierzbicki, Alexander T. Lonnecker, Kristen O'Halloran Cardinal, Keith Hearon, Karen L. Wooley, Christine R. Laramy, Michael C. Gibbons
Publikováno v:
Advanced Healthcare Materials. 4:1386-1398
Polyurethane shape memory polymers (SMPs) with tunable thermomechanical properties and advanced processing capabilities are synthesized, characterized, and implemented in the design of a microactuator medical device prototype. The ability to manipula
Publikováno v:
Physics in Medicine and Biology. 53:3083-3098
Recent research has suggested that endothelialization of vascular stents is crucial to reducing the risk of late stent thrombosis. With a resolution of approximately 10 microm, optical coherence tomography (OCT) may be an appropriate imaging modality
Autor:
Garret T. Bonnema, Heidi Hofer, Jennifer K. Barton, Kristen O'Halloran Cardinal, Stuart K. Williams
Publikováno v:
Tissue Engineering. 12:3431-3438
The accelerating use of minimally invasive procedures for the treatment of cardiovascular disease, and the commensurate development of intravascular devices such as stents, has lead to a high demand for preclinical assessment techniques. A 3-dimensio
Thinking inside the box: keeping tissue-engineered constructs in vitro for use as preclinical models
Publikováno v:
Tissue engineering. Part B, Reviews. 19(1)
Tissue engineers have made great strides toward the creation of living tissue replacements for a wide range of tissue types and applications, with eventual patient implantation as the primary goal. However, an alternate use of tissue-engineered const