Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kristen Monte"'
Autor:
Marissa C. Locke, Kristen Monte, Lindsey E. Fox, Alissa R. Young, Bria F. Dunlap, Deborah J. Lenschow
Publikováno v:
J Virol
Chikungunya virus (CHIKV) is an arthritogenic alphavirus that causes both debilitating acute and chronic disease. Previous work has shown that type I interferons (IFNs) play a critical role in limiting CHIKV pathogenesis and that interferon alpha (IF
Autor:
Kristen Monte, L. David Sibley, Devesha H. Kulkarni, Jiani N. Chai, Jisun Jung, Georgia Wilke, Alec Wehmeier, Chyi-Song Hsieh, Bernd H. Zinselmeyer, Aidan T. Miller, Jaeu Yi, Vivek Durai, Rafael S. Czepielewski, Shannon Young, Suellen Greco, Kenneth M. Murphy, Lindsey E. Fox, Lisa J. Funkhouser-Jones, Rodney D. Newberry, Emilie V. Russler-Germain
Publikováno v:
Immunity. 54:2547-2564.e7
Summary Cryptosporidium can cause severe diarrhea and morbidity, but many infections are asymptomatic. Here, we studied the immune response to a commensal strain of Cryptosporidium tyzzeri (Ct-STL) serendipitously discovered when conventional type 1
Autor:
Raeann M. Shimak, Lindsey E. Cook, Matthew L. Hedberg, Kathleen C. F. Sheehan, Deborah J. Veis, Marissa C. Locke, Alissa R. Young, Deborah J. Lenschow, Michael S. Diamond, Kristen Monte
Publikováno v:
J Virol
Type I interferons (IFNs) are key mediators of the innate immune response. Although members of this family of cytokines signal through a single shared receptor, biochemical and functional variation exists in response to different IFN subtypes. While
Autor:
Daniel R. Perez, Irene Rodríguez-Sánchez, Kristen Monte, Deborah J. Lenschow, Luis Martinez-Sobrido, Aitor Nogales
Publikováno v:
Virus Research
Influenza B viruses (IBVs) cause annual outbreaks of respiratory illness in humans and are increasingly recognized as a major cause of influenza-associated morbidity and mortality. Studying influenza viruses requires the use of secondary methodologie
Autor:
Caleb D. Swaim, Jon M. Huibregtse, Swati Khanna, Deborah J. Lenschow, Kristen Monte, Larissa A. Canadeo
Publikováno v:
Cell Reports
Cell Reports, Vol 31, Iss 11, Pp 107772-(2020)
Cell Reports, Vol 31, Iss 11, Pp 107772-(2020)
Summary ISG15 is a ubiquitin-like modifier that also functions extracellularly, signaling through the LFA-1 integrin to promote interferon (IFN)-γ release from natural killer (NK) and T cells. The signals that lead to the production of extracellular
Publikováno v:
The Journal of Immunology. 204:171.6-171.6
Chikungunya virus (CHIKV) is an arthritogenic alphavirus that acutely causes fever as well as severe joint and muscle pain. Chronic musculoskeletal pain persists in a substantial fraction of patients for months to years after infection. While replica
Autor:
Jessica J. Struckhoff, Eugene Agapov, Thaddeus S. Stappenbeck, Lulu Sun, Michael J. Holtzman, Deborah J. Lenschow, Kristen Monte, David J. Morales
Publikováno v:
Journal of Virology. 89:337-349
ISG15 is a diubiquitin-like modifier and one of the most rapidly induced genes upon type I interferon stimulation. Hundreds of host proteins and a number of viral proteins have been shown to be ISGylated, and understanding how these modifications aff
Autor:
Anjali Rohatgi, Gabrielle Kardon, Deborah J. Lenschow, Joseph C. Corbo, Kristen Monte, Stephen Higgs, Dana L. Vanlandingham
Publikováno v:
Journal of Virology. 88:2414-2425
Chikungunya virus (CHIKV) is an alphavirus transmitted by mosquitoes that is known to cause severe arthritis and myositis in affected patients. The ongoing epidemic began in eastern Africa in 2004 and then spread to islands of the Indian Ocean, India
Autor:
Marina Cella, Kristen Monte, Yina H. Huang, Deborah J. Lenschow, Olga Y. Lubman, Daved H. Fremont, Xinxin Wang
Publikováno v:
Journal of Virology. 88:538-546
Viruses have long been studied not only for their pathology and associated disease but also as model systems for understanding cellular and immunological processes. Rodent herpesvirus Peru (RHVP) is a recently characterized rhadinovirus related to mu
Autor:
Matthew L. Hedberg, Deborah J. Lenschow, Bradley E. Hiller, Lindsey E. Cook, Marissa C. Locke, Kristen Monte, Michael S. Diamond, Deborah J. Veis, Alissa R. Young, Rong Zhang
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 15, Iss 8, p e1007993 (2019)
PLoS Pathogens, Vol 15, Iss 8, p e1007993 (2019)
Chikungunya virus (CHIKV) is an arthritogenic alphavirus that acutely causes fever as well as severe joint and muscle pain. Chronic musculoskeletal pain persists in a substantial fraction of patients for months to years after the initial infection, y