Výsledky vyhledávání - "Kristen Metzler"

Effect of reflex and mechanical decreases in skin perfusion on thermal- and agonist-induced eccrine sweating in humans

Autor: Kristen Metzler-Wilson, Milie M. Fang, Kenan Alibegovic, James W. Daggett, Seetharam C. Narra, Robert P. Dazé, Olivia G. Miller, Thad E. Wilson

Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 324:R271-R280

In humans, skin blood flux (SkBF) and eccrine sweating are tightly coupled, suggesting common neural control and regulation. This study was designed to separate these two sympathetic nervous system end-organ responses via nonadrenergic SkBF-decreasin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f332d78a0dcecf9e90ca7ab6e44fd4eb
https://doi.org/10.1152/ajpregu.00066.2022

Zobrazit plný text záznamu

Regional Differences in Human Skin Responses to Receptor Agonists: Implications for Differing Facial vs. Forearm Innervation

Autor: C. Ilinca Ungureanu, Stout Stout, Olivia G. Miller, Kristen Metzler-Wilson

Publikováno v: Proceedings of IMPRS. 5

There is not yet consensus on the precise differences between non-glabrous and facial skin characteristics. Our lab identified similar responses to local heat stress in forearm and facial skin, while others identified differing responses to autonomic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3280b40b385eeae23fb2b5d7ef8c6e42
https://doi.org/10.18060/26749

Zobrazit plný text záznamu

Cutaneous iontophoresis of adrenergic agonists can mimic in vivo neural effects on vasodilation

Autor: John A. Stout, C. Ilinca Ungureanu C. Ilinca Ungureanu, Olivia G. Miller, Kristen Metzler-Wilson

Publikováno v: Proceedings of IMPRS. 5

Iontophoresis utilizes electrical current to non-invasively deliver agents through the skin. This pilot study sought to determine if iontophoresis could be paired with laser Doppler flowmetry (LDF) to administer adrenergic and cholinergic agonists an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::71c069f2f7497d287e30af0218c2e949
https://doi.org/10.18060/26810

Zobrazit plný text záznamu

Abstract 4094: Enhanced CRISPR-Cas9 edited CAR-T cells through simultaneous inactivation of multiple T cell exhaustion pathways

Autor: Oksana Sergeeva, Amber Fearnley, Shu Shien Chin, Xingyue An, Nana Adjoa Pels, Kristen Metzler, Kyla Joinville, Lizet Aquino Calderon, Abudukadier Abulizi, Hayden Karp, Julio Rodriguez, Louis Matis, Jay Fine, Jeremy Myers

Publikováno v: Cancer Research. 83:4094-4094

T cell exhaustion is a hallmark of tumor-infiltrating T cells and a major therapeutic challenge for immunotherapy which is not sufficiently understood. To identify T cell exhaustion promoting genes which may be targeted by new therapies, we combined

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1d15c5848f31bc4343d2389a871d5b8c
https://doi.org/10.1158/1538-7445.am2023-4094

Zobrazit plný text záznamu

Effect of Suboccipital Release on Pain Perception and Autonomic Reflex Responses to Ischemic and Cold Pain

Autor: Abby Vrable, Benjamin V Rodimel, B. Andrew Krause, Trenton K Schmale, Thad E. Wilson, Kristen Metzler-Wilson, Andrew Schaub

Publikováno v: Pain Med

Objective/Subjects To determine the autonomic effects of suboccipital release (SOR) during experimentally induced pain, 16 healthy subjects (eight women, eight men) experienced ischemic (forearm postexercise muscle ischemia [PEMI]) and cold (cold pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b83e0f4798b75eabf9b70bca068eb2
https://doi.org/10.1093/pm/pnaa051

Zobrazit plný text záznamu

Role of bradykinin type 2 receptors in human sweat secretion: translational evidence does not support a functional relationship

Autor: Kristen Metzler-Wilson, Artur Schneider, Kelsey A. Bullens, Thad E. Wilson, Ian S. Holt, Seetharam Narra

Publikováno v: Skin Pharmacol Physiol

Bradykinin increases skin blood flow via a cGMP mechanism but its role in sweating in vivo is unclear. There is a current need to translate cell culture and nonhuman paw pad studies into in vivo human preparations to test for therapeutic viability fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1f0d3b24312dac9d73f6abc14a7afa
https://europepmc.org/articles/PMC10246487/

Zobrazit plný text záznamu

Role of bradykinin type 2 receptors in human sweat secretion: translational evidence does not support a functional relationship

Autor: Artur Schneider, Ian S. Holt, Kelsey A. Bullens, Thad E. Wilson, Seetharam Narra, Kristen Metzler-Wilson

Bradykinin increases skin blood flow via a cGMP mechanism but its role in sweating in vivo is unclear. There is a current need to translate cell culture and non-human paw pad studies into in vivo human preparations to test for therapeutic viability f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8cda34b5ed497b7b0e95b95bb031647
https://doi.org/10.1101/2020.12.01.407114

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání