Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kristen Meckel"'
Autor:
Ajay N. Jain, Drew M. Pardoll, Kristen Meckel, John M. Thompson, Kiyoshi Yoshimura, Richard D. Schulick, Jill E. Slansky, Lindsay S. Laird, Christina Y. Chia
Publikováno v:
Cancer Research. 67:10058-10066
The liver represents a major and frequently sole site of metastases for many types of cancer, particularly gastrointestinal cancers. We showed previously that coadministration of an engineered hepatic-targeting Listeria monocytogenes (LM) with a canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318f60305c12ec377f9a255788caca5c
https://doi.org/10.1158/0008-5472.can-07-0573
https://doi.org/10.1158/0008-5472.can-07-0573
Autor:
Walter P. Weber, Avesh Thuluvath, Kelly Olino, Barish H. Edil, Richard D. Schulick, Xiaoyu Pan, Kristen Meckel, Kiyoshi Yoshimura, Drew M. Pardoll
Publikováno v:
Archives of Surgery. 147
Previous work demonstrated that a subset of natural killer T cells in mice decreased the antitumor efficacy of live attenuated Listeria monocytogenes where the actin A and internalin B genes were genetically deleted (LMD) against murine hepatic color
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922bb905d178855aceee38b55bb1b0f1
https://doi.org/10.1001/archsurg.2011.2206
https://doi.org/10.1001/archsurg.2011.2206
Autor:
Jill E. Slansky, Kristen Meckel, Xiaoyu Pan, Barish H. Edil, Kelly Olino, Drew M. Pardoll, Satoshi Wada, Peter Lauer, Richard D. Schulick, Koji Tamada, Dirk G. Brockstedt, Kiyoshi Yoshimura, Walter P. Weber
Publikováno v:
Annals of Surgical Oncology
Purpose Despite advances in therapy for the treatment of metastatic colorectal cancer, many patients die of hepatic disease. Current immunotherapeutic strategies are likely limited by inhibitory signals from the tumor. To successfully eliminate tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dfba35d6aa36fdc922bc810e6cf3935
https://pubmed.ncbi.nlm.nih.gov/21979110
https://pubmed.ncbi.nlm.nih.gov/21979110
Autor:
Norio Iizuka, Jesse W. Keller, Kelly Olino, Yukihiko Kato, Masaaki Oka, Fumin Chang, Lewis H. Romer, Shoichi Hazama, Kristen Meckel, Richard D. Schulick, Drew M. Pardoll, Jang-June Park, Christine A. Iacobuzio-Donahue, John M. Thompson, Kiyoshi Yoshimura, Ryouichi Tsunedomi, Lindsay S. Laird, Ajay N. Jain, Toshio Harada, Christina Y. Chia
Cancers display distinct patterns of organ-specific metastasis. Comparative analysis of a broad array of cell membrane molecules on a liver-metastasizing subline of B16 melanoma versus the parental B16-F0 revealed unique up-regulation of integrin α2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a4a29137361d66147482bd04877c4f
https://europepmc.org/articles/PMC4857201/
https://europepmc.org/articles/PMC4857201/
Autor:
Wayne M. Koch, Paolo Serafini, Joseph A. Califano, Kimberly A. Noonan, Kristen Meckel, Michael Kelso, Ivan Borrello, Luigi Dolcetti, Vincenzo Bronte
Publikováno v:
The Journal of Experimental Medicine
Phosphodiesterase-5 (PDE5) inhibitors (sildenafil, tadalafil, and vardenafil) are agents currently in clinical use for nonmalignant conditions. We report the use of PDE5 inhibitors as modulators of the antitumor immune response. In several mouse tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b18524522ea807bdde1c6e42604f779
http://hdl.handle.net/11562/347686
http://hdl.handle.net/11562/347686
Autor:
Kelly Olino, Satoshi Wada, Xiaoyu Pan, Walter P. Weber, Richard D. Schulick, Tsuyoshi Mori, Kristen Meckel, Drew M. Pardoll, Barish H. Edil, Kiyoshi Yoshimura, Saraswati Sukumar
Publikováno v:
Cancer Research. 71:LB-456
Chemotherapy has been shown to act as an immune response modifier. Many groups, incuding our own, are using chemotherapy to induce immune responses such as by using low doses of cyclophosphamide. Our previous work has demonstrated that anti-cancer ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5477d7dd0aaf478d2d23c5895123b55
https://doi.org/10.1158/1538-7445.am2011-lb-456
https://doi.org/10.1158/1538-7445.am2011-lb-456
Autor:
Mark Bonyhadi, Paolo Serafini, Ivan Borrello, Stephanie Mgebroff, Kristen Meckel, Kimberly A. Noonan
Publikováno v:
Blood. 108:1741-1741
We have previously shown that marrow infiltrating lymphocytes (MILs) from myeloma patients proliferate upon stimulation with anti-CD3/CD28 beads more efficiently and exhibit greater specificity to autologous tumor than their peripheral blood lymphocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e22510b7bcf957b072fd5ddb49951d48
https://doi.org/10.1182/blood.v108.11.1741.1741
https://doi.org/10.1182/blood.v108.11.1741.1741