Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Kristen M. Seiler"'
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Akademický článek
Single-Cell Analysis Reveals Regional Reprogramming During Adaptation to Massive Small Bowel Resection in MiceSummary
Autor: Kristen M. Seiler, Sarah E. Waye, Wenjun Kong, Kenji Kamimoto, Adam Bajinting, William H. Goo, Emily J. Onufer, Cathleen Courtney, Jun Guo, Brad W. Warner, Samantha A. Morris
Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 3, Pp 407-426 (2019)
Background & Aims: The small intestine (SI) displays regionality in nutrient and immunological function. Following SI tissue loss (as occurs in short gut syndrome, or SGS), remaining SI must compensate, or “adapt”; the capacity of SI epithelium t
Externí odkaz: https://doaj.org/article/f1b4e01318da43e0baba97df780a42b8
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2
Akademický článek
Side population sorting separates subfractions of cycling and non-cycling intestinal stem cells
Autor: Richard J. von Furstenberg, Simon J.A. Buczacki, Brian J. Smith, Kristen M. Seiler, Douglas J. Winton, Susan J. Henning
Publikováno v: Stem Cell Research, Vol 12, Iss 2, Pp 364-375 (2014)
We report here that side population (SP) sorting allows for the simultaneous isolation of two intestinal stem cell (ISC) subsets from wild-type (WT) mice which are phenotypically different and represent cycling and non-cycling pools of cells. Followi
Externí odkaz: https://doaj.org/article/a3ad3928bf424772aa8adad1909d74fa
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3
Small Bowel Resection Increases Paracellular Gut Barrier Permeability via Alterations of Tight Junction Complexes Mediated by Intestinal TLR4
Autor: Brad W. Warner, Maria E. Tecos, Cathleen M. Courtney, Rodney D. Newberry, Keely G. McDonald, Anne M. Sescleifer, Emily J. Onufer, Kristen M. Seiler, Allie E. Steinberger
Publikováno v: J Surg Res
BACKGROUND: Short bowel syndrome resulting from small bowel resection (SBR) is associated with significant morbidity and mortality. Many adverse sequelae including steatohepatitis and bacterial overgrowth are thought to be related to increased bacter
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91bed5e915b7f4eb80c41200bae4c2b1
https://doi.org/10.1016/j.jss.2020.08.049
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4
Are surgeons behind the scientific eight ball: Delayed acquisition of the NIH K08 mentored career development award
Autor: Kristen M. Seiler, Brian D. Hosfield, Troy A. Markel, Misty Good, Gary L. Dunnington, Quincy E. John
Publikováno v: Am J Surg
BACKGROUND: Surgery residents complete their research training early in residency. Non-surgical trainees typically have research incorporated toward the last two years of their fellowship, conferring an advantage to apply for grants with recent resea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42fca378d2a5d478fb849e281c4c2c6b
https://doi.org/10.1016/j.amjsurg.2019.11.039
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6
Single-Cell Analysis Reveals Regional Reprogramming During Adaptation to Massive Small Bowel Resection in Mice
Autor: Kenji Kamimoto, Samantha A. Morris, Brad W. Warner, Cathleen M. Courtney, Wenjun Kong, William H. Goo, Sarah E. Waye, Kristen M. Seiler, Adam Bajinting, Jun Guo, Emily J. Onufer
Publikováno v: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 3, Pp 407-426 (2019)
Background & Aims The small intestine (SI) displays regionality in nutrient and immunological function. Following SI tissue loss (as occurs in short gut syndrome, or SGS), remaining SI must compensate, or “adapt”; the capacity of SI epithelium to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee63d6c1e370ac6859fe49b3aee2f738
http://europepmc.org/articles/PMC6718927
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7
EGFR in enterocytes & endothelium and HIF1α in enterocytes are dispensable for massive small bowel resection induced angiogenesis
Autor: Kristen M. Seiler, Jun Guo, Lihong V. Wang, Aiza Bustos, Adam Bajinting, Toru Imai, Stephanie Sutton, Emily J. Onufer, Anne M. Sescleifer, Brad W. Warner, Chenghung Yeh, Cathleen M. Courtney, Bola Aladegbami, Junjie Yao
Publikováno v: PLoS ONE, Vol 15, Iss 9, p e0236964 (2020)
PLoS ONE
BackgroundShort bowel syndrome (SBS) results from significant loss of small intestinal length. In response to this loss, adaptation occurs, with Epidermal Growth Factor Receptor (EGFR) being a key driver. Besides enhanced enterocyte proliferation, we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5aaeade46019cc1f5bb7ed97ae4c111
https://resolver.caltech.edu/CaltechAUTHORS:20200923-104855183
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9
Lymphatic network remodeling after small bowel resection
Autor: Cathleen M. Courtney, Gwendalyn J. Randolph, Kristen M. Seiler, Brad W. Warner, Emily J. Onufer, Aiza Bustos, Emma C. Erlich, Rafael S. Czepielewski
Publikováno v: J Pediatr Surg
Background Short gut syndrome (SGS) following massive small bowel resection (SBR) is a major cause of pediatric mortality and morbidity secondary to nutritional deficiencies and the sequelae of chronic total parenteral nutrition use, including liver
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ecc1063de6875022c496601986b728
https://pubmed.ncbi.nlm.nih.gov/30879758
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