Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kristen M. Rauwerdink"'
Autor:
Emmanuel S, Buys, Michael J, Raher, Andrew, Kirby, Mohd, Shahid, Shahid, Mohd, David M, Baron, Sarah R, Hayton, Laurel T, Tainsh, Patrick Y, Sips, Kristen M, Rauwerdink, Qingshang, Yan, Robert E T, Tainsh, Hannah R, Shakartzi, Christine, Stevens, Kelly, Decaluwé, Maria da Gloria, Rodrigues-Machado, Rajeev, Malhotra, Johan, Van de Voorde, Tong, Wang, Peter, Brouckaert, Mark J, Daly, Kenneth D, Bloch
Publikováno v:
JOURNAL OF CLINICAL INVESTIGATION
Nitric oxide (NO) plays an essential role in regulating hypertension and blood flow by inducing relaxation of vascular smooth muscle. Male mice deficient in a NO receptor component, the α1 subunit of soluble guanylate cyclase (sGCα1), are prone to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61cbd439fede3535473e09dd0bf9bb2d
https://doi.org/10.1172/jci60119
https://doi.org/10.1172/jci60119
Autor:
Rushdia Z. Yusuf, Kristen M. Rauwerdink, Ashley J. Vonner, Julia C. Winn, Cindy N. Roy, Jasbir Seehra, Paul B. Yu, Borja Saez, Carol S. Lai, Donna Y. Deng, Chetana Sachidanandan, Gregory D. Cuny, Andrea U. Steinbicker, Colleen Cook, Brian A. Szekely, Randall T. Peterson, David T. Scadden, Kenneth D. Bloch
Publikováno v:
Blood. 117:4915-4923
Anemia of inflammation develops in settings of chronic inflammatory, infectious, or neoplastic disease. In this highly prevalent form of anemia, inflammatory cytokines, including IL-6, stimulate hepatic expression of hepcidin, which negatively regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6005d6e32757f9a2be953d157dea2c
https://doi.org/10.1182/blood-2010-10-313064
https://doi.org/10.1182/blood-2010-10-313064
Autor:
Kristen M. Rauwerdink, Peter Brouckaert, Ester Spagnolli, Yasuko Nagasaka, Kenneth D. Bloch, Andrea U. Steinbicker, Sarah R Hayton, Warren M. Zapol, Emmanuel S. Buys
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 300:H1477-H1483
Reperfusion injury limits the benefits of revascularization in the treatment of myocardial infarction (MI). Breathing nitric oxide (NO) reduces cardiac ischemia-reperfusion injury in animal models; however, the signaling pathways by which inhaled NO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c84e96f0c4704c4cf8d20baf7a4d7dd
https://doi.org/10.1152/ajpheart.00948.2010
https://doi.org/10.1152/ajpheart.00948.2010
Autor:
Michael A. Moskowitz, Kristen M. Rauwerdink, Peter Brouckaert, Izumi Yuzawa, Kenneth D. Bloch, Rajeev Malhotra, Junlei Chang, Cenk Ayata, Dmitriy N. Atochin, Qian Li, Paul L. Huang, Emmanuel S. Buys
Publikováno v:
Stroke. 41:1815-1819
Background and Purpose— Nitric oxide mediates endothelium-dependent vasodilation, modulates cerebral blood flow, and determines stroke outcome. Nitric oxide signals in part by stimulating soluble guanylate cyclase (sGC) to synthesize cGMP. To study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5ace4aa00e500ad3ce592c3d193723
https://doi.org/10.1161/strokeaha.109.577635
https://doi.org/10.1161/strokeaha.109.577635
Publikováno v:
Biomedizinische Technik. Biomedical engineering. 58(6)
The rigidity of the extracellular matrix and of the integrin links to the cytoskeleton regulates signaling cascades, controlling critical aspects of cancer progression including metastasis and angiogenesis. We demonstrate that the matrix stiffness ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2dd2ee25b2c8ae69d057cfff5701d2
https://pubmed.ncbi.nlm.nih.gov/23945110
https://pubmed.ncbi.nlm.nih.gov/23945110
Autor:
Ion A. Hobai, Helene Thibault, Sharon M. Cawley, Emmanuel S. Buys, Peter Brouckaert, Robrecht Thoonen, Anje Cauwels, Marielle Scherrer-Crosbie, Kristen M. Rauwerdink, Kenneth D. Bloch, Patrick Sips, Jonathan J. Passeri, Fumito Ichinose, Michael J. Raher
Publikováno v:
BMC Pharmacology
Altered cGMP signaling has been implicated in myocardial depression, morbidity, and mortality associated with sepsis. Previous studies, using inhibitors of soluble guanylate cyclase (sGC), suggested that cGMP generated by sGC contributed to the cardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dfce50c07a4787b286fee27da237009
https://europepmc.org/articles/PMC2724210/
https://europepmc.org/articles/PMC2724210/
Autor:
Hannah R. Shakartzi, Patrick Sips, Christine Stevens, Kristen M. Rauwerdink, Kenneth D. Bloch, David M. Baron, Peter Brouckaert, Andrew Kirby, Mark J. Daly, Kelly Decaluwé, Laurel T. Tainsh, Shahid Mohd, Michael J. Raher, Emmanuel S. Buys, Sarah R Hayton, Maria da Glória Rodrigues-Machado, Johan Van de Voorde, Robert E. Tainsh, Rajeev Malhotra, Tong Wang
Publikováno v:
Nitric Oxide. 27:S25-S26
Male mice deficient in the α1 subunit of soluble guanylate cyclase, a nitric oxide (NO) receptor, are hypertensive when on a 129S6 (S6) background (sGC α 1 - / - S 6 ) but not when on a C57BL/6 (B6) background (sGC α 1 - / - B 6 ) , suggesting tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4970ef67153c159901c884ccf35e1014
https://doi.org/10.1016/j.niox.2012.04.093
https://doi.org/10.1016/j.niox.2012.04.093