Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kristen M. John"'
Autor:
Joseph D. Mancias, Andrew J. Aguirre, Jonathan A. Nowak, Yatrik M. Shah, Annan Yang, Wesley Huang, Connor J. Hennessey, Kristen E. Lowder, Nupur K. Das, Brandon Chen, Douglas E. Biancur, Kristen M. John, Miljan Kuljanin, Clara Poupault, Callum Malcolm, Ajami Gikandi, Huan Zhang, Kevin S. Kapner, Maria Quiles del Rey, Naiara Santana-Codina
Pancreatic ductal adenocarcinomas (PDAC) depend on autophagy for survival; however, the metabolic substrates that autophagy provides to drive PDAC progression are unclear. Ferritin, the cellular iron storage complex, is targeted for lysosomal degrada
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df60a8a731a7a45f287ddffb872e481
https://doi.org/10.1158/2159-8290.c.6549554
https://doi.org/10.1158/2159-8290.c.6549554
Autor:
Joseph D. Mancias, Andrew J. Aguirre, Jonathan A. Nowak, Yatrik M. Shah, Annan Yang, Wesley Huang, Connor J. Hennessey, Kristen E. Lowder, Nupur K. Das, Brandon Chen, Douglas E. Biancur, Kristen M. John, Miljan Kuljanin, Clara Poupault, Callum Malcolm, Ajami Gikandi, Huan Zhang, Kevin S. Kapner, Maria Quiles del Rey, Naiara Santana-Codina
Supplementary Figure from NCOA4-Mediated Ferritinophagy Is a Pancreatic Cancer Dependency via Maintenance of Iron Bioavailability for Iron–Sulfur Cluster Proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec2530edbf335fd3e84ebbf22ef7855
https://doi.org/10.1158/2159-8290.22541114.v1
https://doi.org/10.1158/2159-8290.22541114.v1
Autor:
Joseph D. Mancias, Andrew J. Aguirre, Jonathan A. Nowak, Yatrik M. Shah, Annan Yang, Wesley Huang, Connor J. Hennessey, Kristen E. Lowder, Nupur K. Das, Brandon Chen, Douglas E. Biancur, Kristen M. John, Miljan Kuljanin, Clara Poupault, Callum Malcolm, Ajami Gikandi, Huan Zhang, Kevin S. Kapner, Maria Quiles del Rey, Naiara Santana-Codina
Supplementary Table from NCOA4-Mediated Ferritinophagy Is a Pancreatic Cancer Dependency via Maintenance of Iron Bioavailability for Iron–Sulfur Cluster Proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f80b119732fbb4d264cc3dde406760
https://doi.org/10.1158/2159-8290.22541111
https://doi.org/10.1158/2159-8290.22541111
Autor:
Joseph D. Mancias, Andrew J. Aguirre, Jonathan A. Nowak, Yatrik M. Shah, Annan Yang, Wesley Huang, Connor J. Hennessey, Kristen E. Lowder, Nupur K. Das, Brandon Chen, Douglas E. Biancur, Kristen M. John, Miljan Kuljanin, Clara Poupault, Callum Malcolm, Ajami Gikandi, Huan Zhang, Kevin S. Kapner, Maria Quiles del Rey, Naiara Santana-Codina
Supplementary Data from NCOA4-Mediated Ferritinophagy Is a Pancreatic Cancer Dependency via Maintenance of Iron Bioavailability for Iron–Sulfur Cluster Proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d1264c8cea10a6bc8d55540c0b04d9
https://doi.org/10.1158/2159-8290.22541117.v1
https://doi.org/10.1158/2159-8290.22541117.v1
Autor:
Naiara Santana-Codina, Maria Quiles del Rey, Kevin S. Kapner, Huan Zhang, Ajami Gikandi, Callum Malcolm, Clara Poupault, Miljan Kuljanin, Kristen M. John, Douglas E. Biancur, Brandon Chen, Nupur K. Das, Kristen E. Lowder, Connor J. Hennessey, Wesley Huang, Annan Yang, Yatrik M. Shah, Jonathan A. Nowak, Andrew J. Aguirre, Joseph D. Mancias
Publikováno v:
Cancer Discov
Pancreatic ductal adenocarcinomas (PDAC) depend on autophagy for survival; however, the metabolic substrates that autophagy provides to drive PDAC progression are unclear. Ferritin, the cellular iron storage complex, is targeted for lysosomal degrada
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ce98a0377ced9d738825fd338101f7
https://europepmc.org/articles/PMC9437572/
https://europepmc.org/articles/PMC9437572/
Publikováno v:
Journal of Clinical Oncology. 41:666-666
666 Background: Individuals with cancer are more likely to visit an emergency department (ED) for issues both related and unrelated to their cancer than individuals without cancer, but data are lacking regarding what subpopulations are most vulnerabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38e0ec9427cc3d80dbc3ad5997231baa
https://doi.org/10.1200/jco.2023.41.4_suppl.666
https://doi.org/10.1200/jco.2023.41.4_suppl.666
Autor:
Kristen M. John, Joan C. Smith, Monet Lou Yuan, Erin L. Sausville, Jason M. Sheltzer, Vishruth Girish
The factors mediating fatal SARS-CoV-2 infections are poorly understood. Here, we show that cigarette smoke causes a dose-dependent upregulation of Angiotensin Converting Enzyme 2 (ACE2), the SARS-CoV-2 receptor, in rodent and human lungs. Using sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc238e82843986dc36b900d29da97168
Autor:
Jason M. Sheltzer, Vishruth Girish, Joan C. Smith, Monet Lou Yuan, Anand Vasudevan, Erin L. Sausville, Kristen M. John
Publikováno v:
Developmental Cell
The factors mediating fatal SARS-CoV-2 infections are poorly understood. Here, we show that cigarette smoke causes a dose-dependent upregulation of Angiotensin Converting Enzyme 2 (ACE2), the SARS-CoV-2 receptor, in rodent and human lungs. Using sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6532ebba046677d274094c4f3ce940ff
https://pubmed.ncbi.nlm.nih.gov/32425701
https://pubmed.ncbi.nlm.nih.gov/32425701
Autor:
Zachary C. Galluzzo, Ann Lin, Christopher J. Giuliano, Jason M. Sheltzer, Connor Abramowicz, Luwei Liu, Alexander R. Chait, Erin L. Sausville, Kristen M. John, Ann C. Palladino, Devon A. Lukow, Clara Tucker, Monet Lou Yuan
Publikováno v:
Sci Transl Med
Ninety-seven percent of drug-indication pairs that are tested in clinical trials in oncology never advance to receive U.S. Food and Drug Administration approval. While lack of efficacy and dose-limiting toxicities are the most common causes of trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601dae8a25111fc2527d4f970c618ff8
https://doi.org/10.1126/scitranslmed.aaw8412
https://doi.org/10.1126/scitranslmed.aaw8412
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::853db2872c38c7cdc7f3a72b71f6ab63
https://doi.org/10.1096/fasebj.2020.34.s1.05480
https://doi.org/10.1096/fasebj.2020.34.s1.05480