CARHSP1 is required for effective tumor necrosis factor alpha mRNA stabilization and localizes to processing bodies and exosomes

Autor: Kristen M. Deleault, Jason R. Pfeiffer, Ryan E. Fecteau, Bethany L. McAvoy, Seth A. Brooks

Publikováno v: Molecular and cellular biology. 31(2)

Tumor necrosis factor alpha (TNF-α) is a critical mediator of inflammation, and its production is tightly regulated, with control points operating at nearly every step of its biosynthesis. We sought to identify uncharacterized TNF-α 3' untranslated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b1b7d828b00f83a12191a13e658d9e
https://pubmed.ncbi.nlm.nih.gov/21078874

Extracellular signal-regulated kinase regulation of tumor necrosis factor-alpha mRNA nucleocytoplasmic transport requires TAP-NxT1 binding and the AU-rich element

Autor: Seth A. Brooks, Kristen M. Deleault, Ryan E. Fecteau, Stephen J. Skinner

Publikováno v: The Journal of biological chemistry. 283(6)

Tumor necrosis factor-alpha (TNF-alpha) production is regulated by transcriptional and posttranscriptional mechanisms. Lipopolysaccharide activates the NFkappaB pathway increasing TNF-alpha transcription. Lipopolysaccharide also activates the mitogen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::781420c2350d751ed93f13d960c12b71
https://pubmed.ncbi.nlm.nih.gov/18048358

High level secretion of cellobiohydrolases by Saccharomyces cerevisiae

Autor: Allan Froehlich, Kristen M. Deleault, Sanni Voutilainen, Elena E. Brevnova, Matti Siika-aho, Simon Ahlgren, Merja Penttilä, Marja Ilmen, John Mcbride, Willem H. van Zyl, Vineet Rajgarhia, Anu Koivula, Riaan den Haan, Naomi Thorngren, Mark T. Mellon, Daniel C. la Grange, Erin Wiswall

Publikováno v: Biotechnology for Biofuels
Biotechnology for Biofuels, Vol 4, Iss 1, p 30 (2011)
Ilmén, M, Den Haan, R, Brevnova, E, McBride, J, Wiswall, E, Froehlich, A, Koivula, A, Voutilainen, S P, Siika-Aho, M, La Grange, D C, Thorngren, N, Ahlgren, S, Mellon, M, Deleault, K, Rajgarhia, V, Van Zyl, W H & Penttilä, M 2011, ' High level secretion of cellobiohydrolases by Saccharomyces cerevisiae ', Biotechnology for Biofuels, vol. 4, 30 . https://doi.org/10.1186/1754-6834-4-30

Background The main technological impediment to widespread utilization of lignocellulose for the production of fuels and chemicals is the lack of low-cost technologies to overcome its recalcitrance. Organisms that hydrolyze lignocellulose and produce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab8aa3c5b739a0979a8ff239c0be2cc
http://europepmc.org/articles/PMC3224389