Výsledky vyhledávání - "Kristen Lemerise"

Activation of rat macrophages by Betafectin PGG-glucan requires cross-linking of membrane receptors distinct from complement receptor three (CR3)

Autor: William M. Mackin, Michael T Michalek, Kristen Lemerise, William Galbraith, David Melican, Myra L. Patchen, Matthew Langevin, Deborah Brunke-Reese

Publikováno v: Journal of leukocyte biology. 64(3)

PGG-glucan (Betafectin ) is a soluble, highly purified yeast (1,3)-β-glucan with broad anti-infective and immunomodulatory activities. These studies evaluated the ability of PGG-glucan to directly elicit O2– and tumor necrosis factor α (TNF-α) p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f01641e123b518b14b006ca619ce3a8d
https://pubmed.ncbi.nlm.nih.gov/9738660

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The Cytosolic Endopeptidase, Thimet Oligopeptidase, Destroys Antigenic Peptides and Limits the Extent of MHC Class I Antigen Presentation

Autor: Wanyong Zeng, Ian A. York, Annie X. Y. Mo, Kristen Lemerise, Kenneth L. Rock, Carmela R. Abraham, Tomo Saric, Yuelei Shen, Alfred L. Goldberg

Publikováno v: Immunity. (3):429-440

Most antigenic peptides presented on MHC class I molecules are generated by proteasomes during protein breakdown. It is unknown whether these peptides are protected from destruction by cytosolic peptidases. In cytosolic extracts, most antigenic pepti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdc91e33250affefd18fe8a77993c2cb

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