Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kristen Lauing"'
Autor:
Teresa Nguyen, Dong Ho Shin, Sagar Sohoni, Sanjay Singh, Yisel Rivera-Molina, Hong Jiang, Xuejun Fan, Joy Gumin, Frederick Lang, Christopher Alvarez-Breckenridge, Filipa Godoy-Vitorino, Lijie Zhai, Erik Ladomersky, Kristen Lauing, Marta Alonso, Derek Wainwright, Candelaria Gomez-Manzano, Juan Fueyo
Immune-related therapies have revolutionized the management of cancer. Oncolytic viruses are now considered part of the immunotherapy armamentarium and have shown promise in clinical trials of patients with glioblastoma. These studies have suggested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d09d5d7dc07f5061a881064c5ae4616
https://doi.org/10.21203/rs.3.rs-1079989/v1
https://doi.org/10.21203/rs.3.rs-1079989/v1
Autor:
April Bell, Margaret Johnson, Erik Ladomersky, Miri Kim, Junfei Zhao, Jason Miska, Lijie Zhai, Kristen Lauing, Evridiki Asimakidou, Prashant Bommi, James Chandler, Xinlei Mi, Masha Kocherginski, Rimas Lukas, Derek Wainwright
Publikováno v:
Neuro-Oncology. 24:vii274-vii274
OBJECTIVE The median age of onset for glioblastoma (GBM; IDHwt) is 68-70 years. Age is a strong prognostic factor for GBM patient outcomes such that overall survival in older adults is less than their younger counterparts – even after adjustment fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e90986fedb2ac5f63c23f2b0fc9e37e8
https://doi.org/10.1093/neuonc/noac209.1059
https://doi.org/10.1093/neuonc/noac209.1059
Autor:
Prashant Bommi, Paige Monsen, Lakshmi Bommi, Lijie Zhai, April Bell, Kristen Lauing, Xinlei Mi, Masha Kocherginski, Craig Horbinski, Rimas Lukas, Gary Schiltz, Derek Wainwright
Publikováno v:
Neuro-Oncology. 24:vii28-vii28
INTRODUCTION Indoleamine 2,3-dioxygenase 1 (IDO) is an immunosuppressive enzyme that catabolizes the essential amino acid, tryptophan (Trp), into the metabolite, kynurenine. IDO is expressed in >90% of patient resected GBM. IDO suppresses the anti-br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::494c6654c08b58f5be6b4ffa1996425d
https://doi.org/10.1093/neuonc/noac209.108
https://doi.org/10.1093/neuonc/noac209.108
Autor:
Lijie Zhai, April Bell, Kristen Lauing, Prashant Bommi, Erik Ladomersky, Xinlei Mi, Masha Kocherginski, James Chandler, Craig Horbinski, Amy Heimberger, Rimas Lukas, Derek Wainwright
Publikováno v:
Neuro-Oncology. 24:vii132-vii132
OBJECTIVE Previous work indicates poorer survival outcomes for older glioblastoma (GBM) patients ≥ 65 years of age as compared to younger patients < 65 years of age. The cellular mechanisms associated with this age-dependent survival difference rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9599fadba3009709f2c2e2ea2a25a807
https://doi.org/10.1093/neuonc/noac209.504
https://doi.org/10.1093/neuonc/noac209.504
Autor:
Teresa Nguyen, Dong Ho Shin, Debora Kim, Sanjay K Singh, Hong Jiang, Xuejun Fan, Yanhua Yi, Joy Gumin, Frederick Lang, Christopher Alvarez-Breckenridge, Marta M Alonso, Lijie Zhai, Erik Ladomersky, Kristen Lauing, Derek Wainwright, Juan Fueyo, Candelaria Gomez-Manzano
Publikováno v:
Neuro-Oncology. 24:vii223-vii223
Oncolytic viruses are considered part of immunotherapy and have shown promise in preclinical experiments and clinical trials in a small fraction of patients. To improve the response rate, it is necessary to reshape the tumor microenvironment that shi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bde63d50ba3c75e461855ed156d72eef
https://doi.org/10.1093/neuonc/noac209.860
https://doi.org/10.1093/neuonc/noac209.860
Autor:
Erik Rabin, Xinlei Mi, Jonathan Huang, Miri Kim, Andreas Mozny, Christina Amidei, Erica Sieg, April Bell, Lijie Zhai, Prashant Bommi, Kristen Lauing, Rimas Lukas, Derek Wainwright
Publikováno v:
Neuro-Oncology. 24:vii111-vii111
Glioblastoma is the most common primary malignant brain tumor in adults. Age is a prognostic factor for grade IV glioma (GIV) survival, where older adults 65 and older, tend to have quicker mortality compared to adults 18-64. This may be due to intri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::841c683e24b8383f3e6faa6645df51d8
https://doi.org/10.1093/neuonc/noac209.418
https://doi.org/10.1093/neuonc/noac209.418
Autor:
Erik Rabin, Xinlei Mi, Jonathan Huang, Miri Kim, Andreas Mozny, Christina Amidei, Erica Sieg, April Bell, Lijie Zhai, Prashant Bommi, Kristen Lauing, Rimas Lukas, Derek Wainwright
Publikováno v:
Neuro-Oncology. 24:vii111-vii111
Glioblastomas are the most common primary malignant brain tumor in adults. Subject age is a strong prognostic factor for survival. We performed a co-morbidity analysis of younger vs. older (greater than 65 years) adults with grade IV gliomas (GIV) to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfcf083399f1e983d54bf90a939c4fe7
https://doi.org/10.1093/neuonc/noac209.419
https://doi.org/10.1093/neuonc/noac209.419
Autor:
Ari J. Rosenberg, Derek A. Wainwright, Angela J. Fought, Lijie Zhai, Kristen Lauing, Victoria M. Villaflor
Publikováno v:
Cancer Research. 79:2341-2341
Background: Immune checkpoint blockade is emerging as an important immunotherapeutic strategy in esophageal cancer, yet response rates remain low. IDO1 is a rate-limiting immunosuppressive enzyme that may contribute to resistance to immune checkpoint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f552bb4a2e9077ef58f8bebb4d7246ea
https://doi.org/10.1158/1538-7445.am2019-2341
https://doi.org/10.1158/1538-7445.am2019-2341