Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kristen L. Howell"'
Publikováno v:
eLife, Vol 9 (2020)
Tendon injuries are common with poor healing potential. The paucity of therapies for tendon injuries is due to our limited understanding of the cells and molecular pathways that drive tendon regeneration. Using a mouse model of neonatal tendon regene
Externí odkaz:
https://doaj.org/article/2216a7d8a53b429b820e168b94096396
Autor:
Kristen L. Howell, Matthias A. Zumstein, Helen L. Moser, Adam C. Abraham, Alice H. Huang, Leesa M. Galatz, Damien M. Laudier
Publikováno v:
J Orthop Res
Rotator cuff supraspinatus tendon injuries are common with high rates of anatomic failure after surgical repair. The purpose of the study was to define clinically relevant features of a mouse model of supraspinatus tendon injury to determine painful,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0568e98e6088fe49a35044d8feed4ee7
https://doi.org/10.1002/jor.24769
https://doi.org/10.1002/jor.24769
Tendinopathy is a common clinical problem leading to significant musculoskeletal disability. Using a neonatal mouse model of tendon regeneration compared to adult tendon fibrosis, we identified a unique immune profile in regeneration that is associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edabf7a771e1c2883ae3711b343bb60d
https://doi.org/10.1101/2021.05.12.443424
https://doi.org/10.1101/2021.05.12.443424
Autor:
Alice H. Huang, Angela Montero, Deepak Kaji, Kristen L. Howell, Kenji Yeoh, Thomas M. Li, Philip Nasser
Publikováno v:
FASEB J
Tendons are dense connective tissues that transmit muscle forces to the skeleton. After adult injury, healing potential is generally poor and dominated by scar formation. Although the immune response is a key feature of healing, the specific immune c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfcf3cc230044cbdf17447b102b0c7ef
https://doi.org/10.1096/fj.202100049r
https://doi.org/10.1096/fj.202100049r
Tendons are dense connective tissues that transmit muscle forces to the skeleton. After adult injury, healing potential is generally poor and dominated by scar formation. Although the immune response is a key feature of healing, the specific immune c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::031183be43cf0dc1908d2bf2b46e8538
https://doi.org/10.1101/2021.01.07.425735
https://doi.org/10.1101/2021.01.07.425735
Tendon injuries are common with poor healing potential. The paucity of therapies for tendon is due to our limited understanding of the cells and molecules that drive tendon regeneration. Using a model of neonatal mouse tendon regeneration, we determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b2feb7337e892933ac9b8041630d52
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Tendon injuries are common with poor healing potential. The paucity of therapies for tendon injuries is due to our limited understanding of the cells and molecular pathways that drive tendon regeneration. Using a mouse model of neonatal tendon regene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34cc72d078243f8db1a1f62f30a4f70
https://pubmed.ncbi.nlm.nih.gov/32501213
https://pubmed.ncbi.nlm.nih.gov/32501213
Autor:
Kristen L. Howell, Douglas R. Keene, Sara F. Tufa, Alice H. Huang, Nelly Andarawis-Puri, Damien M. Laudier, Rebecca Bell, Chun Chien
Publikováno v:
Scientific Reports
To date, the cell and molecular mechanisms regulating tendon healing are poorly understood. Here, we establish a novel model of tendon regeneration using neonatal mice and show that neonates heal via formation of a ‘neo-tendon’ that differentiate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd2e726e68e6688b7ced0a4994f384fb