Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Kristen Kwong"'
Autor:
Jacqueline Morales, David V. Allegakoen, José A. Garcia, Kristen Kwong, Pushpendra K. Sahu, Drew A. Fajardo, Yue Pan, Max A. Horlbeck, Jonathan S. Weissman, W. Clay Gustafson, Trever G. Bivona, Amit J. Sabnis
Publikováno v:
JCI Insight, Vol 7, Iss 23 (2022)
Oncogenic FOXO1 gene fusions drive a subset of rhabdomyosarcoma (RMS) with poor survival; to date, these cancer drivers are therapeutically intractable. To identify new therapies for this disease, we undertook an isogenic CRISPR-interference screen t
Externí odkaz:
https://doaj.org/article/07f18a49460b42de8d0814e3d0166e10
Publikováno v:
Clinical Cancer Research. 28:A015-A015
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children. Although FOXO1 fusions portend a dismal prognosis for patients with both localized (5-year survival 65%) and metastatic (19%) disease, current therapy is largely agnostic to f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43978a0d9fbce62785d90c176788acff
https://doi.org/10.1158/1557-3265.sarcomas22-a015
https://doi.org/10.1158/1557-3265.sarcomas22-a015