Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Kristen Kasza"'
Autor:
Edwin M. Posadas, Walter M. Stadler, Elizabeth K. Chung, Kristen Kasza, Theodore Karrison, Olwen Hahn, Elizabeth Manchen
Publikováno v:
American Journal of Clinical Oncology. 34:150-154
Renal cancer accounts for approximately 58,000 (4%) of new noncutaneous cancer cases and is estimated to result in approximately 13,000 deaths in the United States in 2009.1 The introduction of mTOR and vascular endothelial growth factor (VEGF) pathw
Autor:
Masha Kocherginsky, Anna B. Halpern, Everett E. Vokes, Kristen Kasza, R. Williams, Ezra E.W. Cohen
Publikováno v:
Oral Oncology. 45:e155-e160
Single agent epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) have demonstrated reproducible response rates of 5-15% in treatment of squamous cell carcinomas of the head and neck (SCCHN). The subset of patients that benefits m
Autor:
Hedy L. Kindler, Everett E. Vokes, Rafat Ansari, David A. Taber, Halla Sayed Nimeiri, Kristen Kasza, D. A. Singh
Publikováno v:
Investigational New Drugs. 28:854-858
Purpose Hepatobiliary cancers respond poorly to cytotoxic chemotherapy. We evaluated the activity and safety of ixabepilone, an epothilone B analogue which stabilizes microtubules, in a phase II trial in patients with advanced cancers of the gallblad
Publikováno v:
Cancer Prevention Research. 2:385-393
Despite numerous advances, the 5-year survival rate for head and neck squamous cell cancer (HNSCC) has remained largely unchanged. This poor outcome is due to several variables, including the development of multiple primary tumors. Therefore, it is e
Autor:
Vanja Dukic, Kate E. Pickett, Andrew D. Skol, Nancy J. Cox, Gretchen Biesecker, Emily O. Kistner, Daniel S. Pine, Kristen Kasza, James L. Burns, Rosalind J. Wright, Edwin H. Cook, Robert James Blair, Lauren S. Wakschlag, Bennett L. Leventhal
Publikováno v:
Molecular psychiatry
Genetic susceptibility to antisocial behavior may increase fetal sensitivity to prenatal exposure to cigarette smoke. Testing putative gene x exposure mechanisms requires precise measurement of exposure and outcomes. We tested whether a functional po
Autor:
Carrie W. Rinker-Schaeffer, Walter M. Stadler, Kenneth J. Pienta, Javed Siddiqui, Ramasamy Jagadeeswaran, Hikmat Al-Ahmadie, Ravi Salgia, Edwin M. Posadas, Victoria L. Robinson, Kristen Otto, Kristen Kasza, Maria Tretiakov
Publikováno v:
BJU International. 103:171-177
OBJECTIVE To test the hypothesis that FYN, a member of the SRC family of kinases (SFKs), is up-regulated in prostate cancer, as FYN is functionally distinct from other SFKs, and interacts with FAK and paxillin (PXN), regulators of cell morphology and
Publikováno v:
Human Genomics
Human Genomics, Vol 3, Iss 2, Pp 128-142 (2009)
Human Genomics, Vol 3, Iss 2, Pp 128-142 (2009)
Carboplatin is a chemotherapeutic agent used in the management of many cancers, yet treatment is limited by resistance and toxicities. To achieve a better understanding of the genetic contribution to carboplatin resistance or toxicities, lymphoblasto
Autor:
Kristen Kasza, Catherine M. Bartnik, Edward B. Maryon, Cara A. Rabik, John T. Shafer, M. Eileen Dolan
Publikováno v:
Cancer Chemotherapy and Pharmacology. 64:133-142
Copper transporters have been proposed to be involved in cellular import and export of platinating agents. Expression of the human copper transporter 1 (hCtr1) is thought to result in increased sensitivity to cisplatin, whereas expression of ATP7A an
Autor:
Sharon Trevino, Qing Ma, Elaine M. Worcester, Michael O'Connor, Michael R. Bennett, Kristen Kasza, David J. Konczal, Patrick T. Murray, Jai Raman, Valluvan Jeevanandam, Jay L. Koyner, Prasad Devarajan
Publikováno v:
Kidney International. 74:1059-1069
There is a need to develop early biomarkers of acute kidney injury following cardiac surgery, where morbidity and mortality are increased by its presence. Plasma cystatin C (CyC) and plasma and urine Neutrophil Gelatinase Associated Lipocalin (NGAL)
Publikováno v:
Obstetrics & Gynecology. 111:256-266
OBJECTIVE: To identify predictors of comprehensive sex education in public schools. METHODS: Using a three-stage design, 335 sex education teachers from a probability sample of 201 schools in 112 Illinois school districts were surveyed regarding the