Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kristen K McCampbell"'
Autor:
Jeffrey Schlom, Claudia Palena, Kristen Fousek, Zhen Su, Duane H Hamilton, Hanne Lind, Lucas A Horn, Jeffrey Riskin, Heidi A Hempel, Kristen K McCampbell, Dean Y Maeda, John A Zebala
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Despite the success of immune checkpoint blockade therapy in the treatment of certain cancer types, only a small percentage of patients with solid malignancies achieve a durable response. Consequently, there is a need to develop novel appr
Externí odkaz:
https://doaj.org/article/13511483f12b409eb6e9c8522f26161d
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
The acquisition of mesenchymal features by carcinoma cells is now recognized as a driver of metastasis and tumor resistance to a range of anticancer therapeutics, including chemotherapy, radiation, and certain small-molecule targeted therapies. With
Externí odkaz:
https://doaj.org/article/fff7367ee457439dbb1c9d4081ea0849
Autor:
Justin M. David, Charli Dominguez, Kristen K. McCampbell, James L. Gulley, Jeffrey Schlom, Claudia Palena
Publikováno v:
OncoImmunology, Vol 6, Iss 10 (2017)
Mesenchymalization is a cellular and molecular program in which epithelial cells progressively lose their well-differentiated phenotype and adopt mesenchymal characteristics. Tumor mesenchymalization occurs during the progression of cancer to metasta
Externí odkaz:
https://doaj.org/article/b287c2419c3c4e3faffb2aa16be96e38
Publikováno v:
Stem Cells International, Vol 2015 (2015)
The zebrafish is a useful animal model to study the signaling pathways that orchestrate kidney regeneration, as its renal nephrons are simple, yet they maintain the biological complexity inherent to that of higher vertebrate organisms including mamma
Externí odkaz:
https://doaj.org/article/ec17dcac56164fb5878efd2b67680cca
Autor:
Kristen Fousek, John A. Zebala, Heidi Hempel, Dean Y. Maeda, Duane H. Hamilton, Claudia Palena, Hanne Lind, Jeffrey Schlom, Zhen Su, Lucas A. Horn, Jeffrey Riskin, Kristen K. McCampbell
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundDespite the success of immune checkpoint blockade therapy in the treatment of certain cancer types, only a small percentage of patients with solid malignancies achieve a durable response. Consequently, there is a need to develop novel appro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db0c43e3d6cb49514f368e5509c7d49
https://jitc.bmj.com/content/8/1/e000326.full
https://jitc.bmj.com/content/8/1/e000326.full
Autor:
Wolfram Goessling, Rebecca A. Wingert, Ryan Thummel, Michael McKernan, Annemarie Fox, Gary F. Gerlach, Amanda N. Marra, Bridgette E. Drummond, Kristen K. McCampbell, Adriana Rodríguez-Marí, Paul T. Kroeger, Ignaty Leshchiner, Ruth Bremiller, John H. Postlethwait, Alan J. Davidson, Rachel Miceli
Publikováno v:
Developmental Biology. 428:148-163
The zebrafish kidney is conserved with other vertebrates, making it an excellent genetic model to study renal development. The kidney collects metabolic waste using a blood filter with specialized epithelial cells known as podocytes. Podocyte formati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6621260b3f97eee269081749f3235a
https://doi.org/10.1016/j.ydbio.2017.05.025
https://doi.org/10.1016/j.ydbio.2017.05.025
Autor:
Lucas A. Horn, Heidi Hempel, Jeffrey Schlom, Kristen Fousek, Claudia Palena, Kristen K. McCampbell, Jeffrey Riskin, Duane H. Hamilton, Hanne Lind
Publikováno v:
Cancer Immunology Research. 8:B43-B43
The occurrence of phenotypic plasticity in carcinomas, which results in the acquisition of mesenchymal features by epithelial cancer cells, associates with a poor prognosis and has been described as a mechanism of primary resistance and failure to tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7012585c818d6177e1eca6e14c12c605
https://doi.org/10.1158/2326-6074.tumimm19-b43
https://doi.org/10.1158/2326-6074.tumimm19-b43
Publikováno v:
JCI Insight. 2
The complex signaling networks of the tumor microenvironment that facilitate tumor growth and progression toward metastatic disease are becoming a focus of potential therapeutic options. The chemokine IL-8 is overexpressed in multiple cancer types, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca022a6722d475b505f7fe21b45e09f2
https://doi.org/10.1172/jci.insight.94296
https://doi.org/10.1172/jci.insight.94296
Autor:
Amber J. Giles, Deric M. Park, Claudia Palena, Ashlee Seldomridge, Kristan Meetze, Heather Sonnemann, Kristen K. McCampbell, Mark R. Gilbert, Jinkyu Jung, Orieta Celiku
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940d35f628138cd1049c13f7cdbf20b8
https://europepmc.org/articles/PMC5692901/
https://europepmc.org/articles/PMC5692901/
Autor:
Claudia Palena, James L. Gulley, Jeffrey Schlom, Kristen K. McCampbell, Justin M. David, Charli Dominguez
Publikováno v:
OncoImmunology, Vol 6, Iss 10 (2017)
Oncoimmunology
Oncoimmunology
Mesenchymalization is a cellular and molecular program in which epithelial cells progressively lose their well-differentiated phenotype and adopt mesenchymal characteristics. Tumor mesenchymalization occurs during the progression of cancer to metasta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d185201ce5d82e0011c0e06b0cc434
https://doaj.org/article/b287c2419c3c4e3faffb2aa16be96e38
https://doaj.org/article/b287c2419c3c4e3faffb2aa16be96e38