Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kristen K B Barthel"'
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118229 (2015)
microRNAs (miRNAs) are short non-coding RNAs that can mediate changes in gene expression and are required for the formation of skeletal muscle (myogenesis). With the goal of identifying novel miRNA biomarkers of muscle disease, we profiled miRNA expr
Externí odkaz:
https://doaj.org/article/af2c31cdb09245da92c657f63e6b90ba
Autor:
Kristen K B Barthel, Xuedong Liu
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2184 (2008)
The revelation that the human genome encodes only approximately 25,000 genes and thus cannot account for phenotypic complexity has been one of the biggest surprises in the post-genomic era. However, accumulating evidence suggests that transcriptional
Externí odkaz:
https://doaj.org/article/bec5d367c8d24704a995f20ae47dceee
Myoblast replication is reduced in the IUGR fetus despite maintained proliferative capacity in vitro
Autor:
Susan M Soto, Bifeng Gao, Leslie A. Leinwand, Paul J. Rozance, Amy C Blake, Jacob E. Friedman, Carrie E. McCurdy, Natalia G Garza, Stephanie R. Wesolowski, Byron Hetrick, William W. Hay, Laura D. Brown, Kristen K. B. Barthel
Publikováno v:
Journal of Endocrinology. 232:475-491
Adults who were affected by intrauterine growth restriction (IUGR) suffer from reductions in muscle mass and insulin resistance, suggesting muscle growth may be restricted by molecular events that occur during fetal development. To explore the basis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351891ff9589967a49ef3f362ca1a6e6
https://doi.org/10.1530/joe-16-0123
https://doi.org/10.1530/joe-16-0123
Publikováno v:
Journal of Molecular Biology. 426:1766-1785
In a widely accepted model, the steroid receptor RNA activator protein (SRA protein; SRAP) modulates the transcriptional regulatory activity of SRA RNA by binding a specific stem–loop of SRA. We first confirmed that SRAP is present in the nucleus a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03df6a8dd371be0dda45ad2f1e385352
https://doi.org/10.1016/j.jmb.2014.01.006
https://doi.org/10.1016/j.jmb.2014.01.006
Autor:
Pamela A. Harvey, Elizabeth D. Luczak, Leslie A. Leinwand, Peter A. Watson, John P. Konhilas, Kristen K. B. Barthel, Christopher D. Haines, Brian L. Stauffer
Publikováno v:
Endocrinology. 153:4470-4479
Hypertrophic cardiomyopathy (HCM) is more severe in male than female mice eating a soy-based diet. We sought to determine whether the detrimental effects are mediated by the phytoestrogens present in soy, the mechanism by which phytoestrogens act, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c033399b376280f58fae85b51c15a5a
https://doi.org/10.1210/en.2012-1391
https://doi.org/10.1210/en.2012-1391
Autor:
Elizabeth D. Luczak, Tom H. Cheung, John P. Konhilas, Brian L. Stauffer, Kristen K. B. Barthel, Leslie A. Leinwand
Publikováno v:
Physiological Genomics. 43:772-780
The perception that soy food products and dietary supplements will have beneficial effects on cardiovascular health has led to a massive consumer market. However, we have previously noted that diet profoundly affects disease progression in a genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b910b83a6056738f1bb1c8ed6083ee
https://doi.org/10.1152/physiolgenomics.00237.2010
https://doi.org/10.1152/physiolgenomics.00237.2010
Autor:
Kristen K. B. Barthel, Reza Kalhor, James C. Stroud, Lin Chen, Michael J. Giffin, Darren L. Bates, Yongqing Wu
Publikováno v:
Structure. 16:684-694
The host factor, nuclear factor of activated T-cells (NFAT), regulates the transcription and replication of HIV-1. Here, we have determined the crystal structure of the DNA binding domain of NFAT bound to the HIV-1 long terminal repeat (LTR) tandem k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d73261b6b4e9fa2fc0f5787a2aa809
https://doi.org/10.1016/j.str.2008.01.020
https://doi.org/10.1016/j.str.2008.01.020
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118229 (2015)
PLoS ONE
PLoS ONE
microRNAs (miRNAs) are short non-coding RNAs that can mediate changes in gene expression and are required for the formation of skeletal muscle (myogenesis). With the goal of identifying novel miRNA biomarkers of muscle disease, we profiled miRNA expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b980a4c436dfc1297fada3876a4a1f
http://europepmc.org/articles/PMC4331529?pdf=render
http://europepmc.org/articles/PMC4331529?pdf=render
Publikováno v:
Experimental Cell Research. 312:2132-2141
Myogenic differentiation is a fundamental biological process that involves a hierarchical series of events that ultimately leads to muscle-specific gene expression and myofiber formation. Posttranslational modifications of the myogenic regulatory fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1888bf4f6e27833ce5458889e26615
https://doi.org/10.1016/j.yexcr.2006.03.016
https://doi.org/10.1016/j.yexcr.2006.03.016
Publikováno v:
Journal of Cellular and Molecular Medicine
Myocyte enhancer factor 2 (MEF2) transcription factors are crucial regulators controlling muscle-specific and growth factor-inducible genes. Numerous studies have reported that the activity of these transcription factors is tightly modulated by postt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2b4f0fa7423341d4c7a11cac2b62fb
https://doi.org/10.1111/j.1582-4934.2006.tb00295.x
https://doi.org/10.1111/j.1582-4934.2006.tb00295.x