Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kristen J. Wade"'
Autor:
Kristen J. Wade, Rayo Suseno, Kerry Kizer, Jacqueline Williams, Juliano Boquett, Stacy Caillier, Nicholas R. Pollock, Adam Renschen, Adam Santaniello, Jorge R. Oksenberg, Paul J. Norman, Danillo G. Augusto, Jill A. Hollenbach
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-23 (2024)
Abstract The extremely high levels of genetic polymorphism within the human major histocompatibility complex (MHC) limit the usefulness of reference-based alignment methods for sequence assembly. We incorporate a short-read, de novo assembly algorith
Externí odkaz:
https://doaj.org/article/da420c82ac434ddc86e06bc9431d32c9
Autor:
Kristen J. Wade, Samantha Tisa, Chloe Barrington, Jesslyn C. Henriksen, Kristy R. Crooks, Christopher R. Gignoux, Austin T. Almand, J. Jordan Steel, John C. Sitko, Joseph W. Rohrer, Douglas P. Wickert, Erin A. Almand, David D. Pollock, Olivia S. Rissland
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Since the initial reported discovery of SARS-CoV-2 in late 2019, genomic surveillance has been an important tool to understand its transmission and evolution. Here, we sought to describe the underlying regional phylodynamics before and during a rapid
Externí odkaz:
https://doaj.org/article/e6e4d5f387f44096bfa6f740e0ccc6f9
Autor:
Divya S. Vinjamur, Kristen J. Wade, Safa F. Mohamad, Jack L. Haar, Stephen T. Sawyer, Joyce A. Lloyd
Publikováno v:
Haematologica, Vol 99, Iss 10 (2014)
The Krüppel-like transcription factors KLF1 and KLF2 are essential for embryonic erythropoiesis. They can partially compensate for each other during mouse development, and coordinately regulate numerous erythroid genes, including the β-like globins
Externí odkaz:
https://doaj.org/article/e0656e8682134a0cac501bac088eda62
Autor:
Colin R. Zamecnik, Gavin M. Sowa, Ahmed Abdelhak, Ravi Dandekar, Rebecca D. Bair, Kristen J. Wade, Christopher M. Bartley, Asritha Tubati, Refujia Gomez, Camille Fouassier, Chloe Gerungan, Jessica Alexander, Anne E. Wapniarski, Rita P. Loudermilk, Erica L. Eggers, Kelsey C. Zorn, Kirtana Ananth, Nora Jabassini, Sabrina A. Mann, Nicholas R. Ragan, Adam Santaniello, Roland G. Henry, Sergio E. Baranzini, Scott S. Zamvil, Riley M. Bove, Chu-Yueh Guo, Jeffrey M. Gelfand, Richard Cuneo, H.-Christian von Büdingen, Jorge R. Oksenberg, Bruce AC Cree, Jill A. Hollenbach, Ari J. Green, Stephen L. Hauser, Mitchell T. Wallin, Joseph L. DeRisi, Michael R. Wilson
Publikováno v:
medRxiv
Although B cells are implicated in multiple sclerosis (MS) pathophysiology, a predictive or diagnostic autoantibody remains elusive. Here, the Department of Defense Serum Repository (DoDSR), a cohort of over 10 million individuals, was used to genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac96b2bbc77aa7d1a7a685cce7b501a
https://europepmc.org/articles/PMC10187343/
https://europepmc.org/articles/PMC10187343/
Autor:
Zachary L. Nikolakis, Richard H. Adams, Kristen J. Wade, Andrea J. Lund, Elizabeth J. Carlton, Todd A. Castoe, David D. Pollock
Publikováno v:
Frontiers in Epidemiology. 2
Schistosomiasis is a neglected tropical disease caused by multiple parasitic Schistosoma species, and which impacts over 200 million people globally, mainly in low- and middle-income countries. Genomic surveillance to detect evidence for natural sele
Autor:
Andrea J. Lund, Kristen J. Wade, Zachary L. Nikolakis, Kathleen Ivey, Blair W. Perry, Hamish Pike, Sara H. Paull, Yang Liu, Todd A. Castoe, David D. Pollock, Elizabeth J. Carlton
The global community has adopted ambitious goals to eliminate schistosomiasis as a public health problem, and new tools are needed to achieve them. Mass drug administration programs, for example, have reduced the burden of schistosomiasis, but the id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::177773e29176ef5c50b996d296646f75
https://doi.org/10.31219/osf.io/rt8wn
https://doi.org/10.31219/osf.io/rt8wn
Integrating genomic and epidemiologic data to accelerate progress toward schistosomiasis elimination
Autor:
Andrea J, Lund, Kristen J, Wade, Zachary L, Nikolakis, Kathleen N, Ivey, Blair W, Perry, Hamish N C, Pike, Sara H, Paull, Yang, Liu, Todd A, Castoe, David D, Pollock, Elizabeth J, Carlton
Publikováno v:
eLife. 11
The global community has adopted ambitious goals to eliminate schistosomiasis as a public health problem, and new tools are needed to achieve them. Mass drug administration programs, for example, have reduced the burden of schistosomiasis, but the id
Publikováno v:
Mathematical Biosciences and Engineering, Vol 17, Iss 1, Pp 122-143 (2020)
Mathematical biosciences and engineering : MBE
Mathematical biosciences and engineering : MBE
Expression quantitative trait loci (eQTL) analyses detect genetic variants (SNPs) associated with RNA expression levels of genes. The conventional eQTL analysis is to perform individual tests for each gene-SNP pair using simple linear regression and
Autor:
Joseph W. Rohrer, J. Jordan Steele, David D. Pollock, Kristen J. Wade, Austin T. Almand, John C Sitko, Chloe Barrington, Christopher R. Gignoux, Erin A. Almand, Kristy Crooks, Olivia S. Rissland, Douglas P. Wickert, Samantha Tisa
Since the initial reported discovery of SARS-CoV-2 in late 2019, genomic surveillance has been an important tool to understand its transmission and evolution. Here, we describe a case study of genomic sequencing of Colorado SARS-CoV-2 samples collect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a52d1260501769940cd3b168b5fc2c6e
https://doi.org/10.1101/2021.09.28.21262976
https://doi.org/10.1101/2021.09.28.21262976
The increasingly widespread availability of genomic data has created a growing need for fast, sensitive and scalable comparative analysis methods. A key aspect of comparative genomic analysis is the study of synteny, co-localized gene clusters shared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ec7b10741bbe90cb7043746214009bf
https://doi.org/10.1101/2021.06.03.446950
https://doi.org/10.1101/2021.06.03.446950