Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kristen Gambles"'
Autor:
K. Sree Kumar, Lynnette H. Cary, Kristen Gambles, Martin Hauer-Jensen, Sanchita P. Ghosh, Shilpa Kulkarni
Publikováno v:
International Immunopharmacology. 14:495-503
Gamma-tocotrienol (GT3), a promising radioprotectant, is shown to protect CD2F1 mice from radiation-induced neutropenia and thrombocytopenia when given 24h prior to total-body irradiation. GT3 also is shown to increase white blood cells (WBC) and abs
Autor:
Kristen Gambles, Michael W Perkins, Thomas M. Seed, Tzu-Cheg Kao, K. S. Kumar, Kevin P. Hieber, Roli L Pessu, Sanchita P. Ghosh, Manoj Maniar, Shilpa Kulkarni
Publikováno v:
Journal of radiation research
The aim of the present study was to assess recovery from hematopoietic and gastrointestinal damage by Ex-RAD , also known as ON01210.Na (4-carboxystyryl-4-chlorobenzylsulfone, sodium salt), after total body radiation. In our previous study, we report
Autor:
Martin Hauer-Jensen, Steven R. Mog, Shilpa Kulkarni, Merriline M. Satyamitra, Raymond Toles, Kevin P. Hieber, Tzu Cheg Kao, Sanchita P. Ghosh, Lyudmila Romanyukha, K. Sree Kumar, Kristen Gambles
Publikováno v:
Radiation Research. 173:738-747
We analyzed the radioprotective effects of gamma-tocotrienol (GT3) on hematopoietic stem cells (HSCs) and progenitor cells (HPCs) in sublethally irradiated mice. Flow cytometry analysis indicated that radiation depleted HPCs (c-Kit(+), Lin(-)) to 40%