Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kristen Fread"'
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-7 (2024)
Abstract Single-cell methods offer a high-resolution approach for characterizing cell populations. Many studies rely on single-cell transcriptomics to draw conclusions regarding cell state and behavior, with the underlying assumption that transcripto
Externí odkaz:
https://doaj.org/article/033eded111be43eba9ede3b25365e639
Autor:
Logan F. McColl, Xizhao Chen, Michael D. Solga, Kailo Schlegel, Sean P. Haughey, Peter I. Lobo, Kristen Fread, Eli Zunder, Ryan Cha, Stephen Park, J. Jared Christophel, Quanjun Cui, Abhijit S. Dighe
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionBone morphogenetic proteins (BMPs) are used as key therapeutic agents for the treatment of difficult fractures. While their effects on osteoprogenitors are known, little is known about their effects on the immune system.MethodsWe used per
Externí odkaz:
https://doaj.org/article/6a95833bf15047f581910d926ff31bc1
Autor:
Xiaolin Zhao, Carla V. Finkielstein, Jeffrey Ellena, Mary K. Brannon, Kristen Fread, Wen Xiong, Daniel G. S. Capelluto, John H. Bushweller, Shuyan Xiao, Geoffrey Armstrong
Publikováno v:
Biophysical Journal. 110(3)
Early endosomes represent the first sorting station for vesicular ubiquitylated cargo. Cargo transport is mediated by the endosomal sorting complex required for transport (ESCRT) machinery. Similar to the structural organization of ESCRT-0 proteins,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08c5666c6b46957c1a8268988e943a0
Autor:
Jeffrey F. Ellena, Shuyan Xiao, Daniel G. S. Capelluto, John H. Bushweller, Geoffrey S. Armstrong, Carla V. Finkielstein, Mary K. Brannon, Kristen Fread
Publikováno v:
Biophysical Journal. 108:343a
Many cellular signaling processes require internalization of ubiquitylated cargo via endocytosis and early endosomes are the first sorting station for vesicular cargo. Adaptor protein complexes modulate signaling output in early endosomes by triggeri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbacee3cf55dd4b0fa3dbdbb63244218
https://doi.org/10.1016/j.bpj.2014.11.1880
https://doi.org/10.1016/j.bpj.2014.11.1880
Autor:
Mary K. Brannon, Shuyan Xiao, Geoffrey S. Armstrong, Kristen Fread, Daniel G. S. Capelluto, Carla V. Finkielstein
Publikováno v:
Biophysical Journal. 106:661a
Adaptor proteins are often committed to cellular processes that involve cargo internalization from the plasma membrane. Ubiquitinated cargo is internalized by endocytosis and delivered to early endosomes via intracellular vesicles. Cargo is then sort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8551747382e331e0e4643c5dd8ca71c
https://doi.org/10.1016/j.bpj.2013.11.3661
https://doi.org/10.1016/j.bpj.2013.11.3661