Výsledky vyhledávání - "Kristen Focht"

Phase III, efficacy and safety study of ertugliflozin monotherapy in people with type 2 diabetes mellitus inadequately controlled with diet and exercise alone

Autor: Gregory T. Golm, Kristen Focht, Steven G. Terra, Brett Lauring, Didier Saur, Jeremy Johnson, Samuel Dagogo-Jack, Melanie J. Davies, Giuseppe Derosa, Juan P. Frias, Amanda Darekar

Publikováno v: Diabetes, Obesity and Metabolism. 19:721-728

Aims To conduct a phase III study to evaluate the efficacy and safety of ertugliflozin monotherapy in people with type 2 diabetes. Materials and methods This was a 52-week, double-blind, multicentre, randomized, parallel-group study with a 26-week, p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8640dc844a311f5e78eaf9f243c887
https://doi.org/10.1111/dom.12888

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Desvenlafaxine 50 and 100 mg/d Versus Placebo for the Treatment of Major Depressive Disorder

Autor: Michael E. Thase, Karen A. Tourian, Eunhee Hwang, Anita H. Clayton, Kristen Focht, Ru-fong J. Cheng

Publikováno v: The Journal of Clinical Psychiatry. 76:562-569

To assess short-term efficacy and safety of desvenlafaxine 50 and 100 mg/d versus placebo for treating major depressive disorder (MDD). Assessment of sexual function was a secondary objective.Outpatients (≥ 18 years) who met criteria for MDD from t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0da98a38b1c1f55cbe342da334ef3ab
https://doi.org/10.4088/jcp.13m08978

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Cytochrome P450 2D6 Phenoconversion Is Common in Patients Being Treated for Depression

Autor: Kasia Lobello, Rana Fayyad, Kristen Focht, Gina Buckley, Cecelia P. Kane, Sheldon H. Preskorn, Christine J. Guico-Pabia, Alice I. Nichols

Publikováno v: The Journal of Clinical Psychiatry. 74:614-621

OBJECTIVE Determine the point prevalence of phenoconversion to cytochrome P450 2D6 (CYP2D6) poor metabolizer status in clinical practice. METHOD This multicenter, open-label, single-visit naturalistic study was conducted from October 2008 to July 200

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52406fbca872c7d679755580f6952bbf
https://doi.org/10.4088/jcp.12m07807

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An Evaluation of Sexual Functioning in Employed Outpatients with Major Depressive Disorder Treated with Desvenlafaxine 50mg or Placebo

Autor: Sujana Reddy, Rana Fayyad, Kristen Focht, Jeff Musgnung, Anita H. Clayton

Publikováno v: The Journal of Sexual Medicine. 10:768-776

Introduction. The symptoms of major depressive disorder (MDD) include sexual dysfunction, but antidepressant pharmacotherapies are also associated with treatment-emergent sexual dysfunction. Aim. These secondary and post hoc analyses evaluated sexual

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b865e71f183f9be3290982f301c84009
https://doi.org/10.1111/j.1743-6109.2012.02899.x

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Efficacy and safety of desvenlafaxine 50 mg/d in a randomized, placebo-controlled study of perimenopausal and postmenopausal women with major depressive disorder

Autor: Jeff Musgnung, Anita H. Clayton, Philip T. Ninan, Susan G. Kornstein, Tanya Ramey, Boadie W. Dunlop, Weihang Bao, Kristen Focht

Publikováno v: The Journal of clinical psychiatry. 74(10)

OBJECTIVE Evaluate the 8-week efficacy and safety of desvenlafaxine at the recommended dose of 50 mg/d in perimenopausal and postmenopausal women with major depressive disorder (MDD) based on the Diagnostic and Statistical Manual of Mental Disorders,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49f2497c57bb792883108c8694b680d
https://pubmed.ncbi.nlm.nih.gov/24229754

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Symptomatic and functional improvement in employed depressed patients: a double-blind clinical trial of desvenlafaxine versus placebo

Autor: Boadie W. Dunlop, Christine J. Guico-Pabia, Sujana Reddy, Shannon Lubaczewski, Lingfeng Yang, Kristen Focht

Publikováno v: Journal of clinical psychopharmacology. 31(5)

This is the first study to assess the efficacy of desvenlafaxine (administered as desvenlafaxine succinate) for improving depressive symptoms and functioning exclusively in employed patients with major depressive disorder (MDD).Gainfully employed (�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f6bb1258397d3e7f549c05e1c01837
https://pubmed.ncbi.nlm.nih.gov/21869698

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Open-label treatment with desvenlafaxine in postmenopausal women with major depressive disorder not responding to acute treatment with desvenlafaxine or escitalopram

Autor: Qin Jiang, Susan G. Kornstein, Michael E. Thase, Claudio N. Soares, Christine J. Guico-Pabia, Anita H. Clayton, Phillip T. Ninan, Cecelia P. Kane, Kristen Focht

Publikováno v: CNS drugs. 25(3)

Preliminary clinical evidence indicates that menopausal status might impact on the efficacy of certain classes of antidepressants.The aim of this study was to evaluate open-label desvenlafaxine treatment (administered as desvenlafaxine succinate) in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23346ac81cb7f0250deb8ae211a51ef8
https://pubmed.ncbi.nlm.nih.gov/21323394

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Desvenlafaxine and escitalopram for the treatment of postmenopausal women with major depressive disorder

Autor: Kristen Focht, Cecelia P. Kane, Lee S. Cohen, Claudio N. Soares, Michael E. Thase, Phil Ninan, Susan G. Kornstein, Qin Jiang, Christine J. Guico-Pabia, Anita H. Clayton

Publikováno v: Menopause (New York, N.Y.). 17(4)

Objective: This study assessed the efficacy, safety, and tolerability of the serotonin-norepinephrine reuptake inhibitor desvenlafaxine and the selective serotonin reuptake inhibitor escitalopram for major depressive disorder (MDD) in postmenopausal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dced5554c3dfc2934f9635c4a15cf666
https://pubmed.ncbi.nlm.nih.gov/20505543

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