Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Kristen F. Gorman"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Adolescent idiopathic scoliosis (AIS) is the most prevalent pediatric spinal deformity. We previously demonstrated elongated cilia and an altered molecular mechanosensory response in AIS osteoblasts. The purpose of this exploratory study was
Externí odkaz:
https://doaj.org/article/04ffef3c95614e11b3ee224b633b251a
Autor:
Kristen F. Gorman, Giuseppe Banfi, Marie Yvonne Akoume, Maxime Veillette, Dina Nada, Hubert Labelle, Alessandra Colombini, Alain Moreau, Jean Ouellet, Mohamed Elbakry, Anita Franco, Charles H. Rivard, Giovanni Lombardi, Marco Brayda-Bruno, Guy Grimard, Stefan Parent, Jean-Marc Mac-Thiong
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports
Scientific Reports
Adolescent idiopathic scoliosis is the most prevalent spine deformity and the molecular mechanisms underlying its pathophysiology remain poorly understood. We have previously found a differential impairment of melatonin receptor signaling in AIS oste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ee4a281305dde72a49406386a7a990
http://link.springer.com/article/10.1038/s41598-019-46325-2
http://link.springer.com/article/10.1038/s41598-019-46325-2
Publikováno v:
Scientific Reports
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Adolescent idiopathic scoliosis (AIS) is the most prevalent pediatric spinal deformity. We previously demonstrated elongated cilia and an altered molecular mechanosensory response in AIS osteoblasts. The purpose of this exploratory study was to chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38fe4220bfb324c2460e161451a96759
https://pubmed.ncbi.nlm.nih.gov/35115632
https://pubmed.ncbi.nlm.nih.gov/35115632
Publikováno v:
PLoS ONE, Vol 1, p e76 (2006)
Hsp90 controls dramatic phenotypic transitions in a wide array of morphological features of many organisms. The genetic-background dependence of specific abnormalities and their response to laboratory selection suggested Hsp90 could be an 'evolutiona
Externí odkaz:
https://doaj.org/article/cf706bd7d64b4280a9ddaed33c09f4f8
Publikováno v:
Personalized medicine. 10(1)
Adolescent idiopathic scoliosis (AIS) is one of the most common childhood deformities worldwide, characterized by a 3D spinal deformity with unknown cause, and represents both an immediate medical challenge and a chronic condition affecting individua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf17fbb83d77e2d1506431bc5f35c18
https://pubmed.ncbi.nlm.nih.gov/29783473
https://pubmed.ncbi.nlm.nih.gov/29783473
Autor:
Kristen F. Gorman, Dina Nada, Marie Yvonne Akoume, Alain Moreau, Dawei Li, Emile Levy, Cédric Julien, Jason Kost, Mark E. Samuels, Pierre H. Rompré
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
The cellular and molecular mechanisms underlying spinal deformity progression in adolescent idiopathic scoliosis (AIS) remain poorly understood. In this study, 804 French-Canadian patients and 278 age- and sex-matched controls were enrolled and genot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c97d73e7a8a9fbbf3e0e78c988b4a9d
https://pubmed.ncbi.nlm.nih.gov/30952886
https://pubmed.ncbi.nlm.nih.gov/30952886
Publikováno v:
Scientific Reports
The primary cilium is an outward projecting antenna-like organelle with an important role in bone mechanotransduction. The capacity to sense mechanical stimuli can affect important cellular and molecular aspects of bone tissue. Idiopathic scoliosis (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176c736866a84888e22d4b602f3324e6
https://doi.org/10.1038/srep44260
https://doi.org/10.1038/srep44260
Publikováno v:
European Spine Journal
Purpose Idiopathic scoliosis is a complex developmental syndrome defined by an abnormal structural curvature of the spine. High treatment costs, chronic pain/discomfort, and the need for monitoring at-risk individuals contribute to the global healthc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e1f438943d8d5ca1aa48a03f06f26b
https://doi.org/10.1007/s00586-012-2389-6
https://doi.org/10.1007/s00586-012-2389-6
Model teleosts for the study of idiopathic-type spinal curvatures: potential biomedical applications
Publikováno v:
Journal of Applied Ichthyology. 28:353-359
Summary Elucidation of the genetic basis for heritable spinal curvature would be highly beneficial to medicine. Heritable spinal curvature among otherwise healthy children (i.e. idiopathic-type) accounts for more than 80% of all human spinal curvatur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd150b0e7c726ba5af6006d22cf92b36
https://doi.org/10.1111/j.1439-0426.2012.01982.x
https://doi.org/10.1111/j.1439-0426.2012.01982.x
Autor:
M. Pellicelli, Kristen F. Gorman, J.-F. Lavoie, Alain Moreau, Cynthia Picard, M. Taheri, Patrick Lavigne, Anita Franco
Publikováno v:
Osteoarthritis and Cartilage. 25:S19-S20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb295e43a3e82ad9e306fbf0ce58455a
https://doi.org/10.1016/j.joca.2017.02.046
https://doi.org/10.1016/j.joca.2017.02.046