Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Kristen E. Boyle"'
Autor:
Zhila Semnani-Azad, Romy Gaillard, Alice E. Hughes, Kristen E. Boyle, Deirdre K. Tobias, ADA/EASD PMDI, Wei Perng
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-14 (2024)
Abstract Background The objective of this systematic review is to identify prognostic factors among women and their offspring affected by gestational diabetes mellitus (GDM), focusing on endpoints of cardiovascular disease (CVD) and type 2 diabetes (
Externí odkaz:
https://doaj.org/article/9f556ad8015a41bd976925532771ffc6
Autor:
Catherine M. Bulka, Todd M. Everson, Amber A. Burt, Carmen J. Marsit, Margaret R. Karagas, Kristen E. Boyle, Sierra Niemiec, Katerina Kechris, Elizabeth J. Davidson, Ivana V. Yang, Jason I. Feinberg, Heather E. Volk, Christine Ladd-Acosta, Carrie V. Breton, T. Michael O’Shea, Rebecca C. Fry
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
The placenta undergoes many changes throughout gestation to support the evolving needs of the foetus. There is also a growing appreciation that male and female foetuses develop differently in utero, with unique epigenetic changes in placental tissue.
Externí odkaz:
https://doaj.org/article/ac82bc0e677b4fe1971c034cf1d44fb9
Autor:
Ashley Y. Song, Catherine M. Bulka, Sierra S. Niemiec, Katerina Kechris, Kristen E. Boyle, Carmen J. Marsit, T. Michael O’Shea, Rebecca C. Fry, Kristen Lyall, M. Daniele Fallin, Heather E. Volk, Christine Ladd-Acosta
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
Background: ‘Epigenetic clocks’ have been developed to accurately predict chronologic gestational age and have been associated with child health outcomes in prior work. Methods: We meta-analysed results from four prospective U.S cohorts investiga
Externí odkaz:
https://doaj.org/article/9b63eea7be7344c1b85939aa2c1aa51c
Autor:
Melissa L. Erickson, Devin Dobias, Madeline Rose Keleher, Dana Dabelea, Bryan C. Bergman, Josiane L. Broussard, Kristen E. Boyle
Publikováno v:
Nutrients, Vol 16, Iss 1, p 52 (2023)
Background: Exposure to intrauterine obesity can disrupt clock gene rhythmicity in animal models. The aim of this pilot study was to determine if maternal obesity alters rhythmic expression of core clock in mesenchymal stem cells (MSCs) from umbilica
Externí odkaz:
https://doaj.org/article/1f88dc2175c8499ca0a228a751bf70ed
Autor:
Melissa L. Erickson, Zachary W. Patinkin, Allison M. Duensing, Dana Dabelea, Leanne M. Redman, Kristen E. Boyle
Publikováno v:
JCI Insight, Vol 6, Iss 13 (2021)
Exposure to maternal obesity may promote metabolic dysfunction in offspring. We used infant mesenchymal stem cells (MSCs) to experimentally examine cellular mechanisms of intergenerational health transmission. Our earlier reports show MSCs collected
Externí odkaz:
https://doaj.org/article/44d08466b60d49dd88b095e07523ea3b
Autor:
Kristen E. Boyle, Zachary W. Patinkin, Allison L.B. Shapiro, Carly Bader, Lauren Vanderlinden, Katerina Kechris, Rachel C. Janssen, Rebecca J. Ford, Brennan K. Smith, Gregory R. Steinberg, Elizabeth J. Davidson, Ivana V. Yang, Dana Dabelea, Jacob E. Friedman
Publikováno v:
Molecular Metabolism, Vol 6, Iss 11, Pp 1503-1516 (2017)
Objective: Infants born to mothers with obesity have greater adiposity, ectopic fat storage, and are at increased risk for childhood obesity and metabolic disease compared with infants of normal weight mothers, though the cellular mechanisms mediatin
Externí odkaz:
https://doaj.org/article/c956e384a84b44429f534a27385f457e
Autor:
Kristen E. Boyle, Margaret J. Magill-Collins, Sean A. Newsom, Rachel C. Janssen, Jacob E. Friedman
Publikováno v:
Nutrients, Vol 12, Iss 3, p 767 (2020)
Overweight and obesity accompanies up to 70% of pregnancies and is a strong risk factor for offspring metabolic disease. Maternal obesity-associated inflammation and lipid profile are hypothesized as important contributors to excess offspring liver a
Externí odkaz:
https://doaj.org/article/6e0dcbd1386a439e9407365a3043f446
Autor:
Kimberley D. Bruce, Sachi Gorkhali, Katherine Given, Alison M. Coates, Kristen E. Boyle, Wendy B. Macklin, Robert H. Eckel
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Severe demyelinating disorders of the central nervous system (CNS) such as multiple sclerosis (MS), can be devastating for many young lives. To date, the factors resulting in poor remyelination and repair are not well understood, and reparative thera
Externí odkaz:
https://doaj.org/article/587e108b121c460f932699745d1afee4
Autor:
Carmen P. Ortega-Santos, Ana J. Pinto, Mary O. Whipple, Zhaoxing Pan, Kristen E. Boyle, Edward L. Melanson, Kevin S. Masters, Daniel H. Bessesen, Audrey Bergouignan
Publikováno v:
International Journal of Clinical Trials. 10:34-44
Background: To compare the acute and chronic effects of frequent, short physical activity (PA) bouts spread throughout the day to a time-matched intervention consisting in a single continuous daily bout of PA on glucose control and potential underlyi
Autor:
Lauren E. Gyllenhammer, Allison M. Duensing, Madeline Rose Keleher, Katerina Kechris, Dana Dabelea, Kristen E. Boyle
Publikováno v:
Obesity. 31:37-42
In human studies, new model systems are needed for improved mechanistic investigation of developmental predisposition for metabolic disease but also to serve as benchmarks in early life prevention or intervention efforts. In this regard, human infant