Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Kristen E Jurusik"'
Autor:
Dana Knecht, Samuel C. Blackman, Kristen E Jurusik, Lauren E. Richards-Peterson, Peter D. Gorycki, Jerry L. Adams, Donna Mamaril-Fishman, David A. Bershas, Noelia Nebot, Royce A. Morrison, Stanley W. Carson, Daniele Ouellet
Publikováno v:
Drug Metabolism and Disposition. 41:2215-2224
A phase I study was conducted to assess the metabolism and excretion of [(14)C]dabrafenib (GSK2118436; N-{3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzene sulfonamide, methanesulfonate salt), a
Autor:
Esaie Pierre, Christopher A. Evans, Chester L. Bowen, Hermes Licea-Perez, Alan H. Stokes, Joseph Siple, Kristen E Jurusik, Molly Z Karlinsey, Neil Spooner, Jim Kenney
Publikováno v:
Bioanalysis. 5(9)
Background: A novel device and procedure for the collection and isolation of microvolumes of plasma have been developed and two pilot rodent PK studies have been completed. Results: This method involves collection of blood into a plastic-wrapped, EDT