Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kristen E Bower"'
Autor:
Kristen E. Bower, Albert E. Beuscher, Bin Zhou, Hao Jiang, Andrey A. Bobkov, Peter K. Vogt, Arthur J. Olson
Publikováno v:
Molecular Pharmacology. 76:491-502
Many human cancers show constitutive or amplified expression of the transcriptional regulator and oncoprotein Myc, making Myc a potential target for therapeutic intervention. Here we report the down-regulation of Myc activity by reducing the availabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::640dc2c2f027cadb01d7d2c6dd1c327a
https://doi.org/10.1124/mol.109.054858
https://doi.org/10.1124/mol.109.054858
Autor:
John B. Hogenesch, Josephine N. Harada, Peter K. Vogt, Scott Callaway, Casey Laris, Christian G. Nelson, Sumit K. Chanda, Kristen E. Bower, Anthony P. Orth
Publikováno v:
Genome Research. 15:1136-1144
Over the last decade, the rapid expansion in genome sequence has led to the identification of genes at a rate that far exceeds the capacity to understand their function (Adams et al. 2000; Lander et al. 2001; Venter et al. 2001; Waterston et al. 2002
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8d05235a7406f3bd8b9d2d44f4ac9a
https://doi.org/10.1101/gr.3889305
https://doi.org/10.1101/gr.3889305
Publikováno v:
Oncogene. 23:8805-8814
p21SNFT (21 kDa small nuclear factor isolated from T cells) is a human basic leucine zipper transcription factor that can repress AP-1-mediated transcription. We show here that overexpression of p21SNFT in HepG2 cells leads to repression of matrix me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f324af6157ea733d3b5ef8582865e8
https://doi.org/10.1038/sj.onc.1208109
https://doi.org/10.1038/sj.onc.1208109
Autor:
Kristen E Bower, Ryan Preston, Emily Corner, Robert E. Murphy, Arvind G. Kinhikar, Xia Cao, Zemeda W Ainekulu, Aakash B Datt, Steven Pirie-Shepherd, Lioudmila Campbell, Gang Chen, Venkata Doppalapudi, Joselyn Del Rosario, Hanhua Huang, Bryan Oates, Rodney W. Lappe, Son Lam, Trina Osothprarop, Nancy Levin, Curt Bradshaw, Gary Woodnutt, Julie A Hoye, Judith Jimenez
Publikováno v:
Journal of medicinal chemistry. 54(5)
Novel phage-derived peptides are the first reported molecules specifically targeting human placental growth factor 1 (PlGF-1). Phage data enabled peptide modifications that decreased IC(50) values in PlGF-1/VEGFR-1 competition ELISA from 100 to 1 μM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d778774e40714032c80844e89f7bc95
https://pubmed.ncbi.nlm.nih.gov/21280651
https://pubmed.ncbi.nlm.nih.gov/21280651
Publikováno v:
Chembiochem : a European journal of chemical biology. 6(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc05d1f44aabce0fa80412e48c02c643
https://pubmed.ncbi.nlm.nih.gov/15880659
https://pubmed.ncbi.nlm.nih.gov/15880659
Autor:
Lac V. Lee, Peter K. Vogt, Jin Shi, Steven J. Sucheck, Douglass Wu, Fu-Sen Liang, Chi-Huey Wong, Kristen E. Bower
Publikováno v:
Journal of the American Chemical Society. 126(15)
The anthrax lethal factor (LF), a Zn-dependent endopeptidase, is considered the dominant virulence factor of anthrax. Because pharmacological inhibition of the catalytic activity of LF is considered a plausible mechanism for preventing the lethality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9901c256dd567dce4cb36f55219b26d9
https://pubmed.ncbi.nlm.nih.gov/15080670
https://pubmed.ncbi.nlm.nih.gov/15080670
Publikováno v:
The Journal of biological chemistry. 277(38)
p21(SNFT) (21-kDa small nuclear factor isolated from T cells) is a novel human protein of the basic leucine zipper family. The overexpression of p21(SNFT) leads to the significant and specific repression of transcription from the interleukin-2 promot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f595a7192f09680330d7d3a4f7c2deb8
https://pubmed.ncbi.nlm.nih.gov/12087103
https://pubmed.ncbi.nlm.nih.gov/12087103