Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kristen D. Nordham"'
Autor:
Kristen D Nordham, Scott Ninokawa, Ayman Ali, Jacob M Broome, Scott McCraney, John T Simpson, Danielle Tatum, Olan Jackson-Weaver, Sharven Taghavi, Patrick McGrew, Juan Duchesne
Publikováno v:
Journal of Endovascular Resuscitation and Trauma Management, Vol 7, Iss 1 (2023)
Background: The effects of resuscitative endovascular balloon occlusion of the aorta (REBOA) on progression of traumatic brain injury (TBI) are unclear. Two hypotheses prevail: increased mean arterial pressure may improve cerebral perfusion, or cause
Externí odkaz:
https://doaj.org/article/b531af7bd4ed47e3878e170f38a55441
Autor:
Alejandra N. Martinez, Giovane G. Tortelote, Crissey L. Pascale, Isabella G. McCormack, Kristen D. Nordham, Natalie J. Suder, Mitchell W. Couldwell, Aaron S. Dumont
Publikováno v:
Stroke. 53:2647-2657
Background: The circle of Willis (CoW) is the most common location for aneurysms to form in humans. Although the major cell types of the intracranial vasculature are well known, the heterogeneity and relative contributions of the different cells in h
Publikováno v:
Panamerican Journal of Trauma, Critical Care & Emergency Surgery. 10:95-100
Autor:
James M. Haan, Ian Tfrin, Danielle Tatum, Matthew R. Noorbakhsh, Matthew M. Carrick, Thomas J. Schroeppel, Lawrence Lottenberg, Adrian W. Ong, John D. Berne, Sharven Taghavi, Kristen D. Nordham, Dalier Rodriguez Mederos, Marie Crandall, Robert Borrego, Daniel C. Cullinane, Asanthi Ratnasekera, Brian K. Yorkgitis, Frances Hite Philps, Thomas Z. Hayward, Andy J Kerwin, Kelly L. Lightwine, Mellody Bellora, Kaushik Mukherjee, Nikolay Bugaev
Publikováno v:
Journal of Trauma and Acute Care Surgery. 92:88-92
BACKGROUND Trauma teams are often faced with patients on antithrombotic drugs, which is challenging when bleeding occurs. We sought to compare the effects of different antithrombotic medications on head injury severity and hypothesized that antithrom
Autor:
Mary K. Bryant, Leah C. Tatebe, Nandini Rajaram Siva, Pascal O. Udekwu, Mary Wurzelmann, Marie L. Crandall, Yohan Diaz Zuniga, Virginia Tran, Ariel Santos, Cassandra Krause, David Turay, Kristen D. Nordham, Sharven Taghavi, Elizabeth B. Dreesen, Sara Scarlet, Andrew Snyder, Megan Applewhite, Pooja Patel, Thomas J. Schroeppel, Jennifer Rodriquez, Lucy Z. Kornblith, Marissa A. Boeck, Stephanie Bonne, Ann Tufariello, Rebecca G. Maine
Publikováno v:
The journal of trauma and acute care surgery. 93(1)
The US incarcerates more individuals than any other country. Prisoners are the only population guaranteed health care by the US constitution, but little is known about their surgical needs. This multicenter study aimed to describe the acute care surg
Autor:
Brian K, Yorkgitis, Danielle M, Tatum, Sharven, Taghavi, Thomas J, Schroeppel, Matthew R, Noorbakhsh, Frances Hite, Philps, Nikolay, Bugaev, Kaushik, Mukherjee, Mellody, Bellora, Adrian W, Ong, Asanthi, Ratnasekera, Kristen D, Nordham, Matthew M, Carrick, James M, Haan, Kelly L, Lightwine, Lawrence, Lottenberg, Robert, Borrego, Daniel C, Cullinane, John D, Berne, Dalier, Rodriguez Mederos, Thomas Z, Hayward, Andy J, Kerwin, Marie, Crandall
Publikováno v:
The journal of trauma and acute care surgery. 92(1)
Trauma teams are often faced with patients on antithrombotic (AT) drugs, which is challenging when bleeding occurs. We sought to compare the effects of different AT medications on head injury severity and hypothesized that AT reversal would not impro
Autor:
Kristen D. Nordham, Michael T. O’Brien, Piyush Joshi, Vittorio Maglione, Audra M. Foshage, Rachana Nitin, Miles R. Bryan, Aaron B. Bowman, Daniel I.R. Rose, Alba Di Pardo, Michael Aschner, Michael A. Uhouse, Ziyan Zhang
Publikováno v:
Hum Mol Genet
The molecular etiology linking the pathogenic mutations in the Huntingtin (Htt) gene with Huntington’s disease (HD) is unknown. Prior work suggests a role for Htt in neuronal autophagic function and mutant HTT protein disrupts autophagic cargo load
Autor:
Michael Aschner, Aaron B. Bowman, Michael T. O’Brien, Michael A. Uhouse, Kristen D. Nordham, Miles R. Bryan, Daniel I.R. Rose, Piyush Joshi
Publikováno v:
NeuroToxicology. 64:185-194
In a recent study, we found that blocking the protein kinase ataxia telangiectasia mutated (ATM) with the small molecule inhibitor (SMI) KU-55933 can completely abrogate Mn-induced phosphorylation of p53 at serine 15 (p-p53) in human induced pluripot
Autor:
Miles R. Bryan, Michael Aschner, Michael A. Uhouse, Michael T. O’Brien, Filipe Marques Gonçalves, Daniel I.R. Rose, Kristen D. Nordham, Rachana Nitin, Aaron B. Bowman, Piyush Joshi, Audra M. Foshage
Publikováno v:
Mol Neurobiol
Perturbations in insulin/IGF signaling and manganese (Mn(2+)) uptake and signaling have been separately reported in Huntington’s disease (HD) models. Insulin/IGF supplementation ameliorates HD phenotypes via upregulation of AKT, a known Mn(2+)-resp