Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kristen D McKnight"'
Autor:
Christina S Chao, Kristen D McKnight, Kenneth L Cox, Anne L Chang, Seung K Kim, Brian J Feldman
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118449 (2015)
Patients with pancreatic agenesis are born without a pancreas, causing permanent neonatal diabetes and pancreatic enzyme insufficiency. These patients require insulin and enzyme replacement therapy to survive, grow, and maintain normal blood glucose
Externí odkaz:
https://doaj.org/article/4cea7d86148a4d76857c4ae2e8ba05b2
Autor:
Kristen D. McKnight, Benjamin H Liang, Holger Karsunky, Rebecca J. Abergel, Julian A. Rees, Andrew L. Lakes, Camille Ansoborlo, Dahlia D. An, Stacey Gauny
Publikováno v:
Molecular Pharmaceutics. 17:4270-4279
Interest in the use of 225Ac for targeted alpha therapies has increased dramatically over the past few years, resulting in a multitude of new isotope production and translational research efforts. However, 225Ac radioimmunoconjugate (RIC) research is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7e518086e6adae55a27e40562c383af
https://doi.org/10.1021/acs.molpharmaceut.0c00703
https://doi.org/10.1021/acs.molpharmaceut.0c00703
Autor:
Andrew L, Lakes, Dahlia D, An, Stacey S, Gauny, Camille, Ansoborlo, Benjamin H, Liang, Julian A, Rees, Kristen D, McKnight, Holger, Karsunky, Rebecca J, Abergel
Publikováno v:
Molecular pharmaceutics. 17(11)
Interest in the use of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::899f5c028dd129b5ac0df744c8e26659
https://pubmed.ncbi.nlm.nih.gov/33044830
https://pubmed.ncbi.nlm.nih.gov/33044830
Autor:
Amar Ghodasara, Kristen D. McKnight, Ryan T. Rodriguez, Kun Qu, David J. Wong, Xueying Gu, Seung K. Kim, Takuya Sugiyama, Pei Wang, Howard Y. Chang
Publikováno v:
Stem Cells and Development. 21:2273-2287
Embryonic definitive endoderm (DE) generates the epithelial compartment of vital organs such as liver, pancreas, and intestine. However, purification of DE in mammals has not been achieved, limiting the molecular "definition" of endoderm, and hinderi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b356b84dfa68367bab2f342df946eb73
https://doi.org/10.1089/scd.2011.0416
https://doi.org/10.1089/scd.2011.0416
Publikováno v:
Cell Stem Cell. 6:300-308
There is considerable excitement about harnessing the potential of human stem cells to replace pancreatic islets that are destroyed in type 1 diabetes mellitus. However, our current understanding of the mechanisms underlying pancreas and islet ontoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b0791a0bc978fa113701f603ab680f
https://doi.org/10.1016/j.stem.2010.03.003
https://doi.org/10.1016/j.stem.2010.03.003
Publikováno v:
Developmental Biology. 337:471-481
The definitive endoderm forms during gastrulation and is rapidly transformed into the gut tube which is divided along the anterior-posterior axis into the foregut, midgut, and hindgut. Lineage tracing and genetic analysis have examined the origin of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3661fc4276e5a006630905df0836cfa4
https://doi.org/10.1016/j.ydbio.2009.10.040
https://doi.org/10.1016/j.ydbio.2009.10.040
Autor:
Kenneth L. Cox, Christina S. Chao, Brian J. Feldman, Kristen D. McKnight, Anne L. Chang, Seung K. Kim
Publikováno v:
PloS one, vol 10, iss 2
PLoS ONE
PLoS ONE, Vol 10, Iss 2, p e0118449 (2015)
PLoS ONE
PLoS ONE, Vol 10, Iss 2, p e0118449 (2015)
Patients with pancreatic agenesis are born without a pancreas, causing permanent neonatal diabetes and pancreatic enzyme insufficiency. These patients require insulin and enzyme replacement therapy to survive, grow, and maintain normal blood glucose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051cd17329eefe56651cc56faa746ac5
https://escholarship.org/uc/item/3w0640wc
https://escholarship.org/uc/item/3w0640wc
Publikováno v:
Mechanisms of Development. 119(1):9-20
Nemo-like kinases define a novel family of serine/threonine kinases that are involved in integrating multiple signaling pathways. They are conserved regulators of Wnt/Wingless pathways, which may coordinate Wnt with TGFβ-mediated signaling. Drosophi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06775c76cbebfaa71190d735fd94c7ca
Autor:
Kristen D. McKnight, Regina Nieu, Scott J. Dylla, Kayla Fasano, Hanna Rammoth, Emily Janke, Marybeth A. Pysz, Erica Anderson, Nicole Taylor, Archana Dilip, Holger Karsunky, Sarah L. Fong, Juliet Markeson
Publikováno v:
Cancer Research. 77:4937-4937
Patient derived xenograft (PDX) models of pancreatic cancer provide an excellent platform for understanding human disease, characterizing tumor-initiating cells, and testing of novel therapeutics. Herein, we compared the natural pancreatic microenvir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3fa3e6c83ff7a9bf43ed622c3f87405
https://doi.org/10.1158/1538-7445.am2017-4937
https://doi.org/10.1158/1538-7445.am2017-4937
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 236(10)
Thyrotropin-releasing hormone (TRH) is a well-characterized regulator of the hypothalamic–pituitary–thyroid endocrine axis. Here, we describe the expression of Trh during early embryonic development in the mouse. We find Trh to be highly expresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8999aa396ab8518ca2c37fe8e517a5
https://pubmed.ncbi.nlm.nih.gov/17849455
https://pubmed.ncbi.nlm.nih.gov/17849455