Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kristen Cotoni"'
Publikováno v:
Journal of chromatography. A. 1599
A low ligand density cation exchange (CEX) chromatography resin, Eshmuno® CP-FT resin, was investigated for the removal of aggregates from monoclonal antibody (mAb) feeds using a continuous loading process. Removing mAb aggregates with a CEX resin u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de20cd28a5faa351e16efe7e213c89d9
https://pubmed.ncbi.nlm.nih.gov/31084900
https://pubmed.ncbi.nlm.nih.gov/31084900
Autor:
Melissa Holstein, Ronald Tuccelli, John Caulmare, Patricia Greenhalgh, Kristen Cotoni, Lori Mullin, Christopher Gillespie
Publikováno v:
Biotechnology Journal
Viral inactivation plays a critical role in assuring the safety of monoclonal antibody (mAb) therapeutics. Traditional viral inactivation involves large holding tanks in which product is maintained at a target low pH for a defined hold time, typicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4185df20eaac951047b6f4d6cabe1e
Autor:
Senthilkumar Ramaswamy, Kristen Cotoni, Brian Gagnon, Neil Soice, Chen Wang, Nanying Bian, Joaquin Umana, Kwok-Shun Cheng
Publikováno v:
Journal of Chromatography A. 1155:74-84
Agarose-based anion-exchangers (e.g. quaternary amine, Q) have been widely used in monoclonal antibody flow-through purification to remove trace levels of impurities. Such media are often packed in a large column and the operation is usually robust b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d33a9cc5b1031d2fa8167a480442b45
https://doi.org/10.1016/j.chroma.2007.04.030
https://doi.org/10.1016/j.chroma.2007.04.030