Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kristen B. Farrell"'
Publikováno v:
PLoS ONE, Vol 19, Iss 5 (2024)
Externí odkaz:
https://doaj.org/article/6ff35d4eadd54ba684ffc7aa6bda3352
Publikováno v:
Bone Reports, Vol 9, Iss , Pp 47-60 (2018)
Bones provide essential functions and are sites of unique biochemistry and specialized cells, but can also be sites of disease. The treatment of bone disorders and neoplasia has presented difficulties in the past, and improved delivery of drugs to bo
Externí odkaz:
https://doaj.org/article/22c276b4b5674c1284daf05148ff0c7b
Autor:
Kristen B. Farrell, Douglas H. Thamm
Publikováno v:
Cancer Research. 83:6233-6233
Omacetaxine mepesuccinate (OMX), also known as homoharringtonine, is a protein translation inhibitor approved for use in chronic myeloid leukemia. Recent studies suggest OMX may be effective against other cancer types with high rates of protein trans
Publikováno v:
Bioconjug Chem
Patients with cancer-induced bone disease, including primary bone cancers such as osteosarcoma (OS) and metastases from other tissues of origin, present a high unmet medical need. We present a potential therapeutic approach built upon a proven bone-t
Publikováno v:
Bone Reports
Bone Reports, Vol 9, Iss, Pp 47-60 (2018)
Bone Reports, Vol 9, Iss, Pp 47-60 (2018)
Bones provide essential functions and are sites of unique biochemistry and specialized cells, but can also be sites of disease. The treatment of bone disorders and neoplasia has presented difficulties in the past, and improved delivery of drugs to bo
Autor:
Santiago M. Di Pietro, Seth McDonald, Olve B. Peersen, Kristen B. Farrell, Andrew K. Lamb, Colette R. Worcester
Publikováno v:
The Journal of Cell Biology
Actin-capping protein is a key component of the actin cytoskeleton at sites of clathrin-mediated endocytosis. Farrell et al. show that a newly discovered component of the endocytic machinery belongs to the dynein light chain family and regulates the
Publikováno v:
Genetics. 201:1061-1070
Despite the importance of clathrin-mediated endocytosis (CME) for cell biology, it is unclear if all components of the machinery have been discovered and many regulatory aspects remain poorly understood. Here, using Saccharomyces cerevisiae and a flu
Publikováno v:
Traffic. 16:379-397
During clathrin-mediated endocytosis (CME), actin assembly provides force to drive vesicle internalization. Members of the Wiskott-Aldrich syndrome protein (WASP) family play a fundamental role stimulating actin assembly. WASP family proteins contain
Publikováno v:
Traffic (Copenhagen, Denmark). 16(4)
During clathrin-mediated endocytosis (CME), actin assembly provides force to drive vesicle internalization. Members of the Wiskott–Aldrich syndrome protein (WASP) family play a fundamental role stimulating actin assembly. WASP family proteins conta
Autor:
Farrell, Kristen B.1 (AUTHOR) Kristen.farrell@colostate.edu, Das, Sunetra1 (AUTHOR), Nordeen, Steven K.2 (AUTHOR), Lambert, James R.2 (AUTHOR), Thamm, Douglas H.1 (AUTHOR)
Publikováno v:
PLoS ONE. 5/21/2024, Vol. 19 Issue 5, p1-16. 16p.