Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kristen A. Malkus"'
Autor:
Kristen A. Malkus, Harry Ischiropoulos
Publikováno v:
Neurobiology of Disease, Vol 46, Iss 3, Pp 732-744 (2012)
In neurodegenerative diseases, it remains unclear why certain brain regions are selectively vulnerable to protein aggregation. In transgenic mice expressing human A53T α-synuclein, the brainstem and spinal cord develop the most prominent α-synuclei
Externí odkaz:
https://doaj.org/article/edde2c4bc69d41a990e1cde605001eff
Autor:
Harry Ischiropoulos, Benoit I. Giasson, Kristen A. Malkus, Richard Lightfoot, Danielle Emille Mor, Neal S. Gould
Publikováno v:
Journal of Biological Chemistry. 289:7929-7934
α-Synuclein aggregation is central to the pathogenesis of several brain disorders. However, the native conformations and functions of this protein in the human brain are not precisely known. The native state of α-synuclein was probed by gel filtrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b67342c05b7e0276a890ba3f183acf74
https://doi.org/10.1074/jbc.c113.538249
https://doi.org/10.1074/jbc.c113.538249
Autor:
Edward S. Brodkin, Ted Abel, Holly C. Dow, Andrew H. Fairless, Michele L. Edelmann, Konrad Talbot, Hongzhe Li, Kristen A. Malkus, Monica M. Toledo, Steven E. Arnold
Publikováno v:
Brain Research. 1230:211-217
The behavioral manifestations of autism, including reduced sociability (reduced tendency to seek social interaction), may be related to underdevelopment of the corpus callosum (CC). The BALB/cJ inbred mouse strain is a useful model system for testing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2977d01d288b586ded680a5687470a70
https://doi.org/10.1016/j.brainres.2008.07.025
https://doi.org/10.1016/j.brainres.2008.07.025
Publikováno v:
Molecular Neurodegeneration, Vol 4, Iss 1, p 24 (2009)
Molecular Neurodegeneration
Molecular Neurodegeneration
While numerous hypotheses have been proposed to explain the molecular mechanisms underlying the pathogenesis of neurodegenerative diseases, the theory of oxidative stress has received considerable support. Although many correlations have been establi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec1fe23747b56ed236fedc701e37e47a
http://www.molecularneurodegeneration.com/content/4/1/24
http://www.molecularneurodegeneration.com/content/4/1/24