Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Kristen A. Keefe"'
Autor:
Danielle M. Giangrasso, Kaliana M. Veros, Maureen M. Timm, Peter J. West, Karen S. Wilcox, Kristen A. Keefe
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
The shift from drug abuse to addiction is considered to arise from the transition between goal-directed and habitual control over drug behavior. Habitual responding for appetitive and skill-based behaviors is mediated by potentiated glutamate signali
Externí odkaz:
https://doaj.org/article/bec789625f6e4497aecb95f50191491e
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
The recently developed DJ-1 knockout (KO) rat models the DJ-1 (or PARK7) loss-of-function mutation responsible for one form of early-onset familial Parkinson's disease (PD). Prior studies demonstrate that DJ-1 KO rats present progressive dopamine (DA
Externí odkaz:
https://doaj.org/article/156603025db145a4a4c194d9bb178f15
Autor:
Kristen A. Keefe, Anne S. Gibson
Publikováno v:
Handbook of Neurotoxicity ISBN: 9783031150791
Handbook of Neurotoxicity ISBN: 9783030715199
Handbook of Neurotoxicity
Handbook of Neurotoxicity ISBN: 9783030715199
Handbook of Neurotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c81bffa21feb30a2042d088eeadfdf
https://doi.org/10.1007/978-3-031-15080-7_243
https://doi.org/10.1007/978-3-031-15080-7_243
Autor:
Anne S. Gibson, Kristen A. Keefe
Publikováno v:
Handbook of Neurotoxicity ISBN: 9783031150791
Handbook of Neurotoxicity ISBN: 9783030715199
Handbook of Neurotoxicity
Handbook of Neurotoxicity ISBN: 9783030715199
Handbook of Neurotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2975a6a650e5cc12d5890814639801c1
https://doi.org/10.1007/978-3-031-15080-7_190
https://doi.org/10.1007/978-3-031-15080-7_190
Autor:
Eva Vigato, Nilesh W. Gaikwad, Ryan D. Farero, Kristen A. Keefe, Randall T. Peterson, Roberto Cadeddu, Gabriele Floris, Tejia Zhang, Gabriel D. Bossé, Suhjung J. Lee, Marco Bortolato, Paul E. M. Phillips
Publikováno v:
J Clin Invest
Opioid use disorder (OUD) has become a leading cause of death in the United States, yet current therapeutic strategies remain highly inadequate. To identify potential treatments for OUD, we screened a targeted selection of over 100 drugs using a rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f3c070ce8a5221dbc5b2042259a29a
https://europepmc.org/articles/PMC8121512/
https://europepmc.org/articles/PMC8121512/
Autor:
Matthew D Riedy, Kristen A Keefe
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72883 (2013)
Drug-seeking behavior elicited by drug-associated cues contributes to relapse in addiction; however, whether relapse elicited by drug-associated conditioned reinforcers (CR) versus discriminative stimuli (DS) involves distinct or overlapping neuronal
Externí odkaz:
https://doaj.org/article/e89afebb1bd749f7a8e721c64ae35bb2
Autor:
Ryan D. Farero, Nilesh W. Gaikwad, Marco Bortolato, Paul E. M. Phillips, Gabriele Floris, Randall T. Peterson, Kristen A. Keefe, Roberto Cadeddu, Janet S. Lee, Eva Vigato, Gabriel D. Bossé, Tejia Zhang
Opioid use disorder (OUD) has become a leading cause of death in the US, yet current therapeutic strategies remain highly inadequate. To identify novel potential treatments for OUD, we screened a targeted selection of over 100 drugs, using a recently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b653ecd4a91008bceecf1045376e2ee3
https://doi.org/10.1101/2020.09.15.291609
https://doi.org/10.1101/2020.09.15.291609
Publikováno v:
European Journal of Neuroscience. 45:1418-1430
Opioid signaling in the nucleus accumbens shell (sNAcc) has been implicated in hedonic feeding and binge eating behavior. The sNAcc projects to the lateral hypothalamus (LH), and this pathway has been suggested to modulate palatability-driven feeding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::254ed32081aa3e68e8926077b73d55e1
https://doi.org/10.1111/ejn.13579
https://doi.org/10.1111/ejn.13579
Publikováno v:
The Journal of Physiology. 595:1393-1412
Ethanol, like other drugs of abuse, has both rewarding and aversive properties. Previous work suggests that sensitivity to ethanol's aversive effects negatively modulates voluntary alcohol intake and thus may be important in vulnerability to developi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53e966aa74794cf990c2242628d1c6b1
https://doi.org/10.1113/jp272994
https://doi.org/10.1113/jp272994
Publikováno v:
Psychopharmacology
Rationale Ethanol has rewarding and aversive properties, and the balance of these properties influences voluntary ethanol consumption. Preclinical and clinical evidence show that the aversive properties of ethanol limit intake. The neural circuits un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16022e2a6f1793215bda19fce6428128
https://doi.org/10.1007/s00213-016-4406-7
https://doi.org/10.1007/s00213-016-4406-7