Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kristen A. Jeffries"'
Autor:
Kristen A. Jeffries, Zhen Fan, Xiuxiu Sun, Gabriela M. Olmedo, Wei Zhao, Matthew Mattia, Ed Stover, Elizabeth Baldwin, John A. Manthey, Andrew Breksa, Jinhe Bai, Anne Plotto
Publikováno v:
Frontiers in Horticulture, Vol 3 (2024)
IntroductionCitrus hybrids with Poncirus trifoliata L. Raf. introgression have gained interest due to their tolerance to Huanglongbing (HLB), a devastating disease for Florida citrus agriculture. While these hybrids inherit disease tolerance from P.
Externí odkaz:
https://doaj.org/article/ea15b13388c2491ea99a46aea740f2e6
Publikováno v:
Foods, Vol 12, Iss 1, p 209 (2023)
Winter melon fruits were grown in the field using anaerobic soil disinfestation (ASD) and conventional fertilizer alone as the control treatment. Fruits were harvested and stored at 20 °C for 120 d, the juice was processed on day one and day 120, an
Externí odkaz:
https://doaj.org/article/f08faa496c004239876c7aafb4a8a208
Autor:
Baharan Fekry, Kristen A. Jeffries, Amin Esmaeilniakooshkghazi, Zdzislaw M. Szulc, Kevin J. Knagge, David R. Kirchner, David A. Horita, Sergey A. Krupenko, Natalia I. Krupenko
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Ceramides are important participants of signal transduction, regulating fundamental cellular processes. Here authors show that C16-ceramide binds to the tumor suppressor p53, disrupts its interaction with MDM2 and facilitates p53 accumulation and act
Externí odkaz:
https://doaj.org/article/c8bb01b97ed94da88a335f1f599d147e
Autor:
Kristen A. Jeffries, Daniel R. Dempsey, Emma K. Farrell, Ryan L. Anderson, Gabrielle J. Garbade, Tatyana S. Gurina, Imran Gruhonjic, Carly A. Gunderson, David J. Merkler
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 5, Pp 781-790 (2016)
Long-chain fatty acid amides are signaling lipids found in mammals and other organisms; however, details of the metabolic pathways for the N-acylglycines and primary fatty acid amides (PFAMs) have remained elusive. Heavy-labeled precursor and subtrac
Externí odkaz:
https://doaj.org/article/f14b6dd5739e48668063e7ea222b40e8
Autor:
Emma K. Farrell, Yuden Chen, Muna Barazanji, Kristen A. Jeffries, Felipe Cameroamortegui, David J. Merkler
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 2, Pp 247-256 (2012)
Primary fatty acid amides (PFAM) are important signaling molecules in the mammalian nervous system, binding to many drug receptors and demonstrating control over sleep, locomotion, angiogenesis, and many other processes. Oleamide is the best-studied
Externí odkaz:
https://doaj.org/article/11126f0854e5475391b2039d997d882a
Autor:
Sophie C. Deterre, Kristen A. Jeffries, Greg McCollum, Ed Stover, Clotilde Leclair, John A. Manthey, Jinhe Bai, Elizabeth A. Baldwin, Smita Raithore, Anne Plotto
Publikováno v:
Journal of Food Science. 88:1684-1699
Publikováno v:
Foods (Basel, Switzerland). 12(1)
Winter melon fruits were grown in the field using anaerobic soil disinfestation (ASD) and conventional fertilizer alone as the control treatment. Fruits were harvested and stored at 20 °C for 120 d, the juice was processed on day one and day 120, an
Publikováno v:
The FASEB Journal. 33
Ceramide is a key bioeffector in cellular adaptation to stress, and increased ceramide generation often functions as a pro-apoptotic signal. Another key mediator of apoptosis, the p53 tumor suppres...
Publikováno v:
Chem Biol Interact
Epidemiological evidence underscores alcohol consumption as a strong risk factor for multiple cancer types, with liver cancer being most commonly associated with alcohol intake. While mechanisms linking alcohol consumption to malignant tumor developm
Autor:
Natalia I. Krupenko, Sergey A. Krupenko, Kevin J. Knagge, David R. Kirchner, Baharan Fekry, Zdzislaw M. Szulc, Amin Esmaeilniakooshkghazi, David A. Horita, Kristen A. Jeffries
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Ceramides are important participants of signal transduction, regulating fundamental cellular processes. Here we report the mechanism for activation of p53 tumor suppressor by C16-ceramide. C16-ceramide tightly binds within the p53 DNA-binding domain