Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kristel Paola Ramirez Valdez"'
Autor:
Kazuki Tanaka, Takeo Kuwata, Muntasir Alam, Gilad Kaplan, Shokichi Takahama, Kristel Paola Ramirez Valdez, Anna Roitburd-Berman, Jonathan M. Gershoni, Shuzo Matsushita
Publikováno v:
Retrovirology, Vol 14, Iss 1, Pp 1-15 (2017)
Abstract Background The CD4-induced (CD4i) epitopes in gp120 includes the co-receptor binding site, which are formed and exposed after interaction with CD4. Monoclonal antibodies (mAbs) to the CD4i epitopes exhibit limited neutralizing activity becau
Externí odkaz:
https://doaj.org/article/ac5e67be97974c28a2b3fa0db7197e64
Autor:
Shuzo Matsushita, Kazuhisa Yoshimura, Kazuki Tanaka, Muntasir Alam, Yasuhiro Maruta, Takeo Kuwata, Kristel Paola Ramirez Valdez
Publikováno v:
Virology. 475:187-203
Antibodies with modest neutralizing activity and narrow breadth are commonly elicited in HIV-1. Here, we evaluated the complementary and synergistic activities of a set of monoclonal antibodies (MAb) isolated from a single patient, directed to V3, CD
Autor:
Shokichi Takahama, Anna Roitburd-Berman, Shuzo Matsushita, Gilad Kaplan, Kristel Paola Ramirez Valdez, Muntasir Alam, Jonathan M. Gershoni, Takeo Kuwata, Kazuki Tanaka
Publikováno v:
Retrovirology, Vol 14, Iss 1, Pp 1-15 (2017)
Retrovirology
Retrovirology
Background The CD4-induced (CD4i) epitopes in gp120 includes the co-receptor binding site, which are formed and exposed after interaction with CD4. Monoclonal antibodies (mAbs) to the CD4i epitopes exhibit limited neutralizing activity because of res
Autor:
Nobutaka Fujii, Kristel Paola Ramirez Valdez, Kazuya Shimura, Takeo Kuwata, Shinya Oishi, Muntasir Alam, Hironori Sato, Masao Matsuoka, Yasuhiro Maruta, Shuzo Matsushita, Kazuki Tanaka, Masaru Yokoyama
Publikováno v:
Retrovirology
Background HIV-1 typically develops resistance to any single antiretroviral agent. Combined anti-retroviral therapy to reduce drug-resistance development is necessary to control HIV-1 infection. Here, to assess the utility of a combination of antibod
Autor:
Muntasir Alam, Kazuki Tanaka, Yoshiaki Suwa, Shuzo Matsushita, Yasuhiro Maruta, Yoshika Egami, Takeo Kuwata, Hiroshi Morioka, Kristel Paola Ramirez Valdez
Publikováno v:
Japanese journal of infectious diseases. 69(5)
The V3 loop in the envelope (Env) of HIV-1 is one of the major targets of neutralizing antibodies. However, this antigen is hidden inside the Env trimer in most isolates and is fully exposed only during CD4-gp120 interaction. Thus, primary HIV-1 isol
Publikováno v:
Reports in Advances of Physical Sciences, Vol 2, Iss 1, Pp 1850001-1-1850001-31 (2018)
Sensor-based diagnostics are increasing rapidly and in clinics, they can transform the health care as they will be in use out of clinics as well, namely, by the non-clinicians and people without expertise. The trade-off between the advantages and dis
Publikováno v:
Reports in Advances of Physical Sciences, Vol 2, Iss 1, Pp 1850003-1-1850003-25 (2018)
Evaluating the efficacy and accuracy of clinical reasoning and distinguishing between complications and medical errors is a difficult task. However, it seems to be an even more difficult task to provide models for systematically reporting and reducin