Výsledky vyhledávání - "Kristel C. Tjandra"

Akademický článek

Growth independent morphometric machine learning workflow for single-cell antimicrobial susceptibility testing of Klebsiella pneumoniae to meropenem

Autor: Kristel C. Tjandra, Nikhil Ram-Mohan, Manuel Roshardt, Elizabeth J. Zudock, Zhaonan Qu, Kathleen E. Mach, Okyaz Eminaga, Joseph C. Liao, Samuel Yang, Pak Kin Wong

Publikováno v: Frontiers in Imaging, Vol 3 (2024)

IntroductionMultidrug-resistant Enterobacteriaceae are among the most urgent global public health threats associated with various life-threatening infections. In the absence of a rapid method to identify antimicrobial susceptibility, empirical use of

Externí odkaz: https://doaj.org/article/87af7f06bb5a430db2005c1d00c49a61

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Akademický článek

Diagnosis of Bloodstream Infections: An Evolution of Technologies towards Accurate and Rapid Identification and Antibiotic Susceptibility Testing

Autor: Kristel C. Tjandra, Nikhil Ram-Mohan, Ryuichiro Abe, Marjan M. Hashemi, Jyong-Huei Lee, Siew Mei Chin, Manuel A. Roshardt, Joseph C. Liao, Pak Kin Wong, Samuel Yang

Publikováno v: Antibiotics, Vol 11, Iss 4, p 511 (2022)

Bloodstream infections (BSI) are a leading cause of death worldwide. The lack of timely and reliable diagnostic practices is an ongoing issue for managing BSI. The current gold standard blood culture practice for pathogen identification and antibioti

Externí odkaz: https://doaj.org/article/4d76dad70e554984b39b99e618f77779

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Rapid Molecular Phenotypic Antimicrobial Susceptibility Test for Neisseria gonorrhoeae Based on Propidium Monoazide Viability PCR

Autor: Kristel C. Tjandra, Nikhil Ram-Mohan, Ryuichiro Abe, Tza-Huei Wang, Samuel Yang

Publikováno v: ACS Infectious Diseases. 9:1160-1167

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::38b21bdb90fcfd4f35a1846043c024f2
https://doi.org/10.1021/acsinfecdis.3c00096

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Tuning the Mechanical Properties of Multiarm RAFT-Based Block Copolyelectrolyte Hydrogels via Ionic Cross-Linking for 3D Cell Cultures

Autor: Duyen H. T. Nguyen, Robert H. Utama, Kristel C. Tjandra, Panthipa Suwannakot, Eric Y. Du, Maria Kavallaris, Richard D. Tilley, J. Justin Gooding

Publikováno v: Biomacromolecules. 24:57-68

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f98fcdb9f71961e742caf88beb42db9e
https://doi.org/10.1021/acs.biomac.2c00632

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Rapid molecular phenotypic antimicrobial susceptibility test forNeisseria gonorrhoeaebased on propidium monoazide viability PCR

Autor: Kristel C. Tjandra, Nikhil Ram-Mohan, Ryuichiro Abe, Tza-Huei Wang, Samuel Yang

Neisseria gonorrhoeae(NG) is an urgent threat to antimicrobial resistance (AMR) worldwide. NG has acquired rapid resistance to all previously recommended treatments leaving ceftriaxone monotherapy as the first and last line of therapy for uncomplicat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62a0f407e44756c406858c741a4dcf7e
https://doi.org/10.1101/2023.03.01.530513

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MorphoAST – A Machine Learning Workflow for Sub-Doubling Time Single Cell Antimicrobial Susceptibility Testing

Autor: Kristel C. Tjandra, Nikhil Ram-Mohan, Manuel Roshardt, Zhaonan Qu, Elizabeth Zudock, Kathleen E. Mach, Okyaz Eminaga, Joseph C. Liao, Samuel Yang, Pak Kin Wong

BackgroundMultidrug-resistant bacteria are among the most urgent global public health threats. Rapid determination of antimicrobial resistance in a single bacterium is a major clinical unmet need in the diagnosis of bacterial infections.MethodsBy cap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6a43447db91adeb4a11bacde591c6db9
https://doi.org/10.1101/2022.11.03.515093

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A covalently crosslinked bioink for multi-materials drop-on-demand 3D bioprinting of three-dimensional cell cultures

Autor: Robert H. Utama, Aidan P. O’Mahony, Vincent T. G. Tan, Andrew Sexton, J. Justin Gooding, Maria Kavallaris, Julio C. C. Ribeiro, Duyen H. T. Nguyen, Kristel C Tjandra

In vitro three-dimensional (3D) cell models have been accepted to better recapitulate aspects of in vivo organ environment than 2D cell culture. Currently, the production of these complex in vitro 3D cell models with multiple cell types and microenvi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::48f21dde37ef85681f0f2c787108ac63
https://doi.org/10.1101/2021.02.18.431759

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Modulating the Selectivity and Stealth Properties of Ellipsoidal Polymersomes through a Multivalent Peptide Ligand Display

Autor: Yi Ju, Martina H. Stenzel, Chin Ken Wong, Sheilajen Alcantara, Hannah G. Kelly, Maria Kavallaris, Frank Caruso, Kristel C Tjandra, Pall Thordarson, Stephen J. Kent, Chelsea R. Forest, Joshua A. McCarroll

Publikováno v: Advanced Healthcare Materials. 9:2000261

There is a need for improved nanomaterials to simultaneously target cancer cells and avoid non-specific clearance by phagocytes. An ellipsoidal polymersome system is developed with a unique tunable size and shape property. These particles are functio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c28c668bcbe0f18180844a7978b5065
https://doi.org/10.1002/adhm.202000261

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