Zobrazeno 1 - 10
of 10 632
pro vyhledávání: '"Kristan A"'
Autor:
Samuel B. Anyona, Qiuying Cheng, Sharley A. Wasena, Shamim W. Osata, Yan Guo, Evans Raballah, Ivy Hurwitz, Clinton O. Onyango, Collins Ouma, Philip D. Seidenberg, Benjamin H. McMahon, Christophe G. Lambert, Kristan A. Schneider, Douglas J. Perkins
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract This study on severe malarial anemia (SMA: Hb < 6.0 g/dL), a leading global cause of childhood morbidity and mortality, compares the entire expressed whole blood host transcriptome between Kenyan children (3-48 mos.) with non-SMA (Hb ≥ 6.0
Externí odkaz:
https://doaj.org/article/2622e5cda8f8454d886f8c9629fbe735
Autor:
Richard Vogel, Tobias Schlosser, Robert Manthey, Marc Ritter, Matthias Vodel, Maximilian Eibl, Kristan Alexander Schneider
Publikováno v:
Machine Learning and Knowledge Extraction, Vol 6, Iss 2, Pp 800-826 (2024)
Background. The importance of explainable artificial intelligence and machine learning (XAI/XML) is increasingly being recognized, aiming to understand how information contributes to decisions, the method’s bias, or sensitivity to data pathologies.
Externí odkaz:
https://doaj.org/article/b51912eb878c4c5ba52f5ad1cc8640ff
Publikováno v:
Frontiers in Malaria, Vol 2 (2024)
IntroductionThe presence of multiple genetically distinct variants (lineages) within an infection (multiplicity of infection, MOI) is common in infectious diseases such as malaria. MOI is considered an epidemiologically and clinically relevant quanti
Externí odkaz:
https://doaj.org/article/d4cbb92fab524232a6bcf2e62e7a370f
Autor:
Maureen McHugo, Maxwell J. Roeske, Simon N. Vandekar, Kristan Armstrong, Suzanne N. Avery, Stephan Heckers
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Hippocampal volume is smaller in schizophrenia, but it is unclear when in the illness the changes appear and whether specific regions (anterior, posterior) and subfields (CA1, CA2/3, dentate gyrus, subiculum) are affected. Here, we used a hi
Externí odkaz:
https://doaj.org/article/a79ed7caa4b5491280bb938a50fdd48b
Autor:
Clinton O. Onyango, Samuel B. Anyona, Ivy Hurwitz, Evans Raballah, Sharely A. Wasena, Shamim W. Osata, Philip Seidenberg, Benjamin H. McMahon, Christophe G. Lambert, Kristan A. Schneider, Collins Ouma, Qiuying Cheng, Douglas J. Perkins
Publikováno v:
Pathogens, Vol 13, Iss 10, p 867 (2024)
Severe malarial anemia (SMA, Hb < 6.0 g/dL) is a leading cause of childhood morbidity and mortality in holoendemic Plasmodium falciparum transmission zones. This study explored the entire expressed human transcriptome in whole blood from 66 Kenyan ch
Externí odkaz:
https://doaj.org/article/c2a91df8a42149638015f16c33cc3c13
Autor:
Amrita Ladwa, Omar Elghawy, Anneke Schroen, Kristan Abernathy, Jenna Schlefman, Patrick Dillon
Publikováno v:
Case Reports in Oncology, Vol 16, Iss 1, Pp 1129-1135 (2023)
Metaplastic breast cancer (MpBC) is a rare form of breast malignancy with a poor prognosis and limited treatment guidance. Here, we report on a case of triple-negative MpBC that was successfully treated following the Keynote-522 clinical algorithm us
Externí odkaz:
https://doaj.org/article/9836f39374b74ab0b834f4800f251e9e
Autor:
Clinton O. Onyango, Qiuying Cheng, Elly O. Munde, Evans Raballah, Samuel B. Anyona, Benjamin H. McMahon, Christophe G. Lambert, Patrick O. Onyango, Kristan A. Schneider, Douglas J. Perkins, Collins Ouma
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background Plasmodium falciparum malaria is a leading cause of pediatric morbidity and mortality in holoendemic transmission areas. Severe malarial anemia [SMA, hemoglobin (Hb) G and rs11575837:C > T) and their haplotypes. The prospective ob
Externí odkaz:
https://doaj.org/article/50746c71127340239df9137a3ea899c9
Autor:
Elizabeth Agyare, Joseph Elikem Efui Acolatse, Mavis Puopelle Dakorah, George Akafity, Victoria J Chalker, Owen B Spiller, Kristan Alexander Schneider, Saviour Yevutsey, Nana Benyin Aidoo, Sophia Blankson, Frederick Mensah-Acheampong, Robert Incoom, Amanj Kurdi, Brian Godman, Eric Kofi Ngyedu
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0297626 (2024)
IntroductionAntimicrobial resistance (AMR) is a global threat that necessitates coordinated strategies to improve antibiotic prescribing and reduce AMR. A key activity is ascertaining current prescribing patterns in hospitals to identify targets for
Externí odkaz:
https://doaj.org/article/b81a0806c1c44d4ea113570fb13e2133
Autor:
Meraj Hashemi, Kristan A Schneider
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0287161 (2024)
BackgroundMolecular surveillance of infectious diseases allows the monitoring of pathogens beyond the granularity of traditional epidemiological approaches and is well-established for some of the most relevant infectious diseases such as malaria. The
Externí odkaz:
https://doaj.org/article/7aa5ce3ff04d4ebbb9f8feb2b7878ee2
Autor:
Maryana Bonilla Yanez, Sarah A. Kettlety, James M. Finley, Nicolas Schweighofer, Kristan A. Leech
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Gait biofeedback is a well-studied strategy to reduce gait impairments such as propulsion deficits or asymmetric step lengths. With biofeedback, participants alter their walking to reach the desired magnitude of a specific parameter (the bio
Externí odkaz:
https://doaj.org/article/8ee42423eab8473ca4850e76505687de