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pro vyhledávání: '"Kristal A. Wolfe"'
Autor:
Kristal A. Wolfe, Donald J. Gruol
Publikováno v:
Biochemistry. 29:7958-7966
RU 486 is a synthetic steroid that binds avidly to glucocorticoid receptors without promoting their transformation into activated transcription factors. A significant part of this behavior has been shown to be due to a failure of the RU 486 bound rec
Publikováno v:
Journal of steroid biochemistry. 34(1-6)
Conversion of the glucocorticoid receptor into a DNA-binding protein results in the generation of several distinct receptor subspecies (peaks A-E) which can be resolved by anion exchange chromatography. In vitro, the fraction of the receptor populati
Autor:
Kristal A. Wolfe, Donald J. Gruol
Publikováno v:
Biochemistry. 28(7)
The glucocorticoid receptor can be transformed into a DNA-binding protein by a process that is both hormone and temperature dependent. We have used a modification of the conventional method of anion-exchange chromatography to separate and analyze a v