Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Krista Vincent"'
Autor:
Noémie Villeneuve-Cloutier, Christie Boswell-Patterson, Josée Martineau, Krista Vincent, Andrea Yu, Gail Graham, Julie Richer
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101218- (2024)
Externí odkaz:
https://doaj.org/article/b183a3d146c348688254acd08bca3d45
Autor:
Natalia Volodko, Mohamed Salla, Alaa Zare, El-Arbi Abulghasem, Krista Vincent, Matthew G.K. Benesch, Todd P.W. McMullen, Oliver F. Bathe, Lynne Postovit, Shairaz Baksh
Publikováno v:
Cancers, Vol 8, Iss 6, p 55 (2016)
Epigenetic silencing of RASSF1A is frequently observed in numerous cancers and has been previously reported. The promoter region of RASSF1A is predicted to have 75 CpG sites, and very few studies demonstrate how the methylation of these sites affects
Externí odkaz:
https://doaj.org/article/41bd2b482bc54a0ca2b6c223854a5326
Autor:
Jay Gamma, Erwan Beauchamp, Qiang Liu, Aishwarya Iyer, Megan Yap, Zoulika Zak, Cassidy Ekstrom, Krista Vincent, Joseph Brandwein, Jean C.Y. Wang, Naveen Pemmaraju, Gautam Borthakur, John R. Mackey, Luc G. Berthiaume
Publikováno v:
Blood. 140:3088-3089
Autor:
Christos Patsis, Aakshi Puri, Julia Schueler, Michael Jewer, Daniela F. Quail, Antonis E. Koromilas, Scott D. Findlay, Krista Vincent, Guihua Zhang, Andrea Brumwell, Laura Lee, Bo-Jhih Guan, James Uniacke, Dylan Dieters-Castator, Indrani Dutta, Maria Hatzoglou, Jiahui Liu, Ivan Topisirovic, Zhihua Xu, Matthew Leibovitch, Lynne-Marie Postovit, Kristofferson Tandoc, Gabrielle M. Siegers, Mackenzie Coatham
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Nature Communications
Plasticity of neoplasia, whereby cancer cells attain stem-cell-like properties, is required for disease progression and represents a major therapeutic challenge. We report that in breast cancer cells NANOG, SNAIL and NODAL transcripts manifest multip
Autor:
Matthew Tsang, Andrew Leask, Katherine Quesnel, James Hutchenreuther, Krista Vincent, Lynne-Marie Postovit
Publikováno v:
The American Journal of Pathology. 190:206-221
Tumor stroma resembles a fibrotic microenvironment, being characterized by the presence of myofibroblast-like cancer-associated fibroblasts (CAFs). In wild-type mice injected with melanoma cells, we show that the stem cell transcription factor Sox2 i
Autor:
Maneka A. Perinpanayagam, John R. Mackey, Soon Thye Lim, Manikandan Lakshmanan, Aishwarya Iyer, Anandhkumar Raju, Paul G. Wyatt, Vinay Tergaonkar, Lynne M. Postovit, Kevin D. Read, Krista Vincent, Luc G. Berthiaume, Soo Yong Tan, Megan C. Yap, Jay M. Gamma, Erwan Beauchamp, David W. Gray, Wei-Feng Dong
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Myristoylation, the N-terminal modification of proteins with the fatty acid myristate, is critical for membrane targeting and cell signaling. Because cancer cells often have increased N-myristoyltransferase (NMT) expression, NMTs were proposed as ant
Publikováno v:
Archives of oral biology. 121
Objective Clarifying the discrepancy between frequently high oxalate concentrations present in saliva, but negligible amounts of calcium oxalate deposits found on oral surfaces. Methods Studying the calcium oxalate concentration range that can lead t
Autor:
Erwan Beauchamp, Aishwarya Iyer, Naveen Pemmaraju, Joseph Brandwein, Krista Vincent, Luc G. Berthiaume, Gautam Borthakur, John R. Mackey, Jay M. Gamma, Megan Yap, Lynne M. Postovit, Zoulika Zak, Cassidy Ekstrom
Publikováno v:
Blood. 138:4344-4344
Background: N-terminal myristoylation is the transfer of the saturated fourteen carbon fatty acid myristate to an N-terminal glycine residue. This co- or post-translational protein modification promotes protein-protein and protein-lipid interactions
Autor:
Lynne-Marie Postovit, Krista Vincent
Publikováno v:
Anatomy and Cell Biology Publications
Tumours are complex entities, wherein cancer cells interact with myriad soluble, insoluble and cell associated factors. These microenvironmental mediators regulate tumour growth, progression and metastasis, and are produced by cancer cells and by str
Autor:
Desmond Pink, Nicole Favis, Krista Vincent, Mary M. Hitt, John D. Lewis, Chad R. Irwin, Kyle Potts, Ronald B. Moore, David H. Evans
Publikováno v:
EMBO Molecular Medicine
Bladder cancer has a recurrence rate of up to 80% and many patients require multiple treatments that often fail, eventually leading to disease progression. In particular, standard of care for high‐grade disease, Bacillus Calmette–Guerin (BCG), fa