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Temporal Impact of Substrate Anisotropy on Differentiating Cardiomyocyte Alignment and Functionality
Autor:
Nima Momtahan, Chengyi Tu, Cody O. Crosby, Krista Polansky, Alicia C.B. Allen, Janet Zoldan, Elissa Barone, Wei Deng
Publikováno v:
Tissue Eng Part A
Anisotropic biomaterials can affect cell function by driving cell alignment, which is critical for cardiac engineered tissues. Recent work, however, has shown that pluripotent stem cell-derived cardiomyocytes may self-align over long periods of time.